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Protein

Succinyl-CoA:3-ketoacid coenzyme A transferase subunit B

Gene

scoB

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei43PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

BioCyciHPY:HP0692-MONOMER.
MetaCyc:HP0692-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinyl-CoA:3-ketoacid coenzyme A transferase subunit B (EC:2.8.3.5)
Alternative name(s):
OXCT B
Succinyl-CoA:3-oxoacid CoA-transferase
Gene namesi
Name:scoB
Ordered Locus Names:HP_0692
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001579211 – 207Succinyl-CoA:3-ketoacid coenzyme A transferase subunit BAdd BLAST207

Proteomic databases

PaxDbiP56007.

Interactioni

Subunit structurei

Heterodimer of a subunit A and a subunit B.

Binary interactionsi

WithEntry#Exp.IntActNotes
scoAP560063EBI-7724043,EBI-7723842

Protein-protein interaction databases

DIPiDIP-3482N.
IntActiP56007. 4 interactors.
MINTiMINT-168328.
STRINGi85962.HP0692.

Structurei

Secondary structure

1207
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi2 – 10Combined sources9
Beta strandi18 – 21Combined sources4
Helixi25 – 33Combined sources9
Beta strandi34 – 36Combined sources3
Beta strandi39 – 42Combined sources4
Turni43 – 45Combined sources3
Beta strandi46 – 49Combined sources4
Beta strandi67 – 69Combined sources3
Beta strandi72 – 78Combined sources7
Helixi81 – 89Combined sources9
Beta strandi94 – 98Combined sources5
Beta strandi101 – 104Combined sources4
Beta strandi112 – 114Combined sources3
Turni115 – 117Combined sources3
Helixi125 – 131Combined sources7
Beta strandi132 – 138Combined sources7
Beta strandi148 – 153Combined sources6
Beta strandi159 – 162Combined sources4
Beta strandi165 – 168Combined sources4
Beta strandi170 – 177Combined sources8
Beta strandi180 – 186Combined sources7
Helixi192 – 198Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RRLX-ray2.29B/D1-207[»]
ProteinModelPortaliP56007.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4108IIH. Bacteria.
COG2057. LUCA.
KOiK01029.
OMAiTIDADMI.

Family and domain databases

InterProiIPR012791. 3-oxoacid_CoA-transf_B.
IPR004165. CoA_trans_fam_I.
IPR004164. CoA_transf_AS.
[Graphical view]
PANTHERiPTHR13707. PTHR13707. 1 hit.
PfamiPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTiSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02428. pcaJ_scoB_fam. 1 hit.
PROSITEiPS01274. COA_TRANSF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P56007-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREAIIKRAA KELKEGMYVN LGIGLPTLVA NEVSGMNIVF QSENGLLGIG
60 70 80 90 100
AYPLEGSVDA DLINAGKETI TVVPGASFFN SADSFAMIRG GHIDLAILGG
110 120 130 140 150
MEVSQNGDLA NWMIPKKLIK GMGGAMDLVH GAKKVIVIME HCNKYGESKV
160 170 180 190 200
KKECSLPLTG KGVVHQLITD LAVFEFSNNA MKLVELQEGV SLDQVKEKTE

AEFEVRL
Length:207
Mass (Da):22,263
Last modified:November 1, 1997 - v1
Checksum:i1A4AC53C70A90F81
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti70I → V in CAA03917 (PubMed:9325289).Curated1
Sequence conflicti196K → R in CAA03917 (PubMed:9325289).Curated1
Sequence conflicti206R → H in CAA03917 (PubMed:9325289).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07744.1.
AJ000086 Genomic DNA. Translation: CAA03917.1.
PIRiD64606.
RefSeqiNP_207486.1. NC_000915.1.
WP_001206261.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07744; AAD07744; HP_0692.
GeneIDi899313.
KEGGiheo:C694_03565.
hpy:HP0692.
PATRICi20592669. VBIHelPyl33062_0723.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07744.1.
AJ000086 Genomic DNA. Translation: CAA03917.1.
PIRiD64606.
RefSeqiNP_207486.1. NC_000915.1.
WP_001206261.1. NC_018939.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RRLX-ray2.29B/D1-207[»]
ProteinModelPortaliP56007.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-3482N.
IntActiP56007. 4 interactors.
MINTiMINT-168328.
STRINGi85962.HP0692.

Proteomic databases

PaxDbiP56007.

Protocols and materials databases

DNASUi899313.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD07744; AAD07744; HP_0692.
GeneIDi899313.
KEGGiheo:C694_03565.
hpy:HP0692.
PATRICi20592669. VBIHelPyl33062_0723.

Phylogenomic databases

eggNOGiENOG4108IIH. Bacteria.
COG2057. LUCA.
KOiK01029.
OMAiTIDADMI.

Enzyme and pathway databases

BioCyciHPY:HP0692-MONOMER.
MetaCyc:HP0692-MONOMER.

Family and domain databases

InterProiIPR012791. 3-oxoacid_CoA-transf_B.
IPR004165. CoA_trans_fam_I.
IPR004164. CoA_transf_AS.
[Graphical view]
PANTHERiPTHR13707. PTHR13707. 1 hit.
PfamiPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTiSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02428. pcaJ_scoB_fam. 1 hit.
PROSITEiPS01274. COA_TRANSF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSCOB_HELPY
AccessioniPrimary (citable) accession number: P56007
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 5, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.