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Protein

Mannan endo-1,4-beta-mannosidase

Gene
N/A
Organism
Bacillus subtilis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

GO - Molecular functioni

  1. cellulase activity Source: InterPro
  2. mannan endo-1,4-beta-mannosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. substituted mannan metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH26. Glycoside Hydrolase Family 26.

Names & Taxonomyi

Protein namesi
Recommended name:
Mannan endo-1,4-beta-mannosidase (EC:3.2.1.78)
Alternative name(s):
1,4-beta-D-mannan mannanohydrolase
Beta-mannanase
OrganismiBacillus subtilis
Taxonomic identifieri1423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence AnalysisAdd
BLAST
Chaini25 – 360336Mannan endo-1,4-beta-mannosidasePRO_0000012171Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP55278.
SMRiP55278. Positions 25-360.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 26 family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR022790. EndoGluc_H/Glyco_hydro_26.
IPR000805. Glyco_hydro_26.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR016714. Mannan-1_4-b-mannosidase.
[Graphical view]
PfamiPF02156. Glyco_hydro_26. 1 hit.
[Graphical view]
PIRSFiPIRSF018168. Mannan-1_4-beta-mannosidase. 1 hit.
PRINTSiPR00739. GLHYDRLASE26.
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P55278-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKLAVCLS IVLLLLGAAS PISAHTVYPV NPNAQQTTKD IMNWLAHLPN
60 70 80 90 100
RSENRVMSGA FGGYSDVTFS MTEENRLKNA TGQSPAIYGC DYGRGWLETA
110 120 130 140 150
DITDTIDYCC NSSLISYWKS GGLPQVSLHL ANPAFPSGNY KTAISNSQYK
160 170 180 190 200
NILDPSTVEG KRLEALLSKI ADGLTQLKNQ GVTVLFRPLH EMNGEWFWWG
210 220 230 240 250
LTGYNQKDNE RISLYKELYK KIYRYMTETR GLDNLLWVYS PDANRDFKTD
260 270 280 290 300
FYPGSSYVDI TGLDAYFTDP YAISGYDEML SLKKPFAFAE TGPSGNIGSF
310 320 330 340 350
DYAAFINAIR QKYPQTTYFL TWDEQLSPAA NQGAQSLYQN SWTLNKGEIW
360
NGGSLTPIAE
Length:360
Mass (Da):40,295
Last modified:October 1, 1996 - v1
Checksum:i070B0EBCC0382383
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D37964 Genomic DNA. Translation: BAA07178.1.
PIRiS60268.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D37964 Genomic DNA. Translation: BAA07178.1.
PIRiS60268.

3D structure databases

ProteinModelPortaliP55278.
SMRiP55278. Positions 25-360.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH26. Glycoside Hydrolase Family 26.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR022790. EndoGluc_H/Glyco_hydro_26.
IPR000805. Glyco_hydro_26.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR016714. Mannan-1_4-b-mannosidase.
[Graphical view]
PfamiPF02156. Glyco_hydro_26. 1 hit.
[Graphical view]
PIRSFiPIRSF018168. Mannan-1_4-beta-mannosidase. 1 hit.
PRINTSiPR00739. GLHYDRLASE26.
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Cloning and sequencing of beta-mannanase gene from Bacillus subtilis NM-39."
    Mendoza N.S., Arai M., Sugimoto K., Ueda M., Kawaguchi T., Joson L.M.
    Biochim. Biophys. Acta 1243:552-554(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: NM-39.

Entry informationi

Entry nameiMANB2_BACIU
AccessioniPrimary (citable) accession number: P55278
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: January 7, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.