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P55858

- RL7A_SULSO

UniProt

P55858 - RL7A_SULSO

Protein

50S ribosomal protein L7Ae

Gene

rpl7ae

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 2 (27 Apr 2001)
      Previous versions | rss
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    Functioni

    Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-HAMAP
    2. rRNA binding Source: UniProtKB-KW
    3. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. ribosome biogenesis Source: InterPro
    2. translation Source: UniProtKB-HAMAP
    3. tRNA 5'-leader removal Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciSSOL273057:GCH2-87-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L7AeUniRule annotation
    Alternative name(s):
    Ribosomal protein L8eUniRule annotation
    Gene namesi
    Name:rpl7aeUniRule annotation
    Ordered Locus Names:SSO0091
    ORF Names:C04_031
    OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
    Taxonomic identifieri273057 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
    ProteomesiUP000001974: Chromosome

    Subcellular locationi

    Cytoplasm 1 PublicationUniRule annotation
    Note: Found free in the cytoplasm and associated with the 50S ribosomal subunit.

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 12712750S ribosomal protein L7AePRO_0000136806Add
    BLAST

    Expressioni

    Inductioni

    Constitutuively expressed (at protein level).1 Publication

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA. These sRNP particles form homodimers, giving rise to an asymmetric holoenzyme. Probably part of the RNase P complex.2 Publications

    Protein-protein interaction databases

    DIPiDIP-48940N.
    IntActiP55858. 1 interaction.
    STRINGi273057.SSO0091.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3ID5X-ray4.01C/G1-127[»]
    ProteinModelPortaliP55858.
    SMRiP55858. Positions 6-124.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP55858.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L7Ae family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1358.
    HOGENOMiHOG000055225.
    KOiK02936.
    OMAiRKGTNEV.

    Family and domain databases

    Gene3Di3.30.1330.30. 1 hit.
    HAMAPiMF_00326. Ribosomal_L7Ae_Arch.
    InterProiIPR029064. L30e-like.
    IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
    IPR018492. Ribosomal_L7Ae/L8/Nhp2.
    IPR022481. Ribosomal_L7Ae_arc.
    IPR004037. Ribosomal_L7Ae_CS.
    IPR000948. Ribosomal_L7Ae_prok.
    [Graphical view]
    PfamiPF01248. Ribosomal_L7Ae. 1 hit.
    [Graphical view]
    PRINTSiPR00881. L7ARS6FAMILY.
    PR00884. RIBOSOMALHS6.
    SUPFAMiSSF55315. SSF55315. 1 hit.
    TIGRFAMsiTIGR03677. rpl7ae. 1 hit.
    PROSITEiPS01082. RIBOSOMAL_L7AE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P55858-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKASYVKFE VPQDLADKVL EAVRKAKESG KIKKGTNETT KAVERGQAKL    50
    VIIAEDVQPE EIVAHLPLLC DEKKIPYVYV SSKKALGEAC GLQVATASAA 100
    ILEPGEAKDL VDEIIKRVNE IKGKTSS 127
    Length:127
    Mass (Da):13,736
    Last modified:April 27, 2001 - v2
    Checksum:i3EE30FC81C1A003D
    GO

    Sequence cautioni

    The sequence AAK40449.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence CAA69560.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y08257 Genomic DNA. Translation: CAA69560.1. Different initiation.
    AE006641 Genomic DNA. Translation: AAK40449.1. Different initiation.
    PIRiS75397.
    RefSeqiNP_341659.1. NC_002754.1.

    Genome annotation databases

    EnsemblBacteriaiAAK40449; AAK40449; SSO0091.
    GeneIDi1453277.
    KEGGisso:SSO0091.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y08257 Genomic DNA. Translation: CAA69560.1 . Different initiation.
    AE006641 Genomic DNA. Translation: AAK40449.1 . Different initiation.
    PIRi S75397.
    RefSeqi NP_341659.1. NC_002754.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3ID5 X-ray 4.01 C/G 1-127 [» ]
    ProteinModelPortali P55858.
    SMRi P55858. Positions 6-124.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-48940N.
    IntActi P55858. 1 interaction.
    STRINGi 273057.SSO0091.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK40449 ; AAK40449 ; SSO0091 .
    GeneIDi 1453277.
    KEGGi sso:SSO0091.

    Phylogenomic databases

    eggNOGi COG1358.
    HOGENOMi HOG000055225.
    KOi K02936.
    OMAi RKGTNEV.

    Enzyme and pathway databases

    BioCyci SSOL273057:GCH2-87-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P55858.

    Family and domain databases

    Gene3Di 3.30.1330.30. 1 hit.
    HAMAPi MF_00326. Ribosomal_L7Ae_Arch.
    InterProi IPR029064. L30e-like.
    IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
    IPR018492. Ribosomal_L7Ae/L8/Nhp2.
    IPR022481. Ribosomal_L7Ae_arc.
    IPR004037. Ribosomal_L7Ae_CS.
    IPR000948. Ribosomal_L7Ae_prok.
    [Graphical view ]
    Pfami PF01248. Ribosomal_L7Ae. 1 hit.
    [Graphical view ]
    PRINTSi PR00881. L7ARS6FAMILY.
    PR00884. RIBOSOMALHS6.
    SUPFAMi SSF55315. SSF55315. 1 hit.
    TIGRFAMsi TIGR03677. rpl7ae. 1 hit.
    PROSITEi PS01082. RIBOSOMAL_L7AE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Organizational characteristics and information content of an archaeal genome: 156 kb of sequence from Sulfolobus solfataricus P2."
      Sensen C.W., Klenk H.-P., Singh R.K., Allard G., Chan C.C.-Y., Liu Q.Y., Penny S.L., Young F., Schenk M.E., Gaasterland T., Doolittle W.F., Ragan M.A., Charlebois R.L.
      Mol. Microbiol. 22:175-191(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.
    3. "Function and ribosomal localization of aIF6, a translational regulator shared by archaea and eukarya."
      Benelli D., Marzi S., Mancone C., Alonzi T., la Teana A., Londei P.
      Nucleic Acids Res. 37:256-267(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBUNIT, SUBCELLULAR LOCATION, INDUCTION.
    4. "Structural organization of box C/D RNA-guided RNA methyltransferase."
      Ye K., Jia R., Lin J., Ju M., Peng J., Xu A., Zhang L.
      Proc. Natl. Acad. Sci. U.S.A. 106:13808-13813(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (4.01 ANGSTROMS) IN COMPLEX WITH RNA; S-NOP5 AND FLPA, SUBUNIT.

    Entry informationi

    Entry nameiRL7A_SULSO
    AccessioniPrimary (citable) accession number: P55858
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: April 27, 2001
    Last modified: October 1, 2014
    This is version 93 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3