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P55747

- CBP21_HORVU

UniProt

P55747 - CBP21_HORVU

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Protein

Serine carboxypeptidase II-1

Gene

CXP;2-1

Organism
Hordeum vulgare (Barley)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

Preferential release of a C-terminal arginine or lysine residue.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei41 – 411By similarity
Active sitei239 – 2391By similarity
Active sitei291 – 2911By similarity

GO - Molecular functioni

  1. serine-type carboxypeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Carboxypeptidase, Hydrolase, Protease

Names & Taxonomyi

Protein namesi
Recommended name:
Serine carboxypeptidase II-1 (EC:3.4.16.6)
Alternative name(s):
CP-MII.1
Cleaved into the following 2 chains:
Gene namesi
Name:CXP;2-1
OrganismiHordeum vulgare (Barley)
Taxonomic identifieri4513 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeHordeum

Organism-specific databases

GrameneiP55747.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 149›149Serine carboxypeptidase II-1 chain APRO_0000004314Add
BLAST
Propeptidei150 – 16213Linker peptideBy similarityPRO_0000004315Add
BLAST
Chaini163 – 324162Serine carboxypeptidase II-1 chain BPRO_0000004316Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi10 – 101N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi109 ↔ 121By similarity
Disulfide bondi145 ↔ 170Interchain (between A and B chains)By similarity
Glycosylationi191 – 1911N-linked (GlcNAc...)Sequence Analysis

Post-translational modificationi

The linker peptide is endoproteolytically excised during enzyme maturation.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Zymogen

Expressioni

Developmental stagei

Expressed in the germinating embryo. Low levels in the developing aleurone and embryo. Also found in the roots and shoots of the growing seedling.

Gene expression databases

GenevestigatoriP55747.

Interactioni

Subunit structurei

Carboxypeptidase II is a dimer, where each monomer is composed of two chains linked by a disulfide bond.By similarity

Structurei

3D structure databases

ProteinModelPortaliP55747.
SMRiP55747. Positions 2-145, 167-315.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S10 family.Curated

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00560. CARBOXYPEPT_SER_HIS. 1 hit.
PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P55747-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
GSDLLTPGDN KTAHDSYAFL VNWLERFPQY KYRDFYIAGE SYAGHYVPQL
60 70 80 90 100
SQLVHRNNKG VRKPILNFKG FMVGNAVIDD YHDFVGTFEY WWTHGLISDD
110 120 130 140 150
TYQKLQLACE FDSAEHESEA CNKINNVAEA EEGLIDAYSI YTPTCKKTSL
160 170 180 190 200
HRRRLIKGRR PWLPRGYDPC TEQYSTKYYN LPEVQKAFRA NVTGIPYSWT
210 220 230 240 250
ACSDVLSDHW KDSPRSMLPI YRELIAAGIR IWVFSGDADS VVPLTATRYS
260 270 280 290 300
IDALYLPTVT NWYPWYDEEE VAGWCQVYKG LTLVTIRGAG HEVPLHRPQQ
310 320
ALKLFEHFLQ DKPMPRPAHS IQSF
Length:324
Mass (Da):37,408
Last modified:November 1, 1997 - v1
Checksum:i70F081D6B9723A60
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78876 mRNA. Translation: CAB58992.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78876 mRNA. Translation: CAB58992.1 .

3D structure databases

ProteinModelPortali P55747.
SMRi P55747. Positions 2-145, 167-315.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei P55747.

Gene expression databases

Genevestigatori P55747.

Family and domain databases

Gene3Di 3.40.50.1820. 1 hit.
InterProi IPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view ]
PANTHERi PTHR11802. PTHR11802. 1 hit.
Pfami PF00450. Peptidase_S10. 1 hit.
[Graphical view ]
PRINTSi PR00724. CRBOXYPTASEC.
SUPFAMi SSF53474. SSF53474. 1 hit.
PROSITEi PS00560. CARBOXYPEPT_SER_HIS. 1 hit.
PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The expression of serine carboxypeptidases during maturation and germination of the barley grain."
    Dal Degan F., Rocher A., Cameron-Mills V., von Wettstein D.
    Proc. Natl. Acad. Sci. U.S.A. 91:8209-8213(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
    Strain: cv. Alexis.
    Tissue: Grain.

Entry informationi

Entry nameiCBP21_HORVU
AccessioniPrimary (citable) accession number: P55747
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 1, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3