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Protein

Transport and Golgi organization 2 homolog

Gene

Tango2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transport and Golgi organization 2 homolog
Alternative name(s):
Ser/Thr-rich protein T10 in DGCR region
Gene namesi
Name:Tango2
Synonyms:D16H22S680E, T10
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:101825. Tango2.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 276276Transport and Golgi organization 2 homologPRO_0000072396Add
BLAST

Proteomic databases

MaxQBiP54797.
PaxDbiP54797.
PRIDEiP54797.

PTM databases

PhosphoSiteiP54797.

Expressioni

Tissue specificityi

Expressed in fetal liver, lung, heart and kidney.1 Publication

Developmental stagei

In E13 embryos, expressed at high levels in the trachea, liver, esophagus, lung and velo-pharyngeal region. Also detected in the central nervous system.1 Publication

Gene expression databases

CleanExiMM_D16H22S680E.
GenevestigatoriP54797.

Interactioni

Protein-protein interaction databases

IntActiP54797. 1 interaction.
MINTiMINT-4136696.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG3332.
HOGENOMiHOG000261311.
HOVERGENiHBG017881.
InParanoidiP54797.

Family and domain databases

InterProiIPR008551. DUF833.
[Graphical view]
PANTHERiPTHR17985. PTHR17985. 1 hit.
PfamiPF05742. NRDE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P54797-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCIIFFKFDP RPVSKNAYRL ILAANRDEFY NRPSKLADFW GNNSEILSGL
60 70 80 90 100
DMEEGKAGGT WLGISTRGKL GALTNYLQPR QEPDARGRGE LVSHFLTSDM
110 120 130 140 150
DSLSYLKKVS TEGHLYNGFN IIAADLSTSK GDVVCYYGNR GEPEPIVLTP
160 170 180 190 200
GTYGLSNALL ETPWKKLCFG KQLFMEAVEQ SEALPKDVLV TQLLDVLNNE
210 220 230 240 250
EAQLPDPAIE DQGQEYVQPI LNKYAAVWCR CASYGTRTNT IILVDANGHV
260 270
TFTERSMLDK DTSRWETNTY EFTLQS
Length:276
Mass (Da):30,947
Last modified:October 1, 1996 - v1
Checksum:i7A9DE9BDFFF882E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74504 mRNA. Translation: CAA52612.1.
CCDSiCCDS28019.1.
PIRiI48783. S37488.
UniGeneiMm.265990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74504 mRNA. Translation: CAA52612.1.
CCDSiCCDS28019.1.
PIRiI48783. S37488.
UniGeneiMm.265990.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP54797. 1 interaction.
MINTiMINT-4136696.

PTM databases

PhosphoSiteiP54797.

Proteomic databases

MaxQBiP54797.
PaxDbiP54797.
PRIDEiP54797.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:101825. Tango2.

Phylogenomic databases

eggNOGiCOG3332.
HOGENOMiHOG000261311.
HOVERGENiHBG017881.
InParanoidiP54797.

Miscellaneous databases

PROiP54797.
SOURCEiSearch...

Gene expression databases

CleanExiMM_D16H22S680E.
GenevestigatoriP54797.

Family and domain databases

InterProiIPR008551. DUF833.
[Graphical view]
PANTHERiPTHR17985. PTHR17985. 1 hit.
PfamiPF05742. NRDE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Isolation of a gene expressed during early embryogenesis from the region of 22q11 commonly deleted in DiGeorge syndrome."
    Halford S., Wilson D.I., Daw S.C.M., Roberts C., Wadey R., Kamath S., Wickremasinghe A., Burn J., Goodship J., Mattei M.-G., Moormon A.F.M., Scambler P.J.
    Hum. Mol. Genet. 2:1577-1582(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
    Strain: BALB/c.

Entry informationi

Entry nameiTNG2_MOUSE
AccessioniPrimary (citable) accession number: P54797
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: January 7, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.