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P56006 (SCOA_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A
EC=2.8.3.5
Alternative name(s):
Succinyl CoA:3-oxoacid CoA-transferase
Short name=OXCT A
Gene names
Name:scoA
Ordered Locus Names:HP_0691
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA. Ref.2

Subunit structure

Heterodimer of a subunit A and a subunit B.

Sequence similarities

Belongs to the 3-oxoacid CoA-transferase subunit A family.

Ontologies

Keywords
   Molecular functionTransferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Molecular function3-oxoacid CoA-transferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 232232Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A
PRO_0000157909

Regions

Region24 – 307CoA-binding Potential

Experimental info

Sequence conflict141A → T no nucleotide entry Ref.2
Sequence conflict108 – 1092HA → RP no nucleotide entry Ref.2
Sequence conflict116 – 1216AYYTPT → LTTPQP no nucleotide entry Ref.2
Sequence conflict129 – 13911QGKESREFNGK → PRQGIQGSLTAR no nucleotide entry Ref.2
Sequence conflict2311T → A no nucleotide entry Ref.2

Secondary structure

1 ........................................... 232
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P56006 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 83CFEE57C0192F3D

FASTA23225,362
        10         20         30         40         50         60 
MNKVITDLDK ALSALKDGDT ILVGGFGLCG IPEYAIDYIY KKGIKDLIVV SNNCGVDDFG 

        70         80         90        100        110        120 
LGILLEKKQI KKIIASYVGE NKIFESQMLN GEIEVVLTPQ GTLAENLHAG GAGIPAYYTP 

       130        140        150        160        170        180 
TGVGTLIAQG KESREFNGKE YILERAITGD YGLIKAYKSD TLGNLVFRKT ARNFNPLCAM 

       190        200        210        220        230 
AAKICVAEVE EIVPAGELDP DEIHLPGIYV QHIYKGEKFE KRIEKITTRS TK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000511 Genomic DNA. Translation: AAD07743.1.
PIRC64606.
RefSeqNP_207485.1. NC_000915.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3RRLX-ray2.29A/C1-232[»]
ProteinModelPortalP56006.
SMRP56006. Positions 1-229.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-3481N.
MINTMINT-176385.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID899012.
GenomeReviewsGene locus HP_0691 in contig AE000511_GR.
KEGGhpy:HP0691.
NMPDRfig|85962.1.peg.683.
PATRIC20592667. VBIHelPyl33062_0722.
TIGRHP_0691.

Phylogenomic databases

HOGENOMHBG288750.
OMAGEHEKRI.
ProtClustDBCLSK496160.

Enzyme and pathway databases

BioCycMetaCyc:HP0691-MONOMER.

Family and domain databases

InterProIPR012792. 3-oxoacid_CoA-transf_A.
IPR004165. CoA_trans.
IPR004163. CoA_transf_BS.
[Graphical view]
KOK01028.
PANTHERPTHR13707. CoA_trans. 1 hit.
PfamPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsTIGR02429. PcaI_scoA_fam. 1 hit.
PROSITEPS01273. COA_TRANSF_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSCOA_HELPY
AccessionPrimary (citable) accession number: P56006
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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