P55356 (NOEK_RHISN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphomannomutase
Short name=PMM
EC=5.4.2.8

Gene names

Name:	noeK
Ordered Locus Names:	NGR_a00390
ORF Names:	y4aI

Encoded on

Plasmid sym pNGR234a

Organism

Rhizobium sp. (strain NGR234) [Complete proteome] [HAMAP]

Taxonomic identifier

394 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › Sinorhizobium fredii group › Rhizobium fredii

Protein attributes

Sequence length	474 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Biological process	Nodulation
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro nodulation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphomannomutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 474	474	Phosphomannomutase		PRO_0000147833
Sites
	Active site	101	1	Phosphoserine intermediate By similarity
	Metal binding	101	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity

Sequences

	Sequence		Length	Mass (Da)
	P55356 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 6965310CEA96A22B	FASTA	474	49,671
	10 20 30 40 50 60 MGPKFGTSGL RGLATELVGS VSALYATAFS RMLLDRGRVA PGATVLVGRD FRDSSSEIAA 70 80 90 100 110 120 ICMAALARAG MVPVDCGGLP TPALALYGRK LGAASLMITG SHIPADRNGI KFYLPDGEIN 130 140 150 160 170 180 KADEQAITAL AEQLSADADA TRVECGRGAD HSSEATDFYI QRYETLLPKS GLKGLKIGLY 190 200 210 220 230 240 QHSSVARDIL TTILEGHGAN VVPVGRSEVF IPVDTEAISA ATCKMLAAWA KEFAFDAIVS 250 260 270 280 290 300 SDADADRPLL TDETGTPLRG DLLGLICARL LEAKLIATPI TSNSGIEAAS GVEVVRTRVG 310 320 330 340 350 360 SPYVIAAMTE AVARGKQRVM GFEANGGVML GSNFSFGGAS LPALPTRDCV LPIIAALHMA 370 380 390 400 410 420 VEAKTPLSGI VAMHRLPVAL SGRIENYPFD RSDALVAFLK ASKANVSHLF SRIGRVAGTD 430 440 450 460 470 DVDGLRLTFE GGRILHIRPS GNAPELRCYV EADDPDAAEH LLAQGLAVLN SSMV

References

[1]

"Molecular basis of symbiosis between Rhizobium and legumes." Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A., Perret X. Nature 387:394-401(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NGR234.

[2]

"Rhizobium sp. strain NGR234 possesses a remarkable number of secretion systems." Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A., Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A., Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A., Broughton W.J., Perret X., Strittmatter A.W., Streit W.R. Appl. Environ. Microbiol. 75:4035-4045(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NGR234.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00090 Genomic DNA. Translation: AAB91606.1.
RefSeq	NP_443768.1. NC_000914.2.
3D structure databases
ProteinModelPortal	P55356.
ModBase	Search...
Protein-protein interaction databases
STRING	394.NGR_a00390.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB91606; AAB91606; NGR_a00390.
GeneID	962306.
KEGG	rhi:NGR_a00390.
PATRIC	32300803. VBIRhiSp122450_0037.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HOG000066295.
KO	K01840.
OMA	MAMACAK.
ProtClustDB	CLSK784548.
Family and domain databases
Gene3D	3.40.120.10. 2 hits.
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. [Graphical view]
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NOEK_RHISN

Accession

Primary (citable) accession number: P55356

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program