Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P55037

- GLTB_SYNY3

UniProt

P55037 - GLTB_SYNY3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ferredoxin-dependent glutamate synthase 1

Gene

gltB

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.

Cofactori

Protein has several cofactor binding sites:

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei43 – 431For GATase activityBy similarity
Metal bindingi1150 – 11501Iron-sulfur (3Fe-4S)By similarity
Metal bindingi1156 – 11561Iron-sulfur (3Fe-4S)By similarity
Metal bindingi1161 – 11611Iron-sulfur (3Fe-4S)By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi1097 – 115458FMNBy similarityAdd
BLAST

GO - Molecular functioni

  1. 3 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  2. glutamate synthase (ferredoxin) activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. glutamine metabolic process Source: UniProtKB-KW
  2. L-glutamate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Amino-acid biosynthesis, Glutamate biosynthesis

Keywords - Ligandi

3Fe-4S, FAD, Flavoprotein, FMN, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00045.
UPA00634; UER00691.

Protein family/group databases

MEROPSiC44.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Ferredoxin-dependent glutamate synthase 1 (EC:1.4.7.1)
Alternative name(s):
Fd-GOGAT
Gene namesi
Name:gltB
Ordered Locus Names:sll1502
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 15501550Ferredoxin-dependent glutamate synthase 1PRO_0000170793Add
BLAST

Proteomic databases

PaxDbiP55037.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
trxAP522312EBI-862093,EBI-862916

Protein-protein interaction databases

IntActiP55037. 3 interactions.
STRINGi1148.sll1502.

Structurei

3D structure databases

ProteinModelPortaliP55037.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini43 – 440398Glutamine amidotransferase type-2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glutamate synthase family.Curated
Contains 1 glutamine amidotransferase type-2 domain.PROSITE-ProRule annotation

Keywords - Domaini

Glutamine amidotransferase

Phylogenomic databases

eggNOGiCOG0069.
HOGENOMiHOG000031559.
InParanoidiP55037.
KOiK00284.
OMAiRRYGHAG.
OrthoDBiEOG60W7PX.
PhylomeDBiP55037.

