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P55973 (IF3_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Translation initiation factor IF-3
Gene names
Name:infC
Ordered Locus Names:HP_0124
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. HAMAP MF_00080

Subunit structure

Monomer By similarity. HAMAP MF_00080

Subcellular location

Cytoplasm HAMAP MF_00080.

Sequence similarities

Belongs to the IF-3 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionInitiation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 203203Translation initiation factor IF-3 HAMAP MF_00080
PRO_0000177525

Sequences

Sequence LengthMass (Da)Tools
P55973 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 65B38BFD36CD8003

FASTA20323,342
        10         20         30         40         50         60 
MSRNEVLLNG DINFKEVRCV GDNGEVYGII SSKEALHIAQ NLGLDLVLIS ASAKPPVCKV 

        70         80         90        100        110        120 
MDYNKFRYQN EKKIKEAKKK QKQIEIKEIK LSTQIAQNDI NYKVKHAREF IESNKHVKFK 

       130        140        150        160        170        180 
VVLKGRESQN SKAGLDVLFR VQTMMQDLAN PEKEPKTEGR FVSWMFVPKA KEAPKNEKKT 

       190        200 
KENNPPFNRI NLMKGENHAK NED 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD07193.1.
PIRD64535.
RefSeqNP_206924.1. NC_000915.1.

3D structure databases

ProteinModelPortalP55973.
SMRP55973. Positions 5-79.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-3195N.
MINTMINT-171266.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID899823.
GenomeReviewsGene locus HP_0124 in contig AE000511_GR.
KEGGhpy:HP0124.
NMPDRfig|85962.1.peg.122.
PATRIC20591465. VBIHelPyl33062_0132.
TIGRHP_0124.

Phylogenomic databases

HOGENOMHBG744268.
OMAFDRRAPV.
ProtClustDBPRK00028.

Family and domain databases

HAMAPMF_00080. IF-3.
[Tree]
InterProIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
Gene3DG3DSA:3.10.20.80. IF3. 1 hit.
G3DSA:3.30.110.10. IF3. 1 hit.
KOK02520.
PANTHERPTHR10938. IF3. 1 hit.
PfamPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMSSF54364. IF3. 1 hit.
SSF55200. IF3. 1 hit.
TIGRFAMsTIGR00168. InfC. 1 hit.
PROSITEPS00938. IF3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF3_HELPY
AccessionPrimary (citable) accession number: P55973
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Translation initiation factors

List of translation initiation factor entries

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names

SIMILARITY comments

Index of protein domains and families