P54820 (CY552_PARDE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c-552

Alternative name(s):
Cytochrome c552

Gene names

Name:

cycM

Organism

Paracoccus denitrificans

Taxonomic identifier

266 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus

Protein attributes

Sequence length	176 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Mediates the electron transport between the cytochrome bc1 complex and cytochrome-c oxidase.
Subcellular location	Cell membrane; Single-pass membrane protein.
Post-translational modification	Binds 1 heme group per subunit.

Ontologies

Keywords
Biological process	Electron transport Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	Heme Iron Metal-binding
Technical term	3D-structure Direct protein sequencing
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 176

176

Cytochrome c-552

PRO_0000108401

Regions

Transmembrane

12 – 32

21

Helical; Signal-anchor; Potential

Sites

Metal binding

94

1

Iron (heme axial ligand) By similarity

Metal binding

126

1

Iron (heme axial ligand) By similarity

Metal binding

154

1

Iron (heme axial ligand) By similarity

Binding site

90

1

Heme (covalent)

Binding site

93

1

Heme (covalent)

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

176

Helix Strand Turn

Details...

Helix

71 – 76

6

Helix

80 – 86

7

Helix

87 – 89

3

Turn

90 – 93

4

Beta strand

96 – 98

3

Beta strand

101 – 103

3

Helix

124 – 128

5

Helix

135 – 143

9

Helix

145 – 148

4

Helix

162 – 173

12

Sequences

	Sequence		Length	Mass (Da)
	P54820 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 99FE93503FBC2855	FASTA	176	18,209
	10 20 30 40 50 60 MFDTMTVTKA AGALIGSLLF LLLMSWAASG IFHVGTSGHG AEGEEHAQAY TYPVESAGGA 70 80 90 100 110 120 EGEAVDEGPD FATVLASADP AAGEKVFGKC KACHKLDGND GVGPHLNGVV GRTVAGVDGF 130 140 150 160 170 NYSDPMKAHG GDWTPEALQE FLTNPKAVVK GTKMAFAGLP KIEDRANLIA YLEGQQ

References

[1]	"Purification of Paracoccus denitrificans cytochrome c552 and sequence analysis of the gene." Turba A., Jetzek M., Ludwig B. Eur. J. Biochem. 231:259-265(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 66-76; 132-139 AND 164-175. Strain: Pd 1235.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

X70367 Genomic DNA. Translation: CAA49830.1.

PIR

S31922. S65941.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1C7M	NMR	-	A	78-176	[»]
1I6D	NMR	-	A	78-176	[»]
1I6E	NMR	-	A	78-176	[»]
1QL3	X-ray	1.40	A/B/C/D	78-176	[»]
1QL4	X-ray	1.50	A/B/C/D	78-176	[»]
1ZYY	model	-	C	78-176	[»]
3M97	X-ray	1.33	X	38-176	[»]

ProteinModelPortal

P54820.

SMR

P54820. Positions 78-176.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR002327. Cyt_c_1A/1B.
IPR009056. Cyt_c_dom.
IPR003088. Cyt_c_I.
[Graphical view]

PANTHER

PTHR11961. PTHR11961. 1 hit.

Pfam

PF00034. Cytochrom_C. 1 hit.
[Graphical view]

PRINTS

PR00604. CYTCHRMECIAB.

SUPFAM

SSF46626. Cytochrome_c. 1 hit.

PROSITE

PS51007. CYTC. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

P54820.

Entry information

Entry name

CY552_PARDE

Accession

Primary (citable) accession number: P54820

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	April 3, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program