Reviewed, UniProtKB/Swiss-Prot P55357 (NOEJ_RHISN)

Names and origin

Protein names

Recommended name:
    Mannose-1-phosphate guanylyltransferase
    EC=2.7.7.13
Alternative name(s):
    GDP-mannose pyrophosphorylase
      Short name=GMPP
      Short name=GMP

Gene names

Name:	noeJ
Ordered Locus Names:	NGR_a00380
ORF Names:	y4aJ

Encoded on

Plasmid sym pNGR234a

Organism

Rhizobium sp. (strain NGR234) [Complete proteome] [HAMAP]

Taxonomic identifier

394 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	512 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.
Sequence similarities	Belongs to the mannose-6-phosphate isomerase type 2 family.

Ontologies

Keywords
Biological process	Nodulation
Ligand	GTP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: InterPro nodulation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW mannose-1-phosphate guanylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 512	512	Mannose-1-phosphate guanylyltransferase		PRO_0000194263

Sequences

	Sequence		Length	Mass (Da)
	P55357-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 6D89C7C4D7F61FFE	FASTA	512	56,213
	10 20 30 40 50 60 MNSHPLMRLL RSRHTVMKLP SNAIKNDTML PKIIPAIMAG GRGTRLWPLS RATAAKQFLK 70 80 90 100 110 120 LIGEETLFQD TLKRVSDAKV YGAPLVITNE EFRFLVAEQA RELGVTLSSI VLEPVPRNTA 130 140 150 160 170 180 AAVAVAARIV ADRFGEDALL LVLPSDHAIT VDDTYKKCVR SACIAAAEGK LVTFGIQPTW 190 200 210 220 230 240 PATGYGYIER GTYLGKDVHA VQCFVEKPSL EKAAALLETG NYYWNSGMFL FQAASIIAEL 250 260 270 280 290 300 EEHAPDVLSA VHAAVRGSTV DADFIRLAPE SFSQAPSISI DYALMEKTAN AAVVCSDFAW 310 320 330 340 350 360 SDLGSWDAVW KNEEQNADGN VLKGNVTACN TKNSLVLSHT AHLAVQGMDG VAVIASEDAV 370 380 390 400 410 420 FVGRLEEAHE IGNLVKRLAA DENTARLTEL HPTLIRPWGG YTTMLNGDRF QVRRLFVRPG 430 440 450 460 470 480 KMLSLHKHFH RSEHWICVKG TAEVTIEDRV TILHENQSIY IPEGAIHRLG NPGKIMLELV 490 500 510 EIQTGAYLGE DDIIRVADES RNEMPDSRRT GP

References

[1]

"Molecular basis of symbiosis between Rhizobium and legumes." Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A., Perret X. Nature 387:394-401(1997) [PubMed: 9163424] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Rhizobium sp. strain NGR234 possesses a remarkable number of secretion systems." Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A., Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A., Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A., Broughton W.J., Perret X., Strittmatter A.W., Streit W.R. Appl. Environ. Microbiol. 75:4035-4045(2009) [PubMed: 19376903] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00090 Genomic DNA. Translation: AAB91607.1.
RefSeq	NP_443769.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	962255.
GenomeReviews	Gene locus NGR_a00380 in contig U00090_GR.
Organism-specific databases
CMR	Search...
Family and domain databases
InterPro	IPR006375. Man1P_GuaTrfase/Man6P_Isoase. IPR001538. Man6P_isomerase-2_C. IPR005835. NTP_transferase. IPR014710. RmlC-like_jellyroll. [Graphical view]
Gene3D	G3DSA:2.60.120.10. RmlC-like_jellyroll. 1 hit.
Pfam	PF01050. MannoseP_isomer. 1 hit. PF00483. NTP_transferase. 1 hit. [Graphical view]
ProDom	PD002664. Man6P_isomerII. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01479. GMP_PMI. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NOEJ_RHISN

Accession

Primary (citable) accession number: P55357

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	September 22, 2009
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)