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Protein

Apolipoprotein C-IV

Gene

APOC4

Organism
Oryctolagus cuniculus (Rabbit)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May participate in lipoprotein metabolism.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Lipid transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Apolipoprotein C-IV
Short name:
Apo-CIV
Short name:
ApoC-IV
Alternative name(s):
Apolipoprotein C4
PARP
Gene namesi
Name:APOC4
OrganismiOryctolagus cuniculus (Rabbit)
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

HDL, Secreted, VLDL

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Add BLAST27
ChainiPRO_000000203828 – 124Apolipoprotein C-IVAdd BLAST97

Post-translational modificationi

Glycosylated; contains sialic acid. Present in up to five sialylated isoforms.

Keywords - PTMi

Glycoprotein

Expressioni

Tissue specificityi

Blood plasma, associated primarily with VLDL and HDL. Expressed mainly in the liver.

Family & Domainsi

Sequence similaritiesi

Belongs to the apolipoprotein C4 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOVERGENiHBG050550.
InParanoidiP55057.

Family and domain databases

InterProiIPR028120. APOC4.
[Graphical view]
PANTHERiPTHR32288. PTHR32288. 1 hit.
PfamiPF15119. APOC4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P55057-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLPRRGLRT LPSLCLYILV LVWVVACEPE GTPTPLPAPE ESRWSLVPSS
60 70 80 90 100
VKELVGPLLT RTRERWQWFW GPGALQGFVQ TYYDDHLRDL GPRAQAWLTS
110 120
SRDRLLNTAQ GLCPRLLCGD KDQD
Length:124
Mass (Da):14,113
Last modified:October 1, 1996 - v1
Checksum:iD4E42C51F078290C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39356 mRNA. Translation: AAC48513.1.
RefSeqiNP_001075834.1. NM_001082365.2.
UniGeneiOcu.2288.

Genome annotation databases

GeneIDi100009218.
KEGGiocu:100009218.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39356 mRNA. Translation: AAC48513.1.
RefSeqiNP_001075834.1. NM_001082365.2.
UniGeneiOcu.2288.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100009218.
KEGGiocu:100009218.

Organism-specific databases

CTDi346.

Phylogenomic databases

HOVERGENiHBG050550.
InParanoidiP55057.

Family and domain databases

InterProiIPR028120. APOC4.
[Graphical view]
PANTHERiPTHR32288. PTHR32288. 1 hit.
PfamiPF15119. APOC4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAPOC4_RABIT
AccessioniPrimary (citable) accession number: P55057
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 5, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.