Reviewed, UniProtKB/Swiss-Prot P55308 (CATA2_HORVU)

Names and origin

Protein names

Recommended name:
    Catalase isozyme 2
    EC=1.11.1.6

Gene names

Name:

CAT2

Organism

Hordeum vulgare (Barley)

Taxonomic identifier

4513 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Hordeum

Protein attributes

Sequence length	494 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H(2)O(2) = O(2) + 2 H(2)O.
Cofactor	Heme group By similarity.
Subunit structure	Homotetramer By similarity.
Subcellular location	PeroxisomeBy similarity. GlyoxysomeBy similarity.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Glyoxysome Peroxisome
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	glyoxysome Inferred from electronic annotation. Source: UniProtKB-KW peroxisome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 494	494	Catalase isozyme 2		PRO_0000084942
Sites
	Active site	65	1	By similarity
	Active site	138	1	By similarity
	Metal binding	348	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P55308-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 67E3CF2AD02E542E	FASTA	494	56,913
	10 20 30 40 50 60 MDPCKFRPSS SFDTKTTTTN AGQPVWNDNE ALTVGPRGPI LLEDYHLLEK IAHFARERIP 70 80 90 100 110 120 ERVVHARGAS AKGFFECTHD VTGLTCADFL RAPGARTPVI VRFSTVIHER GSPETIRDPR 130 140 150 160 170 180 GFAVKFYTRE GNWDLLGNNF PVFFIRDGIK FPDVIHAFKP NPKSHVQEYW RVFDFLSHHP 190 200 210 220 230 240 ESLHTFFFLF DDVGIPTDYR HMDGFGVNTY TFVSRAGKSH YVKFHWRPTC GVSCLMDDEA 250 260 270 280 290 300 TLVGGKNHSH ATQDLYDSID AGNFPEWKLF VQVIDPDEED RFDFDPLDDT KTWPEDLVPL 310 320 330 340 350 360 QPVGRLVLDR NVDNFFNENE QLAFGPGLVV PGIYYSDDKM LQCRVFAYAD TQRYRLGPNY 370 380 390 400 410 420 LMLPVNAPKC GFKNNHYDGA MNFMHRDEEV DYYPSRHAPL RHAEPASFPV PTRPVVGKRE 430 440 450 460 470 480 KTRIKKENDF VQPGERYRSW APDRQDRFVR RFSDALAHPK VSHELRVIWI DFLSKCDKSC 490 GMKVANRLNV KPSM

References

[1]	"Molecular cloning, characterization and expression analysis of two catalase isozyme genes in barley." Skadsen R.W., Schulze-Lefert P., Herbst J.M. Plant Mol. Biol. 29:1005-1014(1995) [PubMed: 8555444] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Morex.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U20778 mRNA. Translation: AAA96948.1.
PIR	S62697.
3D structure databases
HSSP	HSSP built from PDB template 1M7S based on UniProtKB P46206.
ModBase	Search...
Organism-specific databases
Gramene	P55308.
Family and domain databases
InterPro	IPR002226. Catalase. IPR011614. Catalase_N. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA2_HORVU

Accession

Primary (citable) accession number: P55308

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	November 25, 2008
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)