Reviewed, UniProtKB/Swiss-Prot P55539 (ISPA_RHISN)

Names and origin

Protein names

Recommended name:
    Probable geranyltranstransferase
    EC=2.5.1.10
Alternative name(s):
    Farnesyl-diphosphate synthase
      Short name=FPP synthase

Gene names

ORF Names:

y4kU

Encoded on

Plasmid sym pNGR234a

Organism

Rhizobium sp. (strain NGR234)

Taxonomic identifier

394 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the FPP/GGPP synthetase family.

Ontologies

Keywords
Biological process	Isoprene biosynthesis
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Plasmid
Gene Ontology (GO)
Biological process	isoprenoid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	geranyltranstransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 332	332	Probable geranyltranstransferase		PRO_0000123990

Sequences

	Sequence		Length	Mass (Da)
	P55539-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: EE68C1547449AA87	FASTA	332	34,689
	10 20 30 40 50 60 MQTGSTLHDD RTSVSALGGL GARARGASGR LLPEIWMQNG AKRVEQALAR LLCAEDHGET 70 80 90 100 110 120 ELMAAMRYAT LHGGKRTRAL LCLAAGALAD TPAHILDDVG AAIEMMHACT LVHDDLPAMD 130 140 150 160 170 180 DDVLRRGLPT VHVKFGEATA ILVGDALQAH AFLTLASLDA PGDNRIALVR ELAQAVSAEG 190 200 210 220 230 240 AAGGQAMDLS LVGKHVELDR IVAMHRMKCG ALVRASVRMG ALCAIAEDAA DATLYCALDH 250 260 270 280 290 300 YSACFGLALQ VVDDILDATA DTATLGKTPG KDAAAQKPTC ASIMGLQAAR QFALDLLCEA 310 320 330 GEAIAPLGPR AERLAQMLQR ASAYLFKHAP SA

References

[1]

"Molecular basis of symbiosis between Rhizobium and legumes." Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A., Perret X. Nature 387:394-401(1997) [PubMed: 9163424] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Rhizobium sp. strain NGR234 possesses a remarkable number of secretion systems." Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A., Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A., Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A., Broughton W.J., Perret X., Strittmatter A.W., Streit W.R. Appl. Environ. Microbiol. 75:4035-4045(2009) [PubMed: 19376903] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00090 Genomic DNA. Translation: AAB91752.1.
PIR	T10875.
RefSeq	NP_443950.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	962353.
Family and domain databases
InterPro	IPR000092. Polyprenyl_synt. IPR017446. Polyprenyl_synth-rel. IPR008949. Terpenoid_synth. [Graphical view]
Gene3D	G3DSA:1.10.600.10. Terpenoid_synth. 1 hit.
PANTHER	PTHR12001. Polyprenyl_synt. 1 hit.
Pfam	PF00348. polyprenyl_synt. 1 hit. [Graphical view]
PROSITE	PS00723. POLYPRENYL_SYNTHET_1. 1 hit. PS00444. POLYPRENYL_SYNTHET_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ISPA_RHISN

Accession

Primary (citable) accession number: P55539

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	July 7, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)