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Protein

Elongation factor Ts

Gene

tsf

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciHPY:HP1555-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor Ts
Short name:
EF-Ts
Gene namesi
Name:tsf
Ordered Locus Names:HP_1555
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 355355Elongation factor TsPRO_0000161131Add
BLAST

Proteomic databases

PRIDEiP55975.

Interactioni

Protein-protein interaction databases

STRINGi85962.HP1555.

Structurei

3D structure databases

ProteinModelPortaliP55975.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni82 – 854Involved in Mg(2+) ion dislocation from EF-TuBy similarity

Sequence similaritiesi

Belongs to the EF-Ts family.Curated

Phylogenomic databases

eggNOGiCOG0264.
KOiK02357.
OMAiHSQIAVI.
OrthoDBiEOG66B42N.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
IPR000449. UBA/Ts_N.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
PF00627. UBA. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 3 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P55975-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGISAQLVK KLRDLTDAGM MDCKKALVEV AGDLQKAIDF LREKGLSKAA
60 70 80 90 100
KKADRIAAEG VVALEVAPDF KSAMIVEINS ETDFVAKNEG FKELVKKTLE
110 120 130 140 150
TIKAHNIHTT EELLKSPLDN KPFEEYLHSQ IAVIGENILV RKIAHLKAPS
160 170 180 190 200
SHIINGYAHS NARVGVLIGI KYDNEKNAPK VVELARNIAM HAAAMKPQVL
210 220 230 240 250
DCKDFSLDFV KKETLALIAE IEKDNEEAKR LGKPLKNIPT FGSRIELSDE
260 270 280 290 300
VLAHQKKAFE DELKAQGKPE KIWDKIVPGK MERFIADNTL IDQRLTLLGQ
310 320 330 340 350
FYVMDDKKTI AQVVADCSKE WNDDLKITEY VRFELGEGIE KKAENFAEEV

ALQMK
Length:355
Mass (Da):39,695
Last modified:November 1, 1997 - v1
Checksum:iA029F9BC57C7F101
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08595.1.
PIRiC64714.
RefSeqiNP_208346.1. NC_000915.1.
WP_000014397.1. NC_018939.1.
YP_006935481.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08595; AAD08595; HP_1555.
GeneIDi899736.
KEGGiheo:C694_08055.
hpy:HP1555.
PATRICi20594533. VBIHelPyl33062_1634.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08595.1.
PIRiC64714.
RefSeqiNP_208346.1. NC_000915.1.
WP_000014397.1. NC_018939.1.
YP_006935481.1. NC_018939.1.

3D structure databases

ProteinModelPortaliP55975.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi85962.HP1555.

Proteomic databases

PRIDEiP55975.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD08595; AAD08595; HP_1555.
GeneIDi899736.
KEGGiheo:C694_08055.
hpy:HP1555.
PATRICi20594533. VBIHelPyl33062_1634.

Phylogenomic databases

eggNOGiCOG0264.
KOiK02357.
OMAiHSQIAVI.
OrthoDBiEOG66B42N.

Enzyme and pathway databases

BioCyciHPY:HP1555-MONOMER.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
IPR000449. UBA/Ts_N.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
PF00627. UBA. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 3 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiEFTS_HELPY
AccessioniPrimary (citable) accession number: P55975
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 27, 2015
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.