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P55298 (MANC_PIRSP) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mannan endo-1,4-beta-mannosidase C

EC=3.2.1.78
Alternative name(s):
1,4-beta-D-mannan mannanohydrolase C
Beta-mannanase C
Gene names
Name:MANC
OrganismPiromyces sp.
Taxonomic identifier45796 [NCBI]
Taxonomic lineageEukaryotaFungiNeocallimastigomycotaNeocallimastigomycetesNeocallimastigalesNeocallimastigaceaePiromyces

Protein attributes

Sequence length569 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

Sequence similarities

Belongs to the glycosyl hydrolase 26 family.

Contains 2 CBM10 (carbohydrate binding type-10) domains.

Contains 1 CBM6 (carbohydrate binding type-6) domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 569551Mannan endo-1,4-beta-mannosidase C
PRO_0000012176

Regions

Domain21 – 139119CBM6
Domain489 – 52436CBM10 1
Domain533 – 56836CBM10 2
Compositional bias473 – 4775Poly-Asn
Compositional bias480 – 4867Poly-Asn

Sequences

Sequence LengthMass (Da)Tools
P55298 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 19277764E18328B5

FASTA56964,115
        10         20         30         40         50         60 
MLTLTLLLYL SFITTVFSKK VIYEAENGKL DGVSKYNELQ GYSGTGYVGR FESAGNSVTV 

        70         80         90        100        110        120 
TVEVSQTGMY DMSIIYCGNM GQKINSLKIN GKNSGDITFP ENSSFEELNI GAVYLNSGEN 

       130        140        150        160        170        180 
TVSLVASWGW IWIDALVVND TPNVAKDVSP HINPTLVNPK AIPAAKKLYD FLRSNYGKRI 

       190        200        210        220        230        240 
LSGQVGGAGQ AGDEGQEIQR IQKATGKLPA VWNMDFIFES NDCTWRPENP DITEMAINWW 

       250        260        270        280        290        300 
KKYQGKGIMA AQWHWNIAGK TGDFAFYKKD TTFSIDNAVT EGTWEYEKII KDIDRVAGHI 

       310        320        330        340        350        360 
KKLQAVNMPL IWRPLHENDG DWFWWGNNPK SCAKLWKILY ERMVNYHGLN NLIWLWNGKN 

       370        380        390        400        410        420 
DANTPVDYID IIGVDIYAND HGPQTTAYNT HFDFYGGKKM VVLSENGRIP DIQQCVDQNA 

       430        440        450        460        470        480 
WWGYFQTWNS EFILQDSYHT DAQLKEYFTH KTVMNMDELP SFNVNSYEYQ SGNNNNNSSN 

       490        500        510        520        530        540 
NNNNNNSSEC FSIPLGYPCC KGNTVVYTDN DGDWGVENNE WCGIGNSSSA VVCWSEALGY 

       550        560 
PCCVSSSDVY YTDNDGEWGV ENGDWCGII 

« Hide

References

[1]"Evidence that the Piromyces gene family encoding endo-1,4-mannanases arose through gene duplication."
Millward-Sadler S.J., Hall J., Black G.W., Hazlewood G.P., Gilbert H.J.
FEMS Microbiol. Lett. 141:183-188(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X97520 mRNA. Translation: CAA66134.1.

3D structure databases

ProteinModelPortalP55298.
SMRP55298. Positions 532-569.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyCBM35. Carbohydrate-Binding Module Family 35.
GH26. Glycoside Hydrolase Family 26.
mycoCLAPMAN26C_PIRSP.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.120.260. 1 hit.
3.20.20.80. 1 hit.
3.90.1220.10. 2 hits.
InterProIPR002883. CBM10/Dockerin_dom.
IPR005084. CMB_fam6.
IPR009034. Dockerin_dom.
IPR022790. EndoGluc_H/Glyco_hydro_26.
IPR008979. Galactose-bd-like.
IPR000805. Glyco_hydro_26.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF02013. CBM_10. 2 hits.
PF02156. Glyco_hydro_26. 1 hit.
[Graphical view]
PRINTSPR00739. GLHYDRLASE26.
SUPFAMSSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF64571. SSF64571. 2 hits.
PROSITEPS51175. CBM6. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMANC_PIRSP
AccessionPrimary (citable) accession number: P55298
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: December 11, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries