Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Fatty acid-binding protein 9

Gene

Fabp9

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • acrosome assembly Source: RGD
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Lipid-binding

Enzyme and pathway databases

ReactomeiR-RNO-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty acid-binding protein 9
Alternative name(s):
15 kDa perforatorial protein
Short name:
PERF 15
Testis lipid-binding protein
Short name:
TLBP
Testis-type fatty acid-binding protein
Short name:
T-FABP
Gene namesi
Name:Fabp9
Synonyms:Perf15
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi620285. Fabp9.

Subcellular locationi

GO - Cellular componenti

  • acrosomal vesicle Source: RGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 132132Fatty acid-binding protein 9PRO_0000067386Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei13 – 131PhosphoserineCombined sources
Modified residuei14 – 141PhosphoserineCombined sources
Modified residuei40 – 401PhosphoserineCombined sources
Modified residuei42 – 421PhosphoserineCombined sources
Modified residuei44 – 441PhosphoserineCombined sources
Modified residuei91 – 911PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP55054.
PRIDEiP55054.

PTM databases

iPTMnetiP55054.

Expressioni

Tissue specificityi

Testis.

Gene expression databases

GenevisibleiP55054. RN.

Interactioni

Protein-protein interaction databases

BioGridi249200. 1 interaction.
STRINGi10116.ENSRNOP00000014949.

Structurei

3D structure databases

ProteinModelPortaliP55054.
SMRiP55054. Positions 5-132.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00760000118898.
HOGENOMiHOG000004829.
HOVERGENiHBG005633.
InParanoidiP55054.
OMAiMNNIVST.
OrthoDBiEOG7NW6BZ.
PhylomeDBiP55054.
TreeFamiTF316894.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000463. Fatty_acid-bd.
IPR031259. iLBP.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.
PROSITEiPS00214. FABP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P55054-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEPFLGTWK LVSSENFENY VRELGVECEP RKVACLIKPS VSISFNGERM
60 70 80 90 100
DIQAGSACRN TEISFKLGEE FEETTADNRK VKSLITFEGG SMIQIQRWLG
110 120 130
KQTTIKRRIV DGRMVVECTM NNVVSTRTYE RV
Length:132
Mass (Da):15,089
Last modified:October 1, 1996 - v1
Checksum:i032AB47D14D07549
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti3 – 31E → Q in AAH78817 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U07870 mRNA. Translation: AAA68627.1.
U09022 mRNA. Translation: AAA67873.1.
U66878 Genomic DNA. Translation: AAB07538.1.
BC078817 mRNA. Translation: AAH78817.1.
PIRiI52524.
RefSeqiNP_074045.1. NM_022854.1.
UniGeneiRn.10078.

Genome annotation databases

EnsembliENSRNOT00000014949; ENSRNOP00000014949; ENSRNOG00000011082.
GeneIDi64822.
KEGGirno:64822.
UCSCiRGD:620285. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U07870 mRNA. Translation: AAA68627.1.
U09022 mRNA. Translation: AAA67873.1.
U66878 Genomic DNA. Translation: AAB07538.1.
BC078817 mRNA. Translation: AAH78817.1.
PIRiI52524.
RefSeqiNP_074045.1. NM_022854.1.
UniGeneiRn.10078.

3D structure databases

ProteinModelPortaliP55054.
SMRiP55054. Positions 5-132.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi249200. 1 interaction.
STRINGi10116.ENSRNOP00000014949.

PTM databases

iPTMnetiP55054.

Proteomic databases

PaxDbiP55054.
PRIDEiP55054.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000014949; ENSRNOP00000014949; ENSRNOG00000011082.
GeneIDi64822.
KEGGirno:64822.
UCSCiRGD:620285. rat.

Organism-specific databases

CTDi646480.
RGDi620285. Fabp9.

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00760000118898.
HOGENOMiHOG000004829.
HOVERGENiHBG005633.
InParanoidiP55054.
OMAiMNNIVST.
OrthoDBiEOG7NW6BZ.
PhylomeDBiP55054.
TreeFamiTF316894.

Enzyme and pathway databases

ReactomeiR-RNO-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.

Miscellaneous databases

PROiP55054.

Gene expression databases

GenevisibleiP55054. RN.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000463. Fatty_acid-bd.
IPR031259. iLBP.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.
PROSITEiPS00214. FABP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A novel, testis-specific member of the cellular lipophilic transport protein superfamily, deduced from a complimentary deoxyribonucleic acid clone."
    Schmitt M.C., Jamison R.S., Orgebin-Crist M.C., Ong D.E.
    Biol. Reprod. 51:239-245(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: Sprague-Dawley.
    Tissue: Testis.
  2. "A novel testicular protein, with sequence similarities to a family of lipid binding proteins, is a major component of the rat sperm perinuclear theca."
    Oko R., Morales C.R.
    Dev. Biol. 166:235-245(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Testis.
  3. "Molecular cloning and structural analysis of the gene encoding PERF 15 protein present in the perinuclear theca of the rat spermatozoa."
    Pouresmaeili F., Morales C.R., Oko R.
    Biol. Reprod. 57:655-659(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Sprague-Dawley.
    Tissue: Testis.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  5. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-13; SER-14; SER-40; SER-42; SER-44 AND SER-91, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiFABP9_RAT
AccessioniPrimary (citable) accession number: P55054
Secondary accession number(s): Q68G09
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 8, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.