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Protein

Metallothionein-1B

Gene
N/A
Organism
Callinectes sapidus (Blue crab)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Binds six divalent metal ions. Known to bind copper and cadmium.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi5Divalent metal cation; cluster B1
Metal bindingi6Divalent metal cation; cluster B1
Metal bindingi10Divalent metal cation; cluster B1
Metal bindingi12Divalent metal cation; cluster B1
Metal bindingi17Divalent metal cation; cluster B1
Metal bindingi21Divalent metal cation; cluster B1
Metal bindingi23Divalent metal cation; cluster B1
Metal bindingi26Divalent metal cation; cluster B1
Metal bindingi28Divalent metal cation; cluster B1
Metal bindingi31Divalent metal cation; cluster A1
Metal bindingi34Divalent metal cation; cluster A1
Metal bindingi38Divalent metal cation; cluster A1
Metal bindingi40Divalent metal cation; cluster A1
Metal bindingi46Divalent metal cation; cluster A1
Metal bindingi50Divalent metal cation; cluster A1
Metal bindingi54Divalent metal cation; cluster A1
Metal bindingi56Divalent metal cation; cluster A1
Metal bindingi57Divalent metal cation; cluster A1

GO - Molecular functioni

Keywordsi

LigandCadmium, Copper, Metal-binding, Metal-thiolate cluster

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein-1B
Short name:
MT-1B
Alternative name(s):
Metallothionein-IB
Short name:
MT-IB
Cleaved into the following chain:
Metallothionein-1A
Short name:
MT-1A
Alternative name(s):
Metallothionein-IA
Short name:
MT-IA
OrganismiCallinectes sapidus (Blue crab)
Taxonomic identifieri6763 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataBrachyuraEubrachyuraPortunoideaPortunidaeCallinectes

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000417541 – 59Metallothionein-1BAdd BLAST59
ChainiPRO_00000417552 – 59Metallothionein-1AAdd BLAST58

Structurei

Secondary structure

159
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni12 – 15Combined sources4
Beta strandi24 – 26Combined sources3
Turni32 – 37Combined sources6
Helixi43 – 49Combined sources7
Beta strandi55 – 57Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1DMCNMR-A29-59[»]
1DMDNMR-A29-59[»]
1DMENMR-A2-29[»]
1DMFNMR-A2-29[»]
ProteinModelPortaliP55949.
SMRiP55949.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP55949.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 29BetaAdd BLAST29
Regioni30 – 59AlphaAdd BLAST30

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR002045. Metalthion_crustacean.
IPR017854. Metalthion_dom.
PRINTSiPR00858. MTCRUSTACEAN.
SUPFAMiSSF57868. SSF57868. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P55949-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGPCCNDKC VCQEGGCKAG CQCTSCRCSP CQKCTSGCKC ATKEECSKTC

TKPCSCCPK
Length:59
Mass (Da):6,141
Last modified:November 1, 1997 - v1
Checksum:i4398B0A9D1A96D34
GO

Sequence databases

PIRiS59072.

Similar proteinsi

Entry informationi

Entry nameiMT1_CALSI
AccessioniPrimary (citable) accession number: P55949
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. Metallothioneins
    Classification of metallothioneins and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families