Reviewed, UniProtKB/Swiss-Prot P54757 (EPHA5_RAT)

Names and origin

Protein names

Recommended name:
    Ephrin type-A receptor 5
    EC=2.7.10.1
Alternative name(s):
    Tyrosine-protein kinase receptor EHK-1
    EPH homology kinase 1

Gene names

Name:	Epha5
Synonyms:	Ehk-1, Ekh1

Organism

Rattus norvegicus (Rat)

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	1005 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5.
Catalytic activity	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Subcellular location	Membrane; Single-pass type I membrane protein.
Tissue specificity	Almost exclusively expressed in the nervous system. Predominantly expressed in neurons.
Sequence similarities	Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain. Contains 1 SAM (sterile alpha motif) domain.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Alternative splicing
Domain	Repeat Signal Transmembrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Receptor Transferase Tyrosine-protein kinase
PTM	Glycoprotein Phosphoprotein
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro transmembrane receptor protein tyrosine kinase signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ephrin receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: P54757-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: P54757-2)

The sequence of this isoform differs from the canonical sequence as follows:
     306-357: VCRPGFFKASPHSQTCSKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACT → G

Isoform 3 (identifier: P54757-3)

The sequence of this isoform differs from the canonical sequence as follows:
     358-470: RPPSAPRNAI...SVNVTTNQAA → T

Note: Ref.2 (CAA55357) sequence differs from that shown due to several frameshifts.

Isoform 4 (identifier: P54757-4)

The sequence of this isoform differs from the canonical sequence as follows:
     358-470: RPPSAPRNAI...SVNVTTNQAA → T
     597-621: SGSCCECGCGRASSLCAVAHPSLIW → R

Isoform 5 (identifier: P54757-5)

The sequence of this isoform differs from the canonical sequence as follows:
     306-357: VCRPGFFKASPHSQTCSKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACT → G
     358-470: RPPSAPRNAI...SVNVTTNQAA → T
     597-621: SGSCCECGCGRASSLCAVAHPSLIW → R

