P54797 (TNG2_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transport and Golgi organization 2 homolog

Alternative name(s):
Ser/Thr-rich protein T10 in DGCR region

Gene names

Name:	Tango2
Synonyms:	D16H22S680E, T10

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Tissue specificity	Expressed in fetal liver, lung, heart and kidney. Ref.1
Developmental stage	In E13 embryos, expressed at high levels in the trachea, liver, esophagus, lung and velo-pharyngeal region. Also detected in the central nervous system. Ref.1

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	mitochondrion Inferred from direct assay PubMed 18775783. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	Transport and Golgi organization 2 homolog		PRO_0000072396

Sequences

	Sequence		Length	Mass (Da)
	P54797 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 7A9DE9BDFFF882E3	FASTA	276	30,947
	10 20 30 40 50 60 MCIIFFKFDP RPVSKNAYRL ILAANRDEFY NRPSKLADFW GNNSEILSGL DMEEGKAGGT 70 80 90 100 110 120 WLGISTRGKL GALTNYLQPR QEPDARGRGE LVSHFLTSDM DSLSYLKKVS TEGHLYNGFN 130 140 150 160 170 180 IIAADLSTSK GDVVCYYGNR GEPEPIVLTP GTYGLSNALL ETPWKKLCFG KQLFMEAVEQ 190 200 210 220 230 240 SEALPKDVLV TQLLDVLNNE EAQLPDPAIE DQGQEYVQPI LNKYAAVWCR CASYGTRTNT 250 260 270 IILVDANGHV TFTERSMLDK DTSRWETNTY EFTLQS

References

[1]

"Isolation of a gene expressed during early embryogenesis from the region of 22q11 commonly deleted in DiGeorge syndrome." Halford S., Wilson D.I., Daw S.C.M., Roberts C., Wadey R., Kamath S., Wickremasinghe A., Burn J., Goodship J., Mattei M.-G., Moormon A.F.M., Scambler P.J. Hum. Mol. Genet. 2:1577-1582(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, DEVELOPMENTAL STAGE. Strain: BALB/c.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X74504 mRNA. Translation: CAA52612.1.
IPI	IPI00108937.
PIR	S37488. I48783.
UniGene	Mm.265990.
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	P54797.
Proteomic databases
PaxDb	P54797.
PRIDE	P54797.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:101825. Tango2.
Phylogenomic databases
eggNOG	COG3332.
HOGENOM	HOG000261311.
HOVERGEN	HBG017881.
InParanoid	P54797.
OrthoDB	EOG45X7WW.
Gene expression databases
CleanEx	MM_D16H22S680E.
Genevestigator	P54797.
GermOnline	ENSMUSG00000013539. Mus musculus.
Family and domain databases
InterPro	IPR008551. DUF833. [Graphical view]
PANTHER	PTHR17985. PTHR17985. 1 hit.
Pfam	PF05742. NRDE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

TNG2_MOUSE

Accession

Primary (citable) accession number: P54797

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	April 3, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program