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Protein

Mannan endo-1,4-beta-mannosidase C

Gene

MANC

Organism
Piromyces sp.
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei317Proton donorPROSITE-ProRule annotation1
Active sitei405NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Protein family/group databases

CAZyiCBM35 Carbohydrate-Binding Module Family 35
GH26 Glycoside Hydrolase Family 26
mycoCLAPiMAN26C_PIRSP

Names & Taxonomyi

Protein namesi
Recommended name:
Mannan endo-1,4-beta-mannosidase C (EC:3.2.1.78)
Alternative name(s):
1,4-beta-D-mannan mannanohydrolase C
Beta-mannanase C
Gene namesi
Name:MANC
OrganismiPiromyces sp.
Taxonomic identifieri45796 [NCBI]
Taxonomic lineageiEukaryotaFungiFungi incertae sedisChytridiomycotaNeocallimastigomycetesNeocallimastigalesNeocallimastigaceaePiromyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000001217619 – 569Mannan endo-1,4-beta-mannosidase CAdd BLAST551

Proteomic databases

PRIDEiP55298

Structurei

3D structure databases

ProteinModelPortaliP55298
SMRiP55298
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 139CBM6PROSITE-ProRule annotationAdd BLAST119
Domaini163 – 457GH26PROSITE-ProRule annotationAdd BLAST295
Domaini489 – 525CBM10 1PROSITE-ProRule annotationAdd BLAST37
Domaini532 – 569CBM10 2PROSITE-ProRule annotationAdd BLAST38

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi473 – 477Poly-Asn5
Compositional biasi480 – 486Poly-Asn7

Sequence similaritiesi

Belongs to the glycosyl hydrolase 26 family.PROSITE-ProRule annotationCurated

Keywords - Domaini

Repeat, Signal

Family and domain databases

Gene3Di2.60.120.260, 1 hit
3.90.1220.10, 2 hits
InterProiView protein in InterPro
IPR002883 CBM10/Dockerin_dom
IPR005084 CMB_fam6
IPR009034 Dockerin_dom_fun_sf
IPR008979 Galactose-bd-like_sf
IPR022790 GH26_dom
IPR000805 Glyco_hydro_26
IPR017853 Glycoside_hydrolase_SF
PANTHERiPTHR40079 PTHR40079, 1 hit
PfamiView protein in Pfam
PF02013 CBM_10, 2 hits
PF16990 CBM_35, 1 hit
PF02156 Glyco_hydro_26, 1 hit
PRINTSiPR00739 GLHYDRLASE26
SUPFAMiSSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit
SSF64571 SSF64571, 2 hits
PROSITEiView protein in PROSITE
PS51763 CBM10, 2 hits
PS51175 CBM6, 1 hit
PS51764 GH26, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P55298-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTLTLLLYL SFITTVFSKK VIYEAENGKL DGVSKYNELQ GYSGTGYVGR
60 70 80 90 100
FESAGNSVTV TVEVSQTGMY DMSIIYCGNM GQKINSLKIN GKNSGDITFP
110 120 130 140 150
ENSSFEELNI GAVYLNSGEN TVSLVASWGW IWIDALVVND TPNVAKDVSP
160 170 180 190 200
HINPTLVNPK AIPAAKKLYD FLRSNYGKRI LSGQVGGAGQ AGDEGQEIQR
210 220 230 240 250
IQKATGKLPA VWNMDFIFES NDCTWRPENP DITEMAINWW KKYQGKGIMA
260 270 280 290 300
AQWHWNIAGK TGDFAFYKKD TTFSIDNAVT EGTWEYEKII KDIDRVAGHI
310 320 330 340 350
KKLQAVNMPL IWRPLHENDG DWFWWGNNPK SCAKLWKILY ERMVNYHGLN
360 370 380 390 400
NLIWLWNGKN DANTPVDYID IIGVDIYAND HGPQTTAYNT HFDFYGGKKM
410 420 430 440 450
VVLSENGRIP DIQQCVDQNA WWGYFQTWNS EFILQDSYHT DAQLKEYFTH
460 470 480 490 500
KTVMNMDELP SFNVNSYEYQ SGNNNNNSSN NNNNNNSSEC FSIPLGYPCC
510 520 530 540 550
KGNTVVYTDN DGDWGVENNE WCGIGNSSSA VVCWSEALGY PCCVSSSDVY
560
YTDNDGEWGV ENGDWCGII
Length:569
Mass (Da):64,115
Last modified:October 1, 1996 - v1
Checksum:i19277764E18328B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97520 mRNA Translation: CAA66134.1

Similar proteinsi

Entry informationi

Entry nameiMANC_PIRSP
AccessioniPrimary (citable) accession number: P55298
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

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