P55334 (XYN1_HUMIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Endo-1,4-beta-xylanase 1
Short name=Xylanase 1
EC=3.2.1.8

Alternative name(s):
1,4-beta-D-xylan xylanohydrolase 1

Gene names

Name:

XYL1

Organism

Humicola insolens (Soft-rot fungus)

Taxonomic identifier

34413 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › mitosporic Ascomycota › Humicola

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Sequence similarities	Belongs to the glycosyl hydrolase 11 (cellulase G) family.

Ontologies

Keywords
Biological process	Xylan degradation
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological_process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Chain	20 – 227	208	Endo-1,4-beta-xylanase 1		PRO_0000008007
Sites
	Active site	121	1	Nucleophile By similarity
	Active site	212	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	P55334 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 5C2FF6ADCFEADA1F	FASTA	227	25,601
	10 20 30 40 50 60 MVSLKSVLAA ATAVSSAIAA PFDFVPRDNS TALQARQVTP NAEGWHNGYF YSWWSDGGGQ 70 80 90 100 110 120 VQYTNLEGSR YQVRWRNTGN FVGGKGWNPG TGRTINYGGY FNPQGNGYLA VYGWTRNPLV 130 140 150 160 170 180 EYYVIESYGT YNPGSQAQYK GTFYTDGDQY DIFVSTRYNQ PSIDGTRTFQ QYWSIRKNKR 190 200 210 220 VGGSVNMQNH FNAWQQHGMP LGQHYYQVVA TEGYQSSGES DIYVQTH

References

[1]	"A novel method for efficient expression cloning of fungal enzyme genes." Dalboege H., Hansen H.P.H. Mol. Gen. Genet. 243:253-260(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	X76047 mRNA. Translation: CAA53632.1.
PIR	S43919.
3D structure databases
ProteinModelPortal	P55334.
SMR	P55334. Positions 37-224.
ModBase	Search...
Protein family/group databases
CAZy	GH11. Glycoside Hydrolase Family 11.
mycoCLAP	XYN11A_HUMIN.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00114.
Family and domain databases
Gene3D	2.60.120.180. 1 hit.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR001137. Glyco_hydro_11. IPR013319. Glyco_hydro_11/12. IPR018208. Glyco_hydro_11_AS. [Graphical view]
Pfam	PF00457. Glyco_hydro_11. 1 hit. [Graphical view]
PRINTS	PR00911. GLHYDRLASE11.
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit.
PROSITE	PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit. PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYN1_HUMIN

Accession

Primary (citable) accession number: P55334
Secondary accession number(s): Q12625

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	April 3, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program