Reviewed,
UniProtKB/Swiss-Prot P54904 (P5CR1_ARATH)
Last modified
November 25, 2008.
Version 68.
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Alternative products · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Pyrroline-5-carboxylate reductase Short name=P5C reductase Short name=P5CR EC=1.5.1.2 Alternative name(s): Protein EMBRYO DEFECTIVE 2772 | ||||||||
| Gene names |
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| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 276 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | L-proline + NAD(P)(+) = 1-pyrroline-5-carboxylate + NAD(P)H. |
| Pathway | |
| Subcellular location | |
| Sequence similarities | Belongs to the pyrroline-5-carboxylate reductase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Proline biosynthesis |
| Cellular component | Cytoplasm |
| Coding sequence diversity | Alternative splicing |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW proline biosynthetic processInferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | binding Inferred from electronic annotation. Source: InterPro pyrroline-5-carboxylate reductase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Alternative products
| This entry describes 1 isoform produced by alternative splicing. [Select] Notes: A number of isoforms are produced. According to EST sequences. | ||||||
| Isoform 1 (identifier: P54904-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 276 | 276 | Pyrroline-5-carboxylate reductase | PRO_0000187323 | |||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Osmoregulation of a pyrroline-5-carboxylate reductase gene in Arabidopsis thaliana." Verbruggen N., Villarroel R., van Montagu M. Plant Physiol. 103:771-781(1993) [PubMed: 8022935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | Verbruggen N., Villarroel R., Hua X., van Montagu M. Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: cv. Landsberg erecta. |
| [3] | "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana." Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. Fransz P.F.Nature 408:823-826(2000) [PubMed: 11130714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [4] | "Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. Ecker J.R.Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [5] | "Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
Cross-references
Sequence databases | |
|---|---|
| M76538 Genomic DNA. Translation: AAA61346.1. Y08951 Genomic DNA. Translation: CAA70148.1. AL391149 Genomic DNA. Translation: CAC01879.1. AF410303 mRNA. Translation: AAK95289.1. AY097368 mRNA. Translation: AAM19884.1. AY087530 mRNA. Translation: AAM65072.1. | |
| PIR | JQ2334. |
| RefSeq | NP_196984.1. |
| UniGene | At.385 |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 831332. |
| GenomeReviews | Gene locus AT5G14800 in contig BA000015_GR. |
| NMPDR | fig|3702.1.peg.23618. |
Organism-specific databases | |
| TAIR | At5g14800. |
Gene expression databases | |
| ArrayExpress | P54904. |
| GermOnline | AT5G14800. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR016040. NAD(P)-bd. IPR004455. NADP_OxRdtase_F420. IPR000304. P5CR. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| PANTHER | PTHR11645. P5CR. 1 hit. |
| Pfam | PF03807. F420_oxidored. 1 hit. [Graphical view] |
| PIRSF | PIRSF000193. Pyrrol-5-carb_rd. 1 hit. |
| TIGRFAMs | TIGR00112. proC. 1 hit. |
| PROSITE | PS00521. P5CR. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| LinkHub | P54904. |
Entry information
| Entry name | P5CR1_ARATH | ||||||||
| Accession | Primary (citable) accession number: P54904 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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