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Protein

Phosphomannomutase

Gene

noeK

Organism
Rhizobium sp. (strain NGR234)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

Cofactori

Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011Phosphoserine intermediateBy similarity
Metal bindingi101 – 1011Magnesium; via phosphate groupBy similarity
Metal bindingi242 – 2421MagnesiumBy similarity
Metal bindingi244 – 2441MagnesiumBy similarity
Metal bindingi246 – 2461MagnesiumBy similarity

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. phosphomannomutase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. nodulation Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Nodulation

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3298-MONOMER.
SFRE394:GBYN-6090-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphomannomutase (EC:5.4.2.8)
Short name:
PMM
Gene namesi
Name:noeK
Ordered Locus Names:NGR_a00390
ORF Names:y4aI
Encoded oniPlasmid sym pNGR234a0 Publication
OrganismiRhizobium sp. (strain NGR234)
Taxonomic identifieri394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001054 Componenti: Plasmid sym pNGR234a

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 474474PhosphomannomutasePRO_0000147833Add
BLAST

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi394.NGR_a00390.

Structurei

3D structure databases

ProteinModelPortaliP55356.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphohexose mutase family.Curated

Phylogenomic databases

eggNOGiCOG1109.
HOGENOMiHOG000066295.
KOiK01840.
OMAiPVSCNTA.
OrthoDBiEOG6TFCNH.

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 2 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P55356-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPKFGTSGL RGLATELVGS VSALYATAFS RMLLDRGRVA PGATVLVGRD
60 70 80 90 100
FRDSSSEIAA ICMAALARAG MVPVDCGGLP TPALALYGRK LGAASLMITG
110 120 130 140 150
SHIPADRNGI KFYLPDGEIN KADEQAITAL AEQLSADADA TRVECGRGAD
160 170 180 190 200
HSSEATDFYI QRYETLLPKS GLKGLKIGLY QHSSVARDIL TTILEGHGAN
210 220 230 240 250
VVPVGRSEVF IPVDTEAISA ATCKMLAAWA KEFAFDAIVS SDADADRPLL
260 270 280 290 300
TDETGTPLRG DLLGLICARL LEAKLIATPI TSNSGIEAAS GVEVVRTRVG
310 320 330 340 350
SPYVIAAMTE AVARGKQRVM GFEANGGVML GSNFSFGGAS LPALPTRDCV
360 370 380 390 400
LPIIAALHMA VEAKTPLSGI VAMHRLPVAL SGRIENYPFD RSDALVAFLK
410 420 430 440 450
ASKANVSHLF SRIGRVAGTD DVDGLRLTFE GGRILHIRPS GNAPELRCYV
460 470
EADDPDAAEH LLAQGLAVLN SSMV
Length:474
Mass (Da):49,671
Last modified:October 31, 1997 - v1
Checksum:i6965310CEA96A22B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00090 Genomic DNA. Translation: AAB91606.1.
RefSeqiNP_443768.1. NC_000914.2.
WP_010875081.1. NC_000914.2.

Genome annotation databases

EnsemblBacteriaiAAB91606; AAB91606; NGR_a00390.
GeneIDi962306.
KEGGirhi:NGR_a00390.
PATRICi32300803. VBIRhiSp122450_0037.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00090 Genomic DNA. Translation: AAB91606.1.
RefSeqiNP_443768.1. NC_000914.2.
WP_010875081.1. NC_000914.2.

3D structure databases

ProteinModelPortaliP55356.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi394.NGR_a00390.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB91606; AAB91606; NGR_a00390.
GeneIDi962306.
KEGGirhi:NGR_a00390.
PATRICi32300803. VBIRhiSp122450_0037.

Phylogenomic databases

eggNOGiCOG1109.
HOGENOMiHOG000066295.
KOiK01840.
OMAiPVSCNTA.
OrthoDBiEOG6TFCNH.

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3298-MONOMER.
SFRE394:GBYN-6090-MONOMER.

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 2 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular basis of symbiosis between Rhizobium and legumes."
    Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A., Perret X.
    Nature 387:394-401(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NGR234.

Entry informationi

Entry nameiNOEK_RHISN
AccessioniPrimary (citable) accession number: P55356
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 1997
Last sequence update: October 31, 1997
Last modified: March 3, 2015
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. Rhizobium plasmid pNGR234a
    Rhizobium plasmid pNGR234a: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.