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P55305 (CATA_EMENI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Catalase A

EC=1.11.1.6
Alternative name(s):
Spore-specific catalase
Gene names
Name:catA
ORF Names:AN8637
OrganismEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) [Reference proteome]
Taxonomic identifier227321 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length744 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activity

2 H2O2 = O2 + 2 H2O.

Cofactor

Heme group.

Developmental stage

Sporulation-specific.

Sequence similarities

Belongs to the catalase family.

Sequence caution

The sequence AAC49254.1 differs from that shown. Reason: Frameshift at positions 583 and 592.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 744744Catalase A
PRO_0000084921

Sites

Active site931 By similarity
Active site1661 By similarity
Metal binding3801Iron (heme axial ligand) By similarity

Experimental info

Sequence conflict5821Q → A in AAC49254. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P55305 [UniParc].

Last modified May 26, 2009. Version 2.
Checksum: 3933E190CCBB0713

FASTA74483,990
        10         20         30         40         50         60 
MATSITAGLQ KAQQAVQDTA TKNKKIVDIS HDTVNVHTDQ EQRTDFGVAI TDPDHWLRVT 

        70         80         90        100        110        120 
NETHSGPSLL EDHIARERIH RFDHERIPER VVHARGTGAY GNFTLKESIE DLTYAGVLTD 

       130        140        150        160        170        180 
TSRNTPVFVR FSTVQGSRGS ADTVRDVRGF AVKFYTDEGN WDIVGNNIPV FFIQDAIKFP 

       190        200        210        220        230        240 
DFVHAVKPEP HNEVPQAQTA HNNFWDFVYL HPEATHMFMW AMSDRAIPRS YRMMQGFGVN 

       250        260        270        280        290        300 
TFSLVNKEGK RHFVKFHWIP HLGVHSLVWD EALKLAGQDP DFHRKDLMEA IDNKAYPKWD 

       310        320        330        340        350        360 
FAIQAIPEED QDKFEFDIFD ATKVWPEEQV PLRVVGELEL NRNIDEFFPE TEQVAFCTSH 

       370        380        390        400        410        420 
IVPGIDFSDD PLLQGRNFSY QDTQISRLGV NWEEIPINRP VCPFLNHNRD GAKRHRITKG 

       430        440        450        460        470        480 
TVNYWPNRFE ANPPASDKGF KSHPAPITGR KRRDLTPKFK EYHNQAQLFY NSLSEVEKVH 

       490        500        510        520        530        540 
VKKAFSFELD HCDDPIVYER LAGQRLAEID LPLAQAVAEM VGAPIPTKAL RDNHGKTSVR 

       550        560        570        580        590        600 
LSQFDFTPKA PGIISRRIAI IIGDGYDKIA FNGMKAAILA AQALPFVIGT KRSAIYAQGE 

       610        620        630        640        650        660 
DKNSSKGVIP DHMYDGMRST MFDATFIPGG SHIETLQKNG QIRYWIAETF GHLKALGAMG 

       670        680        690        700        710        720 
EAAQLVKEVL GNVMGVQIAG ADSAEPVEWY GVVTARGPES AESLSEGFKV LKDAGDFTSK 

       730        740 
FFYQISQHRN WQRELDGLAS TVAF 

« Hide

References

« Hide 'large scale' references
[1]"catA, a new Aspergillus nidulans gene encoding a developmentally regulated catalase."
Navarro R.E., Stringer M.A., Hansberg W., Timberlake W.E., Aguirre J.
Curr. Genet. 29:352-359(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: FGSC 26.
[2]"Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae."
Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S., Braus G.H. expand/collapse author list , Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L., Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.
Nature 438:1105-1115(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
[3]"The 2008 update of the Aspergillus nidulans genome annotation: a community effort."
Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J., Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M., Estrada C.G. expand/collapse author list , Geysens S., Goldman G., de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B., van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.
Fungal Genet. Biol. 46:S2-13(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U37803 Genomic DNA. Translation: AAC49254.1. Frameshift.
AACD01000158 Genomic DNA. Translation: EAA60671.1.
BN001303 Genomic DNA. Translation: CBF78282.1.
PIRS68115.
RefSeqXP_681906.1. XM_676814.1.

3D structure databases

ProteinModelPortalP55305.
SMRP55305. Positions 44-744.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING162425.CADANIAP00006410.

Protein family/group databases

PeroxiBase5213. AniKat01.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANIAT00006410; CADANIAP00006410; CADANIAG00006410.
GeneID2868532.
KEGGani:AN8637.2.

Phylogenomic databases

eggNOGCOG0753.
HOGENOMHOG000087851.
KOK03781.
OMAHTEATHM.
OrthoDBEOG7K9KBN.

Family and domain databases

Gene3D2.40.180.10. 1 hit.
InterProIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024712. Catalase_clade2.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERPTHR11465. PTHR11465. 1 hit.
PfamPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFPIRSF038927. Catalase_clade2. 1 hit.
PRINTSPR00067. CATALASE.
SMARTSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMSSF56634. SSF56634. 1 hit.
PROSITEPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCATA_EMENI
AccessionPrimary (citable) accession number: P55305
Secondary accession number(s): C8VAD2, Q5ASU3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: May 26, 2009
Last modified: January 22, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families