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Protein

IAA-amino acid hydrolase ILR1-like 1

Gene

ILL1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA), including IAA-Ala, IAA-Asn and IAA-Tyr.

Cofactori

Mn2+Note: The Mn2+ ion enhances activity.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciARA:AT5G56650-MONOMER.

Protein family/group databases

MEROPSiM20.A03.

Names & Taxonomyi

Protein namesi
Recommended name:
IAA-amino acid hydrolase ILR1-like 1 (EC:3.5.1.-)
Gene namesi
Name:ILL1
Ordered Locus Names:At5g56650
ORF Names:MIK19.10
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G56650.

Subcellular locationi

  • Endoplasmic reticulum lumen PROSITE-ProRule annotation

GO - Cellular componenti

  • endoplasmic reticulum lumen Source: UniProtKB-SubCell
  • Golgi apparatus Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000000118921 – 438IAA-amino acid hydrolase ILR1-like 1Add BLAST418

Proteomic databases

PaxDbiP54969.

PTM databases

iPTMnetiP54969.

Expressioni

Gene expression databases

ExpressionAtlasiP54969. baseline and differential.
GenevisibleiP54969. AT.

Interactioni

Protein-protein interaction databases

BioGridi21010. 1 interactor.
STRINGi3702.AT5G56650.1.

Structurei

3D structure databases

ProteinModelPortaliP54969.
SMRiP54969.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi435 – 438Prevents secretion from ERPROSITE-ProRule annotation4

Sequence similaritiesi

Belongs to the peptidase M20 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IIRP. Eukaryota.
COG1473. LUCA.
HOGENOMiHOG000241403.
InParanoidiP54969.
KOiK14664.
OMAiRRNLHEH.
OrthoDBiEOG09360A3R.
PhylomeDBiP54969.

Family and domain databases

Gene3Di3.30.70.360. 1 hit.
InterProiIPR017439. Amidohydrolase.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
[Graphical view]
PfamiPF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view]
PIRSFiPIRSF005962. Pept_M20D_amidohydro. 1 hit.
SUPFAMiSSF55031. SSF55031. 1 hit.
TIGRFAMsiTIGR01891. amidohydrolases. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P54969-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALNNFLTFQ LLLLLLRVSS ESPWIVAGDV SRIPINFLEL AKSPEVFDSM
60 70 80 90 100
VRIRRKIHEN PELGYEEFET SKFIRSELDL IGVKYRFPVA ITGIIGYIGT
110 120 130 140 150
GEPPFVALRA DMDALPIQEA VEWEHKSKNP GKMHACGHDG HVAMLLGAAK
160 170 180 190 200
ILQQHRQHLQ GTVVLIFQPA EEGLSGAKMM REEGALKNVE AIFGIHLSPR
210 220 230 240 250
TPFGKAASLA GSFMAGAGAF EAVITGKGGH AAIPQHTIDP VVAASSIVLS
260 270 280 290 300
LQHLVSRETD PSDSKVVTVT KVNGGNAFNV IPDSITIGGT LRAFTGFTQL
310 320 330 340 350
QERIKEIITK QAAVHRCNAS VNLAPNGNQP MPPTVNNMDL YKKFKKVVRD
360 370 380 390 400
LLGQEAFVEA VPEMGSEDFS YFAETIPGHF SLLGMQDETQ GYASSHSPHY
410 420 430
RINEDVLPYG AAIHATMAVQ YLKDKASKGS VSGFHDEL
Length:438
Mass (Da):47,692
Last modified:October 1, 1996 - v1
Checksum:i8EAB21F1E62370B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U23795 mRNA. Translation: AAC49015.1.
AF047031 Genomic DNA. Translation: AAC04865.1.
AB013392 Genomic DNA. Translation: BAB09883.1.
CP002688 Genomic DNA. Translation: AED96792.1.
RefSeqiNP_200476.1. NM_125048.2.
UniGeneiAt.24009.

Genome annotation databases

EnsemblPlantsiAT5G56650.1; AT5G56650.1; AT5G56650.
GeneIDi835766.
GrameneiAT5G56650.1; AT5G56650.1; AT5G56650.
KEGGiath:AT5G56650.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U23795 mRNA. Translation: AAC49015.1.
AF047031 Genomic DNA. Translation: AAC04865.1.
AB013392 Genomic DNA. Translation: BAB09883.1.
CP002688 Genomic DNA. Translation: AED96792.1.
RefSeqiNP_200476.1. NM_125048.2.
UniGeneiAt.24009.

3D structure databases

ProteinModelPortaliP54969.
SMRiP54969.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi21010. 1 interactor.
STRINGi3702.AT5G56650.1.

Protein family/group databases

MEROPSiM20.A03.

PTM databases

iPTMnetiP54969.

Proteomic databases

PaxDbiP54969.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G56650.1; AT5G56650.1; AT5G56650.
GeneIDi835766.
GrameneiAT5G56650.1; AT5G56650.1; AT5G56650.
KEGGiath:AT5G56650.

Organism-specific databases

TAIRiAT5G56650.

Phylogenomic databases

eggNOGiENOG410IIRP. Eukaryota.
COG1473. LUCA.
HOGENOMiHOG000241403.
InParanoidiP54969.
KOiK14664.
OMAiRRNLHEH.
OrthoDBiEOG09360A3R.
PhylomeDBiP54969.

Enzyme and pathway databases

BioCyciARA:AT5G56650-MONOMER.

Miscellaneous databases

PROiP54969.

Gene expression databases

ExpressionAtlasiP54969. baseline and differential.
GenevisibleiP54969. AT.

Family and domain databases

Gene3Di3.30.70.360. 1 hit.
InterProiIPR017439. Amidohydrolase.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
[Graphical view]
PfamiPF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view]
PIRSFiPIRSF005962. Pept_M20D_amidohydro. 1 hit.
SUPFAMiSSF55031. SSF55031. 1 hit.
TIGRFAMsiTIGR01891. amidohydrolases. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiILL1_ARATH
AccessioniPrimary (citable) accession number: P54969
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 30, 2016
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.