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P54969 (ILL1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 115. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
IAA-amino acid hydrolase ILR1-like 1

EC=3.5.1.-
Gene names
Name:ILL1
Ordered Locus Names:At5g56650
ORF Names:MIK19.10
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length438 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA), including IAA-Ala, IAA-Asn and IAA-Tyr.

Cofactor

Manganese. The ion enhances activity.

Subcellular location

Endoplasmic reticulum lumen Potential.

Sequence similarities

Belongs to the peptidase M20 family.

Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
   DomainSignal
   LigandManganese
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentGolgi apparatus

Inferred from direct assay PubMed 22430844. Source: TAIR

endoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionhydrolase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 438418IAA-amino acid hydrolase ILR1-like 1
PRO_0000001189

Regions

Motif435 – 4384Prevents secretion from ER Potential

Sequences

Sequence LengthMass (Da)Tools
P54969 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 8EAB21F1E62370B1

FASTA43847,692
        10         20         30         40         50         60 
MALNNFLTFQ LLLLLLRVSS ESPWIVAGDV SRIPINFLEL AKSPEVFDSM VRIRRKIHEN 

        70         80         90        100        110        120 
PELGYEEFET SKFIRSELDL IGVKYRFPVA ITGIIGYIGT GEPPFVALRA DMDALPIQEA 

       130        140        150        160        170        180 
VEWEHKSKNP GKMHACGHDG HVAMLLGAAK ILQQHRQHLQ GTVVLIFQPA EEGLSGAKMM 

       190        200        210        220        230        240 
REEGALKNVE AIFGIHLSPR TPFGKAASLA GSFMAGAGAF EAVITGKGGH AAIPQHTIDP 

       250        260        270        280        290        300 
VVAASSIVLS LQHLVSRETD PSDSKVVTVT KVNGGNAFNV IPDSITIGGT LRAFTGFTQL 

       310        320        330        340        350        360 
QERIKEIITK QAAVHRCNAS VNLAPNGNQP MPPTVNNMDL YKKFKKVVRD LLGQEAFVEA 

       370        380        390        400        410        420 
VPEMGSEDFS YFAETIPGHF SLLGMQDETQ GYASSHSPHY RINEDVLPYG AAIHATMAVQ 

       430 
YLKDKASKGS VSGFHDEL 

« Hide

References

« Hide 'large scale' references
[1]"ILR1, an amidohydrolase that releases active indole-3-acetic acid from conjugates."
Bartel B., Fink G.R.
Science 268:1745-1748(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Landsberg erecta.
[2]"IAR3 encodes an auxin conjugate hydrolase from Arabidopsis."
Davies R.T., Goetz D.H., Lasswell J.E., Anderson M.N., Bartel B.
Plant Cell 11:365-376(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Columbia.
[3]"Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
DNA Res. 5:203-216(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[4]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[5]"Characterization of a family of IAA-amino acid conjugate hydrolases from Arabidopsis."
LeClere S., Tellez R., Rampey R.A., Matsuda S.P.T., Bartel B.
J. Biol. Chem. 277:20446-20452(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U23795 mRNA. Translation: AAC49015.1.
AF047031 Genomic DNA. Translation: AAC04865.1.
AB013392 Genomic DNA. Translation: BAB09883.1.
CP002688 Genomic DNA. Translation: AED96792.1.
RefSeqNP_200476.1. NM_125048.1.
UniGeneAt.24009.

3D structure databases

ProteinModelPortalP54969.
SMRP54969. Positions 37-427.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid21010. 1 interaction.
STRING3702.AT5G56650.1-P.

Protein family/group databases

MEROPSM20.A03.

Proteomic databases

PaxDbP54969.
PRIDEP54969.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G56650.1; AT5G56650.1; AT5G56650.
GeneID835766.
KEGGath:AT5G56650.

Organism-specific databases

GeneFarm1958. 187.
TAIRAT5G56650.

Phylogenomic databases

eggNOGCOG1473.
HOGENOMHOG000241403.
InParanoidP54969.
KOK14664.
OMACEFEFVR.
PhylomeDBP54969.
ProtClustDBPLN02693.

Enzyme and pathway databases

BioCycARA:AT5G56650-MONOMER.

Gene expression databases

GenevestigatorP54969.

Family and domain databases

Gene3D3.30.70.360. 1 hit.
InterProIPR017439. Amidohydrolase.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
[Graphical view]
PfamPF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view]
PIRSFPIRSF005962. Pept_M20D_amidohydro. 1 hit.
SUPFAMSSF55031. SSF55031. 1 hit.
TIGRFAMsTIGR01891. amidohydrolases. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameILL1_ARATH
AccessionPrimary (citable) accession number: P54969
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 19, 2014
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names