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Reviewed, UniProtKB/Swiss-Prot P55808 (XG_HUMAN)

Last modified November 25, 2008. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Glycoprotein Xg
Alternative name(s):
    Protein PBDX
Gene names
Name: XG
Synonyms: PBDX
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length180 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Subcellular location

Membrane; Single-pass type I membrane proteinPotential.

Post-translational modification

O-glycosylated Probable.

Polymorphism

XG is responsible for the Xg blood group system.

Miscellaneous

The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.

Sequence similarities

Belongs to the CD99 family.

Caution

Ref.3 sequence incorrectly indicated as originating from mouse.

Ontologies

Keywords

   Cellular componentMembrane
   DomainSignal
Transmembrane
   Molecular functionBlood group antigen
   PTMGlycoprotein

Gene Ontology (GO)

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 180159Glycoprotein Xg
PRO_0000022693

Regions

Topological domain22 – 142121Extracellular Potential
Transmembrane143 – 16321 Potential
Topological domain164 – 18017Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P55808-1 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: DADAA9E6859C4530

FASTA18019,723
        10         20         30         40         50         60 
MESWWGLPCL AFLCFLMHAR GQRDFDLADA LDDPEPTKKP NSDIYPKPKP PYYPQPENPD 

        70         80         90        100        110        120 
SGGNIYPRPK PRPQPQPGNS GNSGGYFNDV DRDDGRYPPR PRPRPPAGGG GGGYSSYGNS 

       130        140        150        160        170        180 
DNTHGGDHHS TYGNPEGNMV AKIVSPIVSV VVVTLLGAAA SYFKLNNRRN CFRTHEPENV 

« Hide

References

[1]"Cloning of PBDX, an MIC2-related gene that spans the pseudoautosomal boundary on chromosome Xp."
Ellis N.A., Ye T.Z., Patton S., German J., Goodfellow P.N., Weller P.
Nat. Genet. 6:394-400(1994) [PubMed: 8054981] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Bone marrow.
[2]"Identification of PBDX gene highly expressed in human cornea."
Naoko S., Fujiki K., Kanai A., Tanaka Y., Iwata T.
Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]"Molecular cloning and characterization of mouse PBDX."
Naoko S., Tanaka Y., Iwata T.
Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Web resources

BGMUT

Blood group antigen gene mutation database"

Cross-references

Sequence databases

X96421 Genomic DNA. No translation available.
AF380356 mRNA. Translation: AAL04055.1.
AF534880 mRNA. Translation: AAN03481.1.
PIRS43791.
RefSeqNP_780778.1.
UniGeneHs.179675

3D structure databases

ModBaseSearch...

PTM databases

PhosphoSiteP55808.

Genome annotation databases

EnsemblENSG00000124343. Homo sapiens. [Contig view]
GeneID7499.
KEGGhsa:7499.
NMPDRfig|9606.3.peg.32391.

Organism-specific databases

H-InvDBHIX0056172.
HGNCHGNC:12806. XG.
MIM314700. gene+phenotype.
PharmGKBPA37405.
GenAtlasSearch...
GeneCardsSearch...

Phylogenomic databases

HOVERGENP55808.

Gene expression databases

ArrayExpressP55808.
CleanExHS_XG.
GermOnlineENSG00000124343. Homo sapiens.

Family and domain databases

ProtoNetSearch...

Other Resources

LinkHubP55808.
NextBio29368.
SOURCESearch...

Entry information

Entry nameXG_HUMAN
AccessionPrimary (citable) accession number: P55808
Secondary accession number(s): Q71BZ5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 25, 2008
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

Relevant documents

Blood group antigen proteins

Nomenclature of blood group antigens and list of entries

Human chromosome X

Human chromosome X: entries, gene names and cross-references to MIM

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents