ID   CY552_PARDE             Reviewed;         176 AA.
AC   P54820;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   27-MAR-2024, entry version 112.
DE   RecName: Full=Cytochrome c-552;
DE   AltName: Full=Cytochrome c552;
GN   Name=cycM;
OS   Paracoccus denitrificans.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Paracoccus.
OX   NCBI_TaxID=266;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 66-76; 132-139
RP   AND 164-175.
RC   STRAIN=Pd 1235;
RX   PubMed=7628479; DOI=10.1111/j.1432-1033.1995.tb20695.x;
RA   Turba A., Jetzek M., Ludwig B.;
RT   "Purification of Paracoccus denitrificans cytochrome c552 and sequence
RT   analysis of the gene.";
RL   Eur. J. Biochem. 231:259-265(1995).
CC   -!- FUNCTION: Mediates the electron transport between the cytochrome bc1
CC       complex and cytochrome-c oxidase.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein.
CC   -!- PTM: Binds 1 heme c group covalently per subunit.
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DR   EMBL; X70367; CAA49830.1; -; Genomic_DNA.
DR   PIR; S65941; S31922.
DR   PDB; 1C7M; NMR; -; A=78-176.
DR   PDB; 1I6D; NMR; -; A=78-176.
DR   PDB; 1I6E; NMR; -; A=78-176.
DR   PDB; 1QL3; X-ray; 1.40 A; A/B/C/D=78-176.
DR   PDB; 1QL4; X-ray; 1.50 A; A/B/C/D=78-176.
DR   PDB; 3M97; X-ray; 1.33 A; X=38-176.
DR   PDBsum; 1C7M; -.
DR   PDBsum; 1I6D; -.
DR   PDBsum; 1I6E; -.
DR   PDBsum; 1QL3; -.
DR   PDBsum; 1QL4; -.
DR   PDBsum; 3M97; -.
DR   AlphaFoldDB; P54820; -.
DR   BMRB; P54820; -.
DR   SMR; P54820; -.
DR   DrugBank; DB03317; Ferroheme C.
DR   EvolutionaryTrace; P54820; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.760.10; Cytochrome c-like domain; 1.
DR   InterPro; IPR009056; Cyt_c-like_dom.
DR   InterPro; IPR036909; Cyt_c-like_dom_sf.
DR   InterPro; IPR002327; Cyt_c_1A/1B.
DR   PANTHER; PTHR11961; CYTOCHROME C; 1.
DR   PANTHER; PTHR11961:SF12; CYTOCHROME C; 1.
DR   Pfam; PF00034; Cytochrom_C; 1.
DR   PRINTS; PR00604; CYTCHRMECIAB.
DR   SUPFAM; SSF46626; Cytochrome c; 1.
DR   PROSITE; PS51007; CYTC; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell membrane; Direct protein sequencing; Electron transport;
KW   Heme; Iron; Membrane; Metal-binding; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..176
FT                   /note="Cytochrome c-552"
FT                   /id="PRO_0000108401"
FT   TRANSMEM        12..32
FT                   /note="Helical; Signal-anchor"
FT                   /evidence="ECO:0000255"
FT   BINDING         90
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /note="covalent"
FT   BINDING         93
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /note="covalent"
FT   BINDING         94
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         126
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   BINDING         154
FT                   /ligand="heme c"
FT                   /ligand_id="ChEBI:CHEBI:61717"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT   HELIX           71..76
FT                   /evidence="ECO:0007829|PDB:3M97"
FT   HELIX           80..86
FT                   /evidence="ECO:0007829|PDB:3M97"
FT   HELIX           87..89
FT                   /evidence="ECO:0007829|PDB:3M97"
FT   TURN            90..93
FT                   /evidence="ECO:0007829|PDB:3M97"
FT   STRAND          96..98
FT                   /evidence="ECO:0007829|PDB:3M97"
FT   STRAND          101..103
FT                   /evidence="ECO:0007829|PDB:3M97"
FT   HELIX           124..128
FT                   /evidence="ECO:0007829|PDB:3M97"
FT   HELIX           135..143
FT                   /evidence="ECO:0007829|PDB:3M97"
FT   HELIX           145..148
FT                   /evidence="ECO:0007829|PDB:3M97"
FT   HELIX           162..173
FT                   /evidence="ECO:0007829|PDB:3M97"
SQ   SEQUENCE   176 AA;  18209 MW;  99FE93503FBC2855 CRC64;
     MFDTMTVTKA AGALIGSLLF LLLMSWAASG IFHVGTSGHG AEGEEHAQAY TYPVESAGGA
     EGEAVDEGPD FATVLASADP AAGEKVFGKC KACHKLDGND GVGPHLNGVV GRTVAGVDGF
     NYSDPMKAHG GDWTPEALQE FLTNPKAVVK GTKMAFAGLP KIEDRANLIA YLEGQQ
//