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P54797 (TNG2_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transport and Golgi organization 2 homolog
Alternative name(s):
Ser/Thr-rich protein T10 in DGCR region
Gene names
Name:Tango2
Synonyms:D16H22S680E, T10
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Tissue specificity

Expressed in fetal liver, lung, heart and kidney. Ref.1

Developmental stage

In E13 embryos, expressed at high levels in the trachea, liver, esophagus, lung and velo-pharyngeal region. Also detected in the central nervous system. Ref.1

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentmitochondrion

Inferred from direct assay PubMed 18775783. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Transport and Golgi organization 2 homolog
PRO_0000072396

Sequences

Sequence LengthMass (Da)Tools
P54797 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 7A9DE9BDFFF882E3

FASTA27630,947
        10         20         30         40         50         60 
MCIIFFKFDP RPVSKNAYRL ILAANRDEFY NRPSKLADFW GNNSEILSGL DMEEGKAGGT 

        70         80         90        100        110        120 
WLGISTRGKL GALTNYLQPR QEPDARGRGE LVSHFLTSDM DSLSYLKKVS TEGHLYNGFN 

       130        140        150        160        170        180 
IIAADLSTSK GDVVCYYGNR GEPEPIVLTP GTYGLSNALL ETPWKKLCFG KQLFMEAVEQ 

       190        200        210        220        230        240 
SEALPKDVLV TQLLDVLNNE EAQLPDPAIE DQGQEYVQPI LNKYAAVWCR CASYGTRTNT 

       250        260        270 
IILVDANGHV TFTERSMLDK DTSRWETNTY EFTLQS 

« Hide

References

[1]"Isolation of a gene expressed during early embryogenesis from the region of 22q11 commonly deleted in DiGeorge syndrome."
Halford S., Wilson D.I., Daw S.C.M., Roberts C., Wadey R., Kamath S., Wickremasinghe A., Burn J., Goodship J., Mattei M.-G., Moormon A.F.M., Scambler P.J.
Hum. Mol. Genet. 2:1577-1582(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
Strain: BALB/c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X74504 mRNA. Translation: CAA52612.1.
CCDSCCDS28019.1.
PIRS37488. I48783.
UniGeneMm.265990.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP54797. 1 interaction.
MINTMINT-4136696.

PTM databases

PhosphoSiteP54797.

Proteomic databases

MaxQBP54797.
PaxDbP54797.
PRIDEP54797.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:101825. Tango2.

Phylogenomic databases

eggNOGCOG3332.
HOGENOMHOG000261311.
HOVERGENHBG017881.
InParanoidP54797.

Gene expression databases

CleanExMM_D16H22S680E.
GenevestigatorP54797.

Family and domain databases

InterProIPR008551. DUF833.
[Graphical view]
PANTHERPTHR17985. PTHR17985. 1 hit.
PfamPF05742. NRDE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP54797.
SOURCESearch...

Entry information

Entry nameTNG2_MOUSE
AccessionPrimary (citable) accession number: P54797
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: July 9, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot