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Reviewed, UniProtKB/Swiss-Prot P55879 (GLI3_CHICK)

Last modified November 25, 2008. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Zinc finger protein GLI3
Gene names
Name: GLI3
OrganismGallus gallus (Chicken)
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length663 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Function

Implicated in the transduction of Shh signal By similarity.

Subcellular location

Nucleus.

Sequence similarities

Belongs to the GLI C2H2-type zinc-finger protein family.

Contains at least 5 C2H2-type zinc fingers.

Ontologies

Keywords

   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainRepeat
Zinc-finger
   LigandDNA-binding
Metal-binding
Zinc

Gene Ontology (GO)

   Cellular componentnucleus

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionzinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›663›663Zinc finger protein GLI3
PRO_0000047205

Regions

Zinc finger234 – 25926C2H2-type
Zinc finger267 – 29428C2H2-type
Zinc finger300 – 32425C2H2-type
Zinc finger330 – 35526C2H2-type
Zinc finger361 – 38626C2H2-type

Experimental info

Non-terminal residue11
Non-terminal residue6631

Sequences

Sequence LengthMass (Da)Tools
P55879-1 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 46E32C33FF6BD4FF

FASTA66373,107
        10         20         30         40         50         60 
LMAGHPNYGD ILMQSGGAAG TAHLHEYLSP VDVSRFSSPR VTPRLSRKRA LSISPLSDAS 

        70         80         90        100        110        120 
IDLQTMIRTS PNSLVAYINN SRSSSAASGS YGHLSAGTIS PAFSFPHPIN PVTYQQILTQ 

       130        140        150        160        170        180 
QRGLSSAFGH TPPLIQPSPT FPPRQHMAVI SVNPPPAQIS SNSNCISDSS QSKQSSESAV 

       190        200        210        220        230        240 
SSTVNPVINK RTKVKTEVEG LPQYPQPRQE HLTDLKEDLD KDECKQEPEV IYETNCHWEG 

       250        260        270        280        290        300 
CTKEYDTQEQ LVHHINNDHI HGEKKEFVCR WQDCTREQKP FKAQYMLVVH MRRHTGEKPH 

       310        320        330        340        350        360 
KCTFEGCSKA YSRLENLKTH LRSHTGEKPY VCEHEGCNKA FSNASDRAKH QNRTHSNEKP 

       370        380        390        400        410        420 
YVCKIPGCTK RYTDPSSLRK HVKTVHGPDA HVTKKQRNDV HPRPPPLKEN GDNEASAKQS 

       430        440        450        460        470        480 
SKVSEESPEA NSTTRSMEDC LQVKTIKTEN SVMCQSSPGG QSSCSSEPSP LGSTNNNDSG 

       490        500        510        520        530        540 
VEMNMHGGGS LGDLTGWMTR LPVVDSTVSS GNLTVSLQLR KHMTTMQRLE QLKKEKLKTV 

       550        560        570        580        590        600 
KDSCSWVNPA PQGRNTKLPP ISGNGSILEN SGGSSRTLPN PRIMELSVNE VTMLNQINER 

       610        620        630        640        650        660 
RDSTTSTISS AYTVSRRSSG ISPYFSSRRS SEASQLGHRP NNTSSADSYD PISTGGREFD 


IKL 

« Hide

References

[1]"Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development."
Marigo V., Johnson R.L., Vortkamp A., Tabin C.J.
Dev. Biol. 180:273-283(1996) [PubMed: 8948590] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

U60763 mRNA. Translation: AAB51660.1.
UniGeneGga.4969

3D structure databases

HSSPHSSP built from PDB template 2GLI based on UniProtKB P08151.
ModBaseSearch...

Genome annotation databases

EnsemblENSGALG00000011630. Gallus gallus. [Contig view]

Phylogenomic databases

HOVERGENP55879.

Family and domain databases

InterProIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
Gene3DG3DSA:3.30.160.60. Znf_C2H2/integrase_DNA-bd. 4 hits.
PfamPF00096. zf-C2H2. 5 hits.
[Graphical view]
ProDomPD000003. Znf_C2H2. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLI3_CHICK
AccessionPrimary (citable) accession number: P55879
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 25, 2008
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents