P55975 (EFTS_HELPY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor Ts
Short name=EF-Ts

Gene names

Name:	tsf
Ordered Locus Names:	HP_1555

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	355 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome By similarity. HAMAP-Rule MF_00050
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the EF-Ts family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 355	355	Elongation factor Ts HAMAP-Rule MF_00050		PRO_0000161131
Regions
	Region	82 – 85	4	Involved in Mg(2+) ion dislocation from EF-Tu By similarity

Sequences

	Sequence		Length	Mass (Da)
	P55975 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: A029F9BC57C7F101	FASTA	355	39,695
	10 20 30 40 50 60 MSGISAQLVK KLRDLTDAGM MDCKKALVEV AGDLQKAIDF LREKGLSKAA KKADRIAAEG 70 80 90 100 110 120 VVALEVAPDF KSAMIVEINS ETDFVAKNEG FKELVKKTLE TIKAHNIHTT EELLKSPLDN 130 140 150 160 170 180 KPFEEYLHSQ IAVIGENILV RKIAHLKAPS SHIINGYAHS NARVGVLIGI KYDNEKNAPK 190 200 210 220 230 240 VVELARNIAM HAAAMKPQVL DCKDFSLDFV KKETLALIAE IEKDNEEAKR LGKPLKNIPT 250 260 270 280 290 300 FGSRIELSDE VLAHQKKAFE DELKAQGKPE KIWDKIVPGK MERFIADNTL IDQRLTLLGQ 310 320 330 340 350 FYVMDDKKTI AQVVADCSKE WNDDLKITEY VRFELGEGIE KKAENFAEEV ALQMK

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD08595.1.
PIR	C64714.
RefSeq	NP_208346.1. NC_000915.1. YP_006935481.1. NC_018939.1.
3D structure databases
ProteinModelPortal	P55975.
ModBase	Search...
Protein-protein interaction databases
STRING	85962.HP1555.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAD08595; AAD08595; HP_1555.
GeneID	13870774. 899736.
KEGG	heo:C694_08055. hpy:HP1555.
PATRIC	20594533. VBIHelPyl33062_1634.
Phylogenomic databases
eggNOG	COG0264.
KO	K02357.
OMA	YLHGTRI.
ProtClustDB	PRK09377.
Family and domain databases
Gene3D	3.30.479.20. 3 hits.
HAMAP	MF_00050. EF_Ts.
InterPro	IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR018101. Transl_elong_Ts_CS. IPR009060. UBA-like. IPR000449. UBA/transl_elong_EF1B_N. [Graphical view]
PANTHER	PTHR11741. PTHR11741. 1 hit.
Pfam	PF00889. EF_TS. 1 hit. PF00627. UBA. 1 hit. [Graphical view]
SUPFAM	SSF54713. EF_TS. 1 hit. SSF46934. UBA_like. 1 hit.
TIGRFAMs	TIGR00116. tsf. 1 hit.
PROSITE	PS01126. EF_TS_1. 1 hit. PS01127. EF_TS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTS_HELPY

Accession

Primary (citable) accession number: P55975

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program