Family and domain databases

Gene3Di2.160.20.60. 1 hit.
3.20.20.70. 2 hits.
3.60.20.10. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR002489. Glu_synth_asu_C.
IPR006982. Glu_synth_centr_N.
IPR002932. Glu_synthdom.
IPR029055. Ntn_hydrolases_N.
[Graphical view]
PfamiPF00310. GATase_2. 1 hit.
PF04898. Glu_syn_central. 1 hit.
PF01645. Glu_synthase. 1 hit.
PF01493. GXGXG. 1 hit.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
SSF69336. SSF69336. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P55037-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPCHEGLHPL VPNFCTVTSP MNSSHLAPQV QGLYDPQNEH DACGVGFIVQ
60 70 80 90 100
MKGKVSHDIV EQGLQMLVNL EHRGACGCEP NTGDGAGILI QVPHKFIQKI
110 120 130 140 150
AGAEGITIPA PGQYAVGNIY GSPDPLARAE ARQKFNDIVA QEGLKVLGWR
160 170 180 190 200
DIPTQNEPLG ETAIASEPFM QQVYIARPEG LTDDLDFERK LYVIRKLTHG
210 220 230 240 250
AIRSPKIDTY WYVASLSART LVYKGMLTTA QVGQYYPELH DPDMESALAL
260 270 280 290 300
VHSRFSTNTF PSWERSHPYR YIAHNGEINT MRGNVNWMQA RQALFESSLF
310 320 330 340 350
GEDMAKVQPV INIDGSDSTI FDNALELLYL AGRSLPHAVM MMIPEPWSAH
360 370 380 390 400
ESMSQEKKAF YKYHSCLMEP WDGPASIAFT NGKMMGAVLD RNGLRPSRYY
410 420 430 440 450
VTKDDLVIMA SEAGVLPIEP ERVAKKGRLQ PGRMFLVDME QGRIIADEEI
460 470 480 490 500
KQEIVSQHPY GEWLAANLKS LEQLPSPGNV PGTDAESLRQ RQMAFGYTFE
510 520 530 540 550
ELRILLAPMG RDGVEAIGSM GADTPLAVLS DKPKLLYNYF QQLFAQVTNP
560 570 580 590 600
PIDSIREEII TSAETTIGGE GNLLDPRPES CRLIELKTPI LTNEDLAKLK
610 620 630 640 650
ALDDDEFKSV TLDILFDPNQ GEAGLKTALD NLFTEADQAI SQGANLIILS
660 670 680 690 700
DRQVSAEKAA IPALLAVSGL HHHLIRNGSR TKVGLVLESG EPREVHHFAV
710 720 730 740 750
LLGYGCGAIN PYLAFETLDG MIAEGLLVNV DHKTACKNYI KAATKGVIKV
760 770 780 790 800
ASKIGISTIQ SYRGAQIFEA VGLNQSVIDE YFCRTSSRIQ GSDLGVIAQE
810 820 830 840 850
AILRHQHAFA PRPGDLHTLD VGGEYQWRKD GEEHLFSPQT IHLLQRAVRE
860 870 880 890 900
GNYELYKQYA ALVNEQNQKF FTLRGLLDFQ DRESIPLEEV EPIEAIMKRF
910 920 930 940 950
KTGAMSYGSI SKEAHESLAI AMNRIGGKSN TGEGGEDPER FTWTNDQGDS
960 970 980 990 1000
KNSAIKQVAS GRFGVTSLYL SQAKEIQIKM AQGAKPGEGG QLPGKKVYPW
1010 1020 1030 1040 1050
IAKVRHSTPG VGLISPPPHH DIYSIEDLAE LIHDLKNANR EARINVKLVS
1060 1070 1080 1090 1100
EVGVGTIAAG VAKAHADVVL VSGYDGGTGA SPQTSIKHAG LPWELGLAET
1110 1120 1130 1140 1150
HQTLVLNNLR SRIVVETDGQ MKTGRDVAIA ALLGAEEFGF STAPLVSLGC
1160 1170 1180 1190 1200
IMMRACHLNT CPVGIATQNP ELRAKFTGDP AHAVNFMTFI ATELREVMAQ
1210 1220 1230 1240 1250
LGFRTINEMV GRTDILEPKK AVAHWKAKGI DLSTILHQPE VGDDVGRYCQ
1260 1270 1280 1290 1300
IPQDHGLQHS LDITQLLDLC QPAIAKGEKV TATLPITNIN RVVGTIVGNE
1310 1320 1330 1340 1350
ITKRHWEGLP EDTVHLHFQG SAGQSFGAFI PKGMTLELEG DANDYLGKGL
1360 1370 1380 1390 1400
SGGKIIVYPP KGSSFIASEN IIAGNVCLYG ATAGEVYISG MVGERFCVRN
1410 1420 1430 1440 1450
SGVNTVVEAV GDHGCEYMTG GKVVVLGQTG RNFAAGMSGG VAYIFDETGD
1460 1470 1480 1490 1500
FATRCNSAMV GLEKLEDPEE IKDLKELIQN HVNYTDSAKG KAVLADWEAS
1510 1520 1530 1540 1550
IPKFVKVMPR DYKRVLQAIK KALEAGLSGD DALNAAFEEN AKDVARIGGS
Length:1,550
Mass (Da):169,071
Last modified:October 1, 1996 - v1
Checksum:i07AA64D832296943
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X80485 Genomic DNA. Translation: CAA56652.1.
BA000022 Genomic DNA. Translation: BAA17018.1.
PIRiS60228.
RefSeqiNP_440338.1. NC_000911.1.
YP_005650395.1. NC_017277.1.
YP_007450221.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17018; BAA17018; BAA17018.
GeneIDi953637.
KEGGisyn:sll1502.
PATRICi23837822. VBISynSp132158_0480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X80485 Genomic DNA. Translation: CAA56652.1 .
BA000022 Genomic DNA. Translation: BAA17018.1 .
PIRi S60228.
RefSeqi NP_440338.1. NC_000911.1.
YP_005650395.1. NC_017277.1.
YP_007450221.1. NC_020286.1.

3D structure databases

ProteinModelPortali P55037.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P55037. 3 interactions.
STRINGi 1148.sll1502.

Protein family/group databases

MEROPSi C44.003.

Proteomic databases

PaxDbi P55037.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA17018 ; BAA17018 ; BAA17018 .
GeneIDi 953637.
KEGGi syn:sll1502.
PATRICi 23837822. VBISynSp132158_0480.

Phylogenomic databases

eggNOGi COG0069.
HOGENOMi HOG000031559.
InParanoidi P55037.
KOi K00284.
OMAi RRYGHAG.
OrthoDBi EOG60W7PX.
PhylomeDBi P55037.

Enzyme and pathway databases

UniPathwayi UPA00045 .
UPA00634 ; UER00691 .

Family and domain databases

Gene3Di 2.160.20.60. 1 hit.
3.20.20.70. 2 hits.
3.60.20.10. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR002489. Glu_synth_asu_C.
IPR006982. Glu_synth_centr_N.
IPR002932. Glu_synthdom.
IPR029055. Ntn_hydrolases_N.
[Graphical view ]
Pfami PF00310. GATase_2. 1 hit.
PF04898. Glu_syn_central. 1 hit.
PF01645. Glu_synthase. 1 hit.
PF01493. GXGXG. 1 hit.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
SSF69336. SSF69336. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Existence of two ferredoxin-glutamate synthases in the cyanobacterium Synechocystis sp. PCC 6803. Isolation and insertional inactivation of gltB and gltS genes."
    Navarro F., Chavez S., Candau P., Florencio F.J.
    Plant Mol. Biol. 27:753-767(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiGLTB_SYNY3
AccessioniPrimary (citable) accession number: P55037
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 26, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

It is uncertain whether Met-1 or Met-21 is the initiator.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3