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Protein

50S ribosomal protein L2

Gene

rplB

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciHPY:HP1316-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L2UniRule annotation
Gene namesi
Name:rplBUniRule annotation
Ordered Locus Names:HP_1316
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001295691 – 27650S ribosomal protein L2Add BLAST276

Proteomic databases

PaxDbiP56030.

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

Protein-protein interaction databases

DIPiDIP-3298N.
IntActiP56030. 7 interactors.
MINTiMINT-162822.
STRINGi85962.HP1316.

Structurei

3D structure databases

ProteinModelPortaliP56030.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL2 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFD. Bacteria.
COG0090. LUCA.
KOiK02886.
OMAiHGYIKGV.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
4.10.950.10. 1 hit.
HAMAPiMF_01320_B. Ribosomal_L2_B. 1 hit.
InterProiView protein in InterPro
IPR012340. NA-bd_OB-fold.
IPR022666. Rbsml_prot_L2_RNA-bd_dom.
IPR014722. Rib_L2_dom2.
IPR002171. Ribosomal_L2.
IPR005880. Ribosomal_L2_bac/org-type.
IPR022669. Ribosomal_L2_C.
IPR022671. Ribosomal_L2_CS.
IPR014726. Ribosomal_L2_dom3.
IPR008991. Translation_prot_SH3-like_sf.
PANTHERiPTHR13691. PTHR13691. 1 hit.
PfamiView protein in Pfam
PF00181. Ribosomal_L2. 1 hit.
PF03947. Ribosomal_L2_C. 1 hit.
PIRSFiPIRSF002158. Ribosomal_L2. 1 hit.
SMARTiView protein in SMART
SM01383. Ribosomal_L2. 1 hit.
SM01382. Ribosomal_L2_C. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR01171. rplB_bact. 1 hit.
PROSITEiView protein in PROSITE
PS00467. RIBOSOMAL_L2. 1 hit.

Sequencei

Sequence statusi: Complete.

P56030-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIKTYKPYT PSRRFMSVLD SKDITAKSSV KGLLTKLKAT AGRNNNGRIT
60 70 80 90 100
SRHKERGAKK LYRIIDFKRN KYNIEGKVAA IEYDPYRNAR IALVVYPDGD
110 120 130 140 150
KRYILQPSGL KVGDSVIAAE GGLDIKVGFA MKLKNIPIGT VVHNIEMHPG
160 170 180 190 200
AGGQLARSAG MSAQIMGREN KYTIIRMPSS EMRYILSECM ASVGVVGNED
210 220 230 240 250
FINVSIGKAG RNRHRGIRPQ TRGSAMNPVD HPHGGGEGKT GTSGHPVSPW
260 270
GTPAKGYKTR KKKASDKLII SRKKHK
Length:276
Mass (Da):30,271
Last modified:November 1, 1997 - v1
Checksum:i5DCA6F36726C9A35
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08355.1.
PIRiD64684.
RefSeqiNP_208108.1. NC_000915.1.
WP_000985807.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08355; AAD08355; HP_1316.
GeneIDi900326.
KEGGiheo:C694_06795.
hpy:HP1316.
PATRICifig|85962.47.peg.1410.

Similar proteinsi

Entry informationi

Entry nameiRL2_HELPY
AccessioniPrimary (citable) accession number: P56030
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 22, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families