Reviewed, UniProtKB/Swiss-Prot P55305 (CATA_EMENI)

Names and origin

Protein names

Recommended name:
    Catalase A
    EC=1.11.1.6
Alternative name(s):
    Spore-specific catalase

Gene names

Name:

catA

Organism

Emericella nidulans (Aspergillus nidulans)

Taxonomic identifier

162425 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › Emericella

Protein attributes

Sequence length	744 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H(2)O(2) = O(2) + 2 H(2)O.
Cofactor	Heme group.
Developmental stage	Sporulation-specific.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide Sporulation
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 744	744	Catalase A		PRO_0000084921
Sites
	Active site	93	1	By similarity
	Active site	166	1	By similarity
	Metal binding	380	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P55305-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 4B4D0B7C8EC8DFFA	FASTA	744	84,064
	10 20 30 40 50 60 MATSITAGLQ KAQQAVQDTA TKNKKIVDIS HDTVNVHTDQ EQRTDFGVAI TDPDHWLRVT 70 80 90 100 110 120 NETHSGPSLL EDHIARERIH RFDHERIPER VVHARGTGAY GNFTLKESIE DLTYAGVLTD 130 140 150 160 170 180 TSRNTPVFVR FSTVQGSRGS ADTVRDVRGF AVKFYTDEGN WDIVGNNIPV FFIQDAIKFP 190 200 210 220 230 240 DFVHAVKPEP HNEVPQAQTA HNNFWDFVYL HPEATHMFMW AMSDRAIPRS YRMMQGFGVN 250 260 270 280 290 300 TFSLVNKEGK RHFVKFHWIP HLGVHSLVWD EALKLAGQDP DFHRKDLMEA IDNKAYPKWD 310 320 330 340 350 360 FAIQAIPEED QDKFEFDIFD ATKVWPEEQV PLRVVGELEL NRNIDEFFPE TEQVAFCTSH 370 380 390 400 410 420 IVPGIDFSDD PLLQGRNFSY QDTQISRLGV NWEEIPINRP VCPFLNHNRD GAKRHRITKG 430 440 450 460 470 480 TVNYWPNRFE ANPPASDKGF KSHPAPITGR KRRDLTPKFK EYHNQAQLFY NSLSEVEKVH 490 500 510 520 530 540 VKKAFSFELD HCDDPIVYER LAGQRLAEID LPLAQAVAEM VGAPIPTKAL RDNHGKTSVR 550 560 570 580 590 600 LSQFDFTPKA PGIISRRIAI IIGDGYDKIA FNGMKAAILA AASAPLRHWH QTSAIYAQGE 610 620 630 640 650 660 DKNSSKGVIP DHMYDGMRST MFDATFIPGG SHIETLQKNG QIRYWIAETF GHLKALGAMG 670 680 690 700 710 720 EAAQLVKEVL GNVMGVQIAG ADSAEPVEWY GVVTARGPES AESLSEGFKV LKDAGDFTSK 730 740 FFYQISQHRN WQRELDGLAS TVAF

References

[1]	"catA, a new Aspergillus nidulans gene encoding a developmentally regulated catalase." Navarro R.E., Stringer M.A., Hansberg W., Timberlake W.E., Aguirre J. Curr. Genet. 29:352-359(1996) [PubMed: 8598056] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: FGSC 26.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U37803 Genomic DNA. Translation: AAC49254.1.
PIR	S68115.
3D structure databases
HSSP	HSSP built from PDB template 1CF9 based on UniProtKB P21179.
ModBase	Search...
Family and domain databases
InterPro	IPR002226. Catalase. IPR010582. Catalase-rel. IPR011614. Catalase_N. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. PF06628. Catalase-rel. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_EMENI

Accession

Primary (citable) accession number: P55305

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	November 25, 2008
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)