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Protein

IAA-amino acid hydrolase ILR1-like 1

Gene

ILL1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA), including IAA-Ala, IAA-Asn and IAA-Tyr.1 Publication

Cofactori

Mn2+1 PublicationNote: The Mn2+ ion enhances activity.1 Publication

pH dependencei

Optimum pH is 7.5.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi136Manganese 1By similarity1
Metal bindingi136Manganese 2By similarity1
Metal bindingi138Manganese 2By similarity1
Metal bindingi172Manganese 1By similarity1
Metal bindingi196Manganese 2By similarity1
Metal bindingi396Manganese 1By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT5G56650-MONOMER

Protein family/group databases

MEROPSiM20.A03

Names & Taxonomyi

Protein namesi
Recommended name:
IAA-amino acid hydrolase ILR1-like 11 Publication (EC:3.5.1.-Curated)
Gene namesi
Name:ILL11 Publication
Ordered Locus Names:At5g56650Imported
ORF Names:MIK19.10Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G56650
TAIRilocus:2165076 AT5G56650

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000000118921 – 438IAA-amino acid hydrolase ILR1-like 1Add BLAST418

Proteomic databases

PaxDbiP54969
PRIDEiP54969

PTM databases

iPTMnetiP54969

Expressioni

Tissue specificityi

Expressed in leaves, stems, roots, siliques and flowers. Detected in pollen.1 Publication

Gene expression databases

ExpressionAtlasiP54969 baseline and differential
GenevisibleiP54969 AT

Interactioni

Protein-protein interaction databases

BioGridi21010, 1 interactor
STRINGi3702.AT5G56650.1

Structurei

3D structure databases

ProteinModelPortaliP54969
SMRiP54969
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi435 – 438Prevents secretion from ERPROSITE-ProRule annotation4

Sequence similaritiesi

Belongs to the peptidase M20 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IIRP Eukaryota
COG1473 LUCA
HOGENOMiHOG000241403
InParanoidiP54969
KOiK14664
OMAiKQTHAGR
OrthoDBiEOG09360A3R
PhylomeDBiP54969

Family and domain databases

InterProiView protein in InterPro
IPR017439 Amidohydrolase
IPR036264 Bact_exopeptidase_dim_dom
IPR002933 Peptidase_M20
IPR011650 Peptidase_M20_dimer
PfamiView protein in Pfam
PF07687 M20_dimer, 1 hit
PF01546 Peptidase_M20, 1 hit
PIRSFiPIRSF005962 Pept_M20D_amidohydro, 1 hit
SUPFAMiSSF55031 SSF55031, 1 hit
TIGRFAMsiTIGR01891 amidohydrolases, 1 hit
PROSITEiView protein in PROSITE
PS00014 ER_TARGET, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P54969-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALNNFLTFQ LLLLLLRVSS ESPWIVAGDV SRIPINFLEL AKSPEVFDSM
60 70 80 90 100
VRIRRKIHEN PELGYEEFET SKFIRSELDL IGVKYRFPVA ITGIIGYIGT
110 120 130 140 150
GEPPFVALRA DMDALPIQEA VEWEHKSKNP GKMHACGHDG HVAMLLGAAK
160 170 180 190 200
ILQQHRQHLQ GTVVLIFQPA EEGLSGAKMM REEGALKNVE AIFGIHLSPR
210 220 230 240 250
TPFGKAASLA GSFMAGAGAF EAVITGKGGH AAIPQHTIDP VVAASSIVLS
260 270 280 290 300
LQHLVSRETD PSDSKVVTVT KVNGGNAFNV IPDSITIGGT LRAFTGFTQL
310 320 330 340 350
QERIKEIITK QAAVHRCNAS VNLAPNGNQP MPPTVNNMDL YKKFKKVVRD
360 370 380 390 400
LLGQEAFVEA VPEMGSEDFS YFAETIPGHF SLLGMQDETQ GYASSHSPHY
410 420 430
RINEDVLPYG AAIHATMAVQ YLKDKASKGS VSGFHDEL
Length:438
Mass (Da):47,692
Last modified:October 1, 1996 - v1
Checksum:i8EAB21F1E62370B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U23795 mRNA Translation: AAC49015.1
AF047031 Genomic DNA Translation: AAC04865.1
AB013392 Genomic DNA Translation: BAB09883.1
CP002688 Genomic DNA Translation: AED96792.1
RefSeqiNP_200476.1, NM_125048.2
UniGeneiAt.24009

Genome annotation databases

EnsemblPlantsiAT5G56650.1; AT5G56650.1; AT5G56650
GeneIDi835766
GrameneiAT5G56650.1; AT5G56650.1; AT5G56650
KEGGiath:AT5G56650

Similar proteinsi

Entry informationi

Entry nameiILL1_ARATH
AccessioniPrimary (citable) accession number: P54969
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health