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Protein

Allergen Bla g 4

Gene
N/A
Organism
Blattella germanica (German cockroach) (Blatta germanica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Probable ligand-binding protein.

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Allergen Bla g 4
Alternative name(s):
Allergen Bla g IV
Allergen: Bla g 4
OrganismiBlattella germanica (German cockroach) (Blatta germanica)
Taxonomic identifieri6973 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraOrthopteroideaDictyopteraBlattodeaBlaberoideaEctobiidaeBlattellinaeBlattella

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei143. Bla g 4.
3141. Bla g 4.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei‹1 – 12Sequence analysisAdd BLAST›12
ChainiPRO_000001798413 – 182Allergen Bla g 4Add BLAST170

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi72N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

Secondary structure

1182
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni14 – 16Combined sources3
Helixi28 – 31Combined sources4
Beta strandi33 – 41Combined sources9
Helixi44 – 47Combined sources4
Beta strandi48 – 56Combined sources9
Turni57 – 59Combined sources3
Beta strandi60 – 66Combined sources7
Beta strandi74 – 83Combined sources10
Beta strandi86 – 91Combined sources6
Helixi96 – 98Combined sources3
Beta strandi100 – 107Combined sources8
Beta strandi109 – 117Combined sources9
Helixi120 – 122Combined sources3
Beta strandi126 – 133Combined sources8
Turni135 – 137Combined sources3
Helixi148 – 169Combined sources22
Helixi174 – 176Combined sources3
Beta strandi177 – 179Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3EBKX-ray1.90A/B7-182[»]
ProteinModelPortaliP54962.
SMRiP54962.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP54962.

Family & Domainsi

Sequence similaritiesi

Belongs to the calycin superfamily. Lipocalin family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR005657. Triabi/Procalin.
[Graphical view]
PfamiPF03973. Triabin. 1 hit.
[Graphical view]
SUPFAMiSSF50814. SSF50814. 1 hit.

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P54962-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AVLALCATDT LANEDCFRHE SLVPNLDYER FRGSWIIAAG TSEALTQYKC
60 70 80 90 100
WIDRFSYDDA LVSKYTDSQG KNRTTIRGRT KFEGNKFTID YNDKGKAFSA
110 120 130 140 150
PYSVLATDYE NYAIVEGCPA AANGHVIYVQ IRFSVRRFHP KLGDKEMIQH
160 170 180
YTLDQVNQHK KAIEEDLKHF NLKYEDLHST CH
Length:182
Mass (Da):20,927
Last modified:October 1, 1996 - v1
Checksum:i54B5C17485BEDF89
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U40767 mRNA. Translation: AAA87851.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U40767 mRNA. Translation: AAA87851.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3EBKX-ray1.90A/B7-182[»]
ProteinModelPortaliP54962.
SMRiP54962.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei143. Bla g 4.
3141. Bla g 4.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP54962.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR005657. Triabi/Procalin.
[Graphical view]
PfamiPF03973. Triabin. 1 hit.
[Graphical view]
SUPFAMiSSF50814. SSF50814. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiBLG4_BLAGE
AccessioniPrimary (citable) accession number: P54962
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.