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 26	26	By similarity
	Chain	27 – 1005	979	Ephrin type-A receptor 5		PRO_0000016814
Regions
	Topological domain	27 – 575	549	Extracellular Potential
	Transmembrane	576 – 596	21	Potential
	Topological domain	597 – 1005	409	Cytoplasmic Potential
	Domain	359 – 461	103	Fibronectin type-III 1
	Domain	471 – 561	91	Fibronectin type-III 2
	Domain	677 – 938	262	Protein kinase
	Domain	967 – 1005	39	SAM
	Nucleotide binding	683 – 691	9	ATP By similarity
	Compositional bias	222 – 356	135	Cys-rich
Sites
	Active site	802	1	Proton acceptor By similarity
	Binding site	709	1	ATP By similarity
Amino acid modifications
	Modified residue	652	1	Phosphotyrosine; by autocatalysis By similarity
	Modified residue	658	1	Phosphotyrosine; by autocatalysis By similarity
	Modified residue	835	1	Phosphotyrosine; by autocatalysis Potential
	Modified residue	984	1	Phosphotyrosine; by autocatalysis By similarity
	Glycosylation	266	1	N-linked (GlcNAc...) Potential
	Glycosylation	301	1	N-linked (GlcNAc...) Potential
	Glycosylation	371	1	N-linked (GlcNAc...) Potential
	Glycosylation	425	1	N-linked (GlcNAc...) Potential
	Glycosylation	438	1	N-linked (GlcNAc...) Potential
	Glycosylation	463	1	N-linked (GlcNAc...) Potential		VSP_003000
Natural variations
	Alternative sequence	306 – 357	52	VCRPG…TMACT → G in isoform 2 and isoform 5.		VSP_003001
	Alternative sequence	358 – 470	113	RPPSA…TNQAA → T in isoform 3, isoform 4 and isoform 5.		VSP_003002
	Alternative sequence	597 – 621	25	SGSCC…PSLIW → R in isoform 4 and isoform 5.		VSP_003003
Experimental info
	Sequence conflict	170	1	D → E in CAA55357. Ref.2
	Sequence conflict	566	1	G → A in CAA55357. Ref.2
	Sequence conflict	578	1	G → A in CAA55357. Ref.2
	Sequence conflict	669	1	G → A in CAA55357. Ref.2
	Sequence conflict	708	1	T → I in CAA55357. Ref.2
	Sequence conflict	979	1	T → I in CAA55357. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 1AED42C99693C574	FASTA	1,005	111,007
	10 20 30 40 50 60 MRGSGPRGAG RRRTQGRGGG GDTPRVPASL AGCYSAPLKG PLWTCLLLCA ALRTLLASPS 70 80 90 100 110 120 NEVNLLDSRT VLGDLGWIAF PKNGWEEIGE VDENYAPIHT YQVCKVMEQN QNNWLLTSWI 130 140 150 160 170 180 SNEGASRIFI ELKFTLRDCN SLPGGLGTCK ETFNMYYFES DDENGRNIKD NQYIKIDTIA 190 200 210 220 230 240 ADESFTELDL GDRVMKLNTE VRDVGPLSKK GFYLAFQDVG ACIALVSVRV YYKKCPSVVR 250 260 270 280 290 300 HLAVFPDTIT GADSSQLLEV SGSCVNHSVT DDPPKMHCSA EGEWLVPIGK CMCKAGYEEK 310 320 330 340 350 360 NGTCQVCRPG FFKASPHSQT CSKCPPHSYT HEEASTSCVC EKDYFRRESD PPTMACTRPP 370 380 390 400 410 420 SAPRNAISNV NETSVFLEWI PPADTGGGKD VSYYILCKKC NSHAGVCEEC GGHVRYLPQQ 430 440 450 460 470 480 IGLKNTSVMM ADPLAHTNYT FEIEAVNGVS DLSPGTRQYV SVNVTTNQAA PSPVTNVKKG 490 500 510 520 530 540 KIAKNSISLS WQEPDRPNGI ILEYEIKYFE KDQETSYTII KSKETTITAE GLKPASVYVF 550 560 570 580 590 600 QIRARTAAGY GVFSRRFEFE TTPVFGASND QSQIPIIGVS VTVGVILLAV MIGFLLSGSC 610 620 630 640 650 660 CECGCGRASS LCAVAHPSLI WRCGYSKAKQ DPEEEKMHFH NGHIKLPGVR TYIDPHTYED 670 680 690 700 710 720 PTQAVHEFGK EIEASCITIE RVIGAGEFGE VCSGRLKLPG KRELPVATKT LKVGYTEKQR 730 740 750 760 770 780 RDFLSEASIM GQFDHPNIIH LEGVVTKSKP VMIVTEYMEN GSLDTFLKKN DGQFTVIQLV 790 800 810 820 830 840 GMLRGIAAGM KYLSDMGYVH RDLAARNILI NSNLVCKVSD FGLSRVLEDD PEAAYTTRGG 850 860 870 880 890 900 KIPIRWTAPE AIAFRKFTSA SDVWSYGIVM WEVVSYGERP YWEMTNQDVI KAVEEGYRLP 910 920 930 940 950 960 SPMDCPAALY QLMLDCWQKD RNSRPKFDDI VNMLDKLIRN PSSLKTLVNA SSRVSTLLAE 970 980 990 1000 HGSLGSGAYR SVGEWLEATK MGRYTEIFME NGYSSMDAVA QVTLE
