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Protein

Mannose-1-phosphate guanylyltransferase

Gene

noeJ

Organism
Rhizobium sp. (strain NGR234)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-KW
  2. mannose-1-phosphate guanylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. nodulation Source: UniProtKB-KW
  2. polysaccharide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Nodulation

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSFRE394:GBYN-6089-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Mannose-1-phosphate guanylyltransferase (EC:2.7.7.13)
Alternative name(s):
GDP-mannose pyrophosphorylase
Short name:
GMP
Short name:
GMPP
Gene namesi
Name:noeJ
Ordered Locus Names:NGR_a00380
ORF Names:y4aJ
Encoded oniPlasmid sym pNGR234a0 Publication
OrganismiRhizobium sp. (strain NGR234)
Taxonomic identifieri394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001054 Componenti: Plasmid sym pNGR234a

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 512512Mannose-1-phosphate guanylyltransferasePRO_0000194263Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi394.NGR_a00380.

Structurei

3D structure databases

ProteinModelPortaliP55357.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0662.
HOGENOMiHOG000153549.
KOiK00971.
OMAiTETHPTS.
OrthoDBiEOG6X3W6T.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
3.90.550.10. 1 hit.
InterProiIPR006375. Man1P_GuaTrfase/Man6P_Isoase.
IPR001538. Man6P_isomerase-2_C.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF01050. MannoseP_isomer. 1 hit.
PF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51182. SSF51182. 1 hit.
SSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01479. GMP_PMI. 1 hit.

Sequencei

Sequence statusi: Complete.

P55357-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSHPLMRLL RSRHTVMKLP SNAIKNDTML PKIIPAIMAG GRGTRLWPLS
60 70 80 90 100
RATAAKQFLK LIGEETLFQD TLKRVSDAKV YGAPLVITNE EFRFLVAEQA
110 120 130 140 150
RELGVTLSSI VLEPVPRNTA AAVAVAARIV ADRFGEDALL LVLPSDHAIT
160 170 180 190 200
VDDTYKKCVR SACIAAAEGK LVTFGIQPTW PATGYGYIER GTYLGKDVHA
210 220 230 240 250
VQCFVEKPSL EKAAALLETG NYYWNSGMFL FQAASIIAEL EEHAPDVLSA
260 270 280 290 300
VHAAVRGSTV DADFIRLAPE SFSQAPSISI DYALMEKTAN AAVVCSDFAW
310 320 330 340 350
SDLGSWDAVW KNEEQNADGN VLKGNVTACN TKNSLVLSHT AHLAVQGMDG
360 370 380 390 400
VAVIASEDAV FVGRLEEAHE IGNLVKRLAA DENTARLTEL HPTLIRPWGG
410 420 430 440 450
YTTMLNGDRF QVRRLFVRPG KMLSLHKHFH RSEHWICVKG TAEVTIEDRV
460 470 480 490 500
TILHENQSIY IPEGAIHRLG NPGKIMLELV EIQTGAYLGE DDIIRVADES
510
RNEMPDSRRT GP
Length:512
Mass (Da):56,213
Last modified:November 1, 1997 - v1
Checksum:i6D89C7C4D7F61FFE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00090 Genomic DNA. Translation: AAB91607.1.
RefSeqiNP_443769.1. NC_000914.2.
WP_010875080.1. NC_000914.2.

Genome annotation databases

EnsemblBacteriaiAAB91607; AAB91607; NGR_a00380.
GeneIDi962255.
KEGGirhi:NGR_a00380.
PATRICi32300801. VBIRhiSp122450_0036.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00090 Genomic DNA. Translation: AAB91607.1.
RefSeqiNP_443769.1. NC_000914.2.
WP_010875080.1. NC_000914.2.

3D structure databases

ProteinModelPortaliP55357.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi394.NGR_a00380.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB91607; AAB91607; NGR_a00380.
GeneIDi962255.
KEGGirhi:NGR_a00380.
PATRICi32300801. VBIRhiSp122450_0036.

Phylogenomic databases

eggNOGiCOG0662.
HOGENOMiHOG000153549.
KOiK00971.
OMAiTETHPTS.
OrthoDBiEOG6X3W6T.

Enzyme and pathway databases

BioCyciSFRE394:GBYN-6089-MONOMER.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
3.90.550.10. 1 hit.
InterProiIPR006375. Man1P_GuaTrfase/Man6P_Isoase.
IPR001538. Man6P_isomerase-2_C.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF01050. MannoseP_isomer. 1 hit.
PF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51182. SSF51182. 1 hit.
SSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01479. GMP_PMI. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Molecular basis of symbiosis between Rhizobium and legumes."
    Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A., Perret X.
    Nature 387:394-401(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.

Entry informationi

Entry nameiNOEJ_RHISN
AccessioniPrimary (citable) accession number: P55357
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 29, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. Rhizobium plasmid pNGR234a
    Rhizobium plasmid pNGR234a: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.