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Protein

Translation initiation factor IF-3

Gene

infC

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciBSUB:BSU28870-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-3UniRule annotation
Gene namesi
Name:infCUniRule annotation
Ordered Locus Names:BSU28870
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570 Componenti: Chromosome

Organism-specific databases

GenoListiBSU28870. [Micado]

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 173172Translation initiation factor IF-3PRO_0000177482Add
BLAST

Proteomic databases

PaxDbiP55872.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

IntActiP55872. 1 interaction.
MINTiMINT-8366385.
STRINGi224308.Bsubs1_010100015761.

Structurei

3D structure databases

ProteinModelPortaliP55872.
SMRiP55872. Positions 4-79, 84-171.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the IF-3 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0290.
HOGENOMiHOG000035157.
InParanoidiP55872.
KOiK02520.
OMAiHDFNVKV.
OrthoDBiEOG63JRGJ.
PhylomeDBiP55872.

Family and domain databases

Gene3Di3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPiMF_00080. IF_3.
InterProiIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERiPTHR10938. PTHR10938. 1 hit.
PfamiPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMiSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsiTIGR00168. infC. 1 hit.
PROSITEiPS00938. IF3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P55872-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISKDQLVNE GIRAREVRLI GQNGDQLGIK SRQEALEIAG RANLDLVLVA
60 70 80 90 100
ANAKPPVCRI MDYGKFRFEQ QKKEKEARKN QKIINLKEVR LSPTIDEHDF
110 120 130 140 150
NTKLRNAIKF LEKGDKVKAS IRFKGRAITH KEIGQRVLDR FSEACAEVAT
160 170
VETKPKMDGR SMFLMLAPKN EKQ
Length:173
Mass (Da):19,732
Last modified:May 26, 2009 - v3
Checksum:i9090760908AB0751
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75208 Genomic DNA. Translation: CAA99616.1.
AL009126 Genomic DNA. Translation: CAB14847.1.
PIRiH69644.
RefSeqiNP_390765.1. NC_000964.3.
WP_010886591.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB14847; CAB14847; BSU28870.
GeneIDi937835.
KEGGibsu:BSU28870.
PATRICi18977666. VBIBacSub10457_3021.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75208 Genomic DNA. Translation: CAA99616.1.
AL009126 Genomic DNA. Translation: CAB14847.1.
PIRiH69644.
RefSeqiNP_390765.1. NC_000964.3.
WP_010886591.1. NC_000964.3.

3D structure databases

ProteinModelPortaliP55872.
SMRiP55872. Positions 4-79, 84-171.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP55872. 1 interaction.
MINTiMINT-8366385.
STRINGi224308.Bsubs1_010100015761.

Proteomic databases

PaxDbiP55872.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14847; CAB14847; BSU28870.
GeneIDi937835.
KEGGibsu:BSU28870.
PATRICi18977666. VBIBacSub10457_3021.

Organism-specific databases

GenoListiBSU28870. [Micado]

Phylogenomic databases

eggNOGiCOG0290.
HOGENOMiHOG000035157.
InParanoidiP55872.
KOiK02520.
OMAiHDFNVKV.
OrthoDBiEOG63JRGJ.
PhylomeDBiP55872.

Enzyme and pathway databases

BioCyciBSUB:BSU28870-MONOMER.

Family and domain databases

Gene3Di3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPiMF_00080. IF_3.
InterProiIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERiPTHR10938. PTHR10938. 1 hit.
PfamiPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMiSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsiTIGR00168. infC. 1 hit.
PROSITEiPS00938. IF3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The dnaB-pheA (256 degrees-240 degrees) region of the Bacillus subtilis chromosome containing genes responsible for stress responses, the utilization of plant cell walls and primary metabolism."
    Wipat A., Carter N., Brignell C.S., Guy J.B., Piper K., Sanders J., Emmerson P.T., Harwood C.R.
    Microbiology 142:3067-3078(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.

Entry informationi

Entry nameiIF3_BACSU
AccessioniPrimary (citable) accession number: P55872
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 26, 2009
Last modified: July 22, 2015
This is version 103 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. Translation initiation factors
    List of translation initiation factor entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.