	Isoform 2. Checksum: A576627951A20FE0	FASTA	954	105,241
	10 20 30 40 50 60 MRGSGPRGAG RRRTQGRGGG GDTPRVPASL AGCYSAPLKG PLWTCLLLCA ALRTLLASPS 70 80 90 100 110 120 NEVNLLDSRT VLGDLGWIAF PKNGWEEIGE VDENYAPIHT YQVCKVMEQN QNNWLLTSWI 130 140 150 160 170 180 SNEGASRIFI ELKFTLRDCN SLPGGLGTCK ETFNMYYFES DDENGRNIKD NQYIKIDTIA 190 200 210 220 230 240 ADESFTELDL GDRVMKLNTE VRDVGPLSKK GFYLAFQDVG ACIALVSVRV YYKKCPSVVR 250 260 270 280 290 300 HLAVFPDTIT GADSSQLLEV SGSCVNHSVT DDPPKMHCSA EGEWLVPIGK CMCKAGYEEK 310 320 330 340 350 360 NGTCQGRPPS APRNAISNVN ETSVFLEWIP PADTGGGKDV SYYILCKKCN SHAGVCEECG 370 380 390 400 410 420 GHVRYLPQQI GLKNTSVMMA DPLAHTNYTF EIEAVNGVSD LSPGTRQYVS VNVTTNQAAP 430 440 450 460 470 480 SPVTNVKKGK IAKNSISLSW QEPDRPNGII LEYEIKYFEK DQETSYTIIK SKETTITAEG 490 500 510 520 530 540 LKPASVYVFQ IRARTAAGYG VFSRRFEFET TPVFGASNDQ SQIPIIGVSV TVGVILLAVM 550 560 570 580 590 600 IGFLLSGSCC ECGCGRASSL CAVAHPSLIW RCGYSKAKQD PEEEKMHFHN GHIKLPGVRT 610 620 630 640 650 660 YIDPHTYEDP TQAVHEFGKE IEASCITIER VIGAGEFGEV CSGRLKLPGK RELPVATKTL 670 680 690 700 710 720 KVGYTEKQRR DFLSEASIMG QFDHPNIIHL EGVVTKSKPV MIVTEYMENG SLDTFLKKND 730 740 750 760 770 780 GQFTVIQLVG MLRGIAAGMK YLSDMGYVHR DLAARNILIN SNLVCKVSDF GLSRVLEDDP 790 800 810 820 830 840 EAAYTTRGGK IPIRWTAPEA IAFRKFTSAS DVWSYGIVMW EVVSYGERPY WEMTNQDVIK 850 860 870 880 890 900 AVEEGYRLPS PMDCPAALYQ LMLDCWQKDR NSRPKFDDIV NMLDKLIRNP SSLKTLVNAS 910 920 930 940 950 SRVSTLLAEH GSLGSGAYRS VGEWLEATKM GRYTEIFMEN GYSSMDAVAQ VTLE
	Isoform 3. Checksum: CC3FC19A3DAD4F67	FASTA	893	98,956
	10 20 30 40 50 60 MRGSGPRGAG RRRTQGRGGG GDTPRVPASL AGCYSAPLKG PLWTCLLLCA ALRTLLASPS 70 80 90 100 110 120 NEVNLLDSRT VLGDLGWIAF PKNGWEEIGE VDENYAPIHT YQVCKVMEQN QNNWLLTSWI 130 140 150 160 170 180 SNEGASRIFI ELKFTLRDCN SLPGGLGTCK ETFNMYYFES DDENGRNIKD NQYIKIDTIA 190 200 210 220 230 240 ADESFTELDL GDRVMKLNTE VRDVGPLSKK GFYLAFQDVG ACIALVSVRV YYKKCPSVVR 250 260 270 280 290 300 HLAVFPDTIT GADSSQLLEV SGSCVNHSVT DDPPKMHCSA EGEWLVPIGK CMCKAGYEEK 310 320 330 340 350 360 NGTCQVCRPG FFKASPHSQT CSKCPPHSYT HEEASTSCVC EKDYFRRESD PPTMACTTPS 370 380 390 400 410 420 PVTNVKKGKI AKNSISLSWQ EPDRPNGIIL EYEIKYFEKD QETSYTIIKS KETTITAEGL 430 440 450 460 470 480 KPASVYVFQI RARTAAGYGV FSRRFEFETT PVFGASNDQS QIPIIGVSVT VGVILLAVMI 490 500 510 520 530 540 GFLLSGSCCE CGCGRASSLC AVAHPSLIWR CGYSKAKQDP EEEKMHFHNG HIKLPGVRTY 550 560 570 580 590 600 IDPHTYEDPT QAVHEFGKEI EASCITIERV IGAGEFGEVC SGRLKLPGKR ELPVATKTLK 610 620 630 640 650 660 VGYTEKQRRD FLSEASIMGQ FDHPNIIHLE GVVTKSKPVM IVTEYMENGS LDTFLKKNDG 670 680 690 700 710 720 QFTVIQLVGM LRGIAAGMKY LSDMGYVHRD LAARNILINS NLVCKVSDFG LSRVLEDDPE 730 740 750 760 770 780 AAYTTRGGKI PIRWTAPEAI AFRKFTSASD VWSYGIVMWE VVSYGERPYW EMTNQDVIKA 790 800 810 820 830 840 VEEGYRLPSP MDCPAALYQL MLDCWQKDRN SRPKFDDIVN MLDKLIRNPS SLKTLVNASS 850 860 870 880 890 RVSTLLAEHG SLGSGAