Reviewed, UniProtKB/Swiss-Prot P55906 (BGH3_BOVIN)

Names and origin

Protein names

Recommended name:
    Transforming growth factor-beta-induced protein ig-h3
      Short name=Beta ig-h3
Alternative name(s):
    MP78
    MP70

Gene names

Name:	TGFBI
Synonyms:	BIGH3

Organism

Bos taurus (Bovine)

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	87 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation By similarity.
Subcellular location	Secreted › extracellular space › extracellular matrix. Note= May be associated both with microfibrils and with the cell surface.
Induction	By TGF-beta.

Ontologies

Keywords
Biological process	Cell adhesion
Cellular component	Extracellular matrix Secreted
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	cell adhesion Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	proteinaceous extracellular matrix Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	protein binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 87	87	Transforming growth factor-beta-induced protein ig-h3		PRO_0000203524
Experimental info
	Non-adjacent residues	13 – 14	2
	Non-adjacent residues	36 – 37	2
	Non-adjacent residues	59 – 60	2

Sequences

	Sequence		Length	Mass (Da)
	P55906-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: B216AE63E4A7D9B1	FASTA	87	9,455
	10 20 30 40 50 60 GRARSPYQLV LQHMNSVFKD GRPPINARXK NLLLNHMDVL KGDNRFSMLV AAIQSAGLTM 70 80 ADNGVDHAIS XVLQPPANAP QENGDDL

References

[1]

"Further characterization of proteins associated with elastic fiber microfibrils including the molecular cloning of MAGP-2 (MP25)." Gibson M.A., Hatzinikolas G., Kumaratilake J.S., Sandberg L.B., Nicholl J.K., Sutherland G.R., Cleary E.G. J. Biol. Chem. 271:1096-1103(1996) [PubMed: 8557636] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

Sequence databases
UniGene	Bt.46833
3D structure databases
ModBase	Search...
Phylogenomic databases
HOVERGEN	P55906.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

BGH3_BOVIN

Accession

Primary (citable) accession number: P55906

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	November 4, 2008
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)