Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P55653

- GABD_RHISN

UniProt

P55653 - GABD_RHISN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable succinate-semialdehyde dehydrogenase [NADP(+)]

Gene

gabD

Organism
Rhizobium sp. (strain NGR234)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the NADP+ dependent oxidation of succinate semialdehyde to succinate.By similarity

Catalytic activityi

Succinate semialdehyde + NADP+ + H2O = succinate + NADPH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei263 – 2631Proton acceptorPROSITE-ProRule annotation
Binding sitei264 – 2641NADP; via carbonyl oxygenBy similarity
Active sitei297 – 2971NucleophilePROSITE-ProRule annotation
Binding sitei394 – 3941NADPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi163 – 1642NADPBy similarity
Nucleotide bindingi187 – 1904NADPBy similarity
Nucleotide bindingi241 – 2422NADPBy similarity

GO - Molecular functioni

  1. succinate-semialdehyde dehydrogenase [NAD(P)+] activity Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciSFRE394:GBYN-6214-MONOMER.
UniPathwayiUPA00733.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable succinate-semialdehyde dehydrogenase [NADP(+)] (EC:1.2.1.79)
Short name:
SSDH
Gene namesi
Name:gabD
Ordered Locus Names:NGR_a01630
ORF Names:y4sJ
Encoded oniPlasmid sym pNGR234a0 Publication
OrganismiRhizobium sp. (strain NGR234)
Taxonomic identifieri394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001054: Plasmid sym pNGR234a

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 491491Probable succinate-semialdehyde dehydrogenase [NADP(+)]PRO_0000056573Add
BLAST

Proteomic databases

PRIDEiP55653.

Interactioni

Protein-protein interaction databases

STRINGi394.NGR_a01630.

Structurei

3D structure databases

ProteinModelPortaliP55653.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271509.
KOiK00135.
OMAiVEWTRYY.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR010102. Succ_semiAld_DH.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
TIGRFAMsiTIGR01780. SSADH. 1 hit.
PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P55653-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTLTSALTRH LKCPELFRNL ANEPHPSVAG QRQRFSVFNP STGELLAEVP
60 70 80 90 100
DMGAADAHAA IERADAAQEP WSGLTARARS DILWKWHRFI LEHSDDLAAI
110 120 130 140 150
LTAEMGKPLG EAKSEVQHAA AYLQWYAEEA NRIYGETISA PSTDRRMLVI
160 170 180 190 200
KQPIGVVGAI TPWNFPASMV ARKISPALAA GCTVVLKPAE QTPLVAGAMF
210 220 230 240 250
ALAKLAGFPD GVLNLVYASE GDAIGRELCT NPKVRKISFT GSTEVGRLLM
260 270 280 290 300
RQCSDQIKRI SFELGGNAPF IVFDDADIDA AVDGAIQAKF RNAGQTCVSA
310 320 330 340 350
NRIYVQSGVY AEFAEKFTER VRTLKVGDGF DPNVAIGPLI NQEALKKIEL
360 370 380 390 400
HISDAVQKGA RVRSGGRRTG SSGTFFEPTV VTDVSKTMRL AEEETFGPLA
410 420 430 440 450
PLLRFDDADH VVREANDTIY GLAAYFYASN LKRVWRVAEA LEYGMVGINT
460 470 480 490
GRMSSEAAPF GGVKQSGIGR EGSRHGLEDY LDMKYLCVGG L
Length:491
Mass (Da):53,254
Last modified:November 1, 1997 - v1
Checksum:iFC54C5DF7B4D1B14
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00090 Genomic DNA. Translation: AAB91849.1.
PIRiS43963.
RefSeqiNP_444062.1. NC_000914.2.
WP_010875199.1. NC_000914.2.

Genome annotation databases

EnsemblBacteriaiAAB91849; AAB91849; NGR_a01630.
GeneIDi962447.
KEGGirhi:NGR_a01630.
PATRICi32301035. VBIRhiSp122450_0153.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00090 Genomic DNA. Translation: AAB91849.1 .
PIRi S43963.
RefSeqi NP_444062.1. NC_000914.2.
WP_010875199.1. NC_000914.2.

3D structure databases

ProteinModelPortali P55653.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 394.NGR_a01630.

Proteomic databases

PRIDEi P55653.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB91849 ; AAB91849 ; NGR_a01630 .
GeneIDi 962447.
KEGGi rhi:NGR_a01630.
PATRICi 32301035. VBIRhiSp122450_0153.

Phylogenomic databases

eggNOGi COG1012.
HOGENOMi HOG000271509.
KOi K00135.
OMAi VEWTRYY.
OrthoDBi EOG6BS8QW.

Enzyme and pathway databases

UniPathwayi UPA00733 .
BioCyci SFRE394:GBYN-6214-MONOMER.

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR010102. Succ_semiAld_DH.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
TIGRFAMsi TIGR01780. SSADH. 1 hit.
PROSITEi PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular basis of symbiosis between Rhizobium and legumes."
    Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A., Perret X.
    Nature 387:394-401(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.

Entry informationi

Entry nameiGABD_RHISN
AccessioniPrimary (citable) accession number: P55653
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 1, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. Rhizobium plasmid pNGR234a
    Rhizobium plasmid pNGR234a: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3