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P55298

- MANC_PIRSP

UniProt

P55298 - MANC_PIRSP

Protein

Mannan endo-1,4-beta-mannosidase C

Gene

MANC

Organism
Piromyces sp.
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. cellulase activity Source: InterPro
    3. mannan endo-1,4-beta-mannosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. substituted mannan metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Protein family/group databases

    CAZyiCBM35. Carbohydrate-Binding Module Family 35.
    GH26. Glycoside Hydrolase Family 26.
    mycoCLAPiMAN26C_PIRSP.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Mannan endo-1,4-beta-mannosidase C (EC:3.2.1.78)
    Alternative name(s):
    1,4-beta-D-mannan mannanohydrolase C
    Beta-mannanase C
    Gene namesi
    Name:MANC
    OrganismiPiromyces sp.
    Taxonomic identifieri45796 [NCBI]
    Taxonomic lineageiEukaryotaFungiNeocallimastigomycotaNeocallimastigomycetesNeocallimastigalesNeocallimastigaceaePiromyces

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 569551Mannan endo-1,4-beta-mannosidase CPRO_0000012176Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP55298.
    SMRiP55298. Positions 532-569.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini21 – 139119CBM6PROSITE-ProRule annotationAdd
    BLAST
    Domaini489 – 52436CBM10 1Add
    BLAST
    Domaini533 – 56836CBM10 2Add
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi473 – 4775Poly-Asn
    Compositional biasi480 – 4867Poly-Asn

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 26 family.Curated
    Contains 1 CBM6 (carbohydrate binding type-6) domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Signal

    Family and domain databases

    Gene3Di2.60.120.260. 1 hit.
    3.20.20.80. 1 hit.
    3.90.1220.10. 2 hits.
    InterProiIPR002883. CBM10/Dockerin_dom.
    IPR005084. CMB_fam6.
    IPR009034. Dockerin_dom_fun.
    IPR022790. EndoGluc_H/Glyco_hydro_26.
    IPR008979. Galactose-bd-like.
    IPR000805. Glyco_hydro_26.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF02013. CBM_10. 2 hits.
    PF02156. Glyco_hydro_26. 1 hit.
    [Graphical view]
    PRINTSiPR00739. GLHYDRLASE26.
    SUPFAMiSSF49785. SSF49785. 1 hit.
    SSF51445. SSF51445. 1 hit.
    SSF64571. SSF64571. 2 hits.
    PROSITEiPS51175. CBM6. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P55298-1 [UniParc]FASTAAdd to Basket

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    MLTLTLLLYL SFITTVFSKK VIYEAENGKL DGVSKYNELQ GYSGTGYVGR    50
    FESAGNSVTV TVEVSQTGMY DMSIIYCGNM GQKINSLKIN GKNSGDITFP 100
    ENSSFEELNI GAVYLNSGEN TVSLVASWGW IWIDALVVND TPNVAKDVSP 150
    HINPTLVNPK AIPAAKKLYD FLRSNYGKRI LSGQVGGAGQ AGDEGQEIQR 200
    IQKATGKLPA VWNMDFIFES NDCTWRPENP DITEMAINWW KKYQGKGIMA 250
    AQWHWNIAGK TGDFAFYKKD TTFSIDNAVT EGTWEYEKII KDIDRVAGHI 300
    KKLQAVNMPL IWRPLHENDG DWFWWGNNPK SCAKLWKILY ERMVNYHGLN 350
    NLIWLWNGKN DANTPVDYID IIGVDIYAND HGPQTTAYNT HFDFYGGKKM 400
    VVLSENGRIP DIQQCVDQNA WWGYFQTWNS EFILQDSYHT DAQLKEYFTH 450
    KTVMNMDELP SFNVNSYEYQ SGNNNNNSSN NNNNNNSSEC FSIPLGYPCC 500
    KGNTVVYTDN DGDWGVENNE WCGIGNSSSA VVCWSEALGY PCCVSSSDVY 550
    YTDNDGEWGV ENGDWCGII 569
    Length:569
    Mass (Da):64,115
    Last modified:October 1, 1996 - v1
    Checksum:i19277764E18328B5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X97520 mRNA. Translation: CAA66134.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X97520 mRNA. Translation: CAA66134.1 .

    3D structure databases

    ProteinModelPortali P55298.
    SMRi P55298. Positions 532-569.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi CBM35. Carbohydrate-Binding Module Family 35.
    GH26. Glycoside Hydrolase Family 26.
    mycoCLAPi MAN26C_PIRSP.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.60.120.260. 1 hit.
    3.20.20.80. 1 hit.
    3.90.1220.10. 2 hits.
    InterProi IPR002883. CBM10/Dockerin_dom.
    IPR005084. CMB_fam6.
    IPR009034. Dockerin_dom_fun.
    IPR022790. EndoGluc_H/Glyco_hydro_26.
    IPR008979. Galactose-bd-like.
    IPR000805. Glyco_hydro_26.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF02013. CBM_10. 2 hits.
    PF02156. Glyco_hydro_26. 1 hit.
    [Graphical view ]
    PRINTSi PR00739. GLHYDRLASE26.
    SUPFAMi SSF49785. SSF49785. 1 hit.
    SSF51445. SSF51445. 1 hit.
    SSF64571. SSF64571. 2 hits.
    PROSITEi PS51175. CBM6. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evidence that the Piromyces gene family encoding endo-1,4-mannanases arose through gene duplication."
      Millward-Sadler S.J., Hall J., Black G.W., Hazlewood G.P., Gilbert H.J.
      FEMS Microbiol. Lett. 141:183-188(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiMANC_PIRSP
    AccessioniPrimary (citable) accession number: P55298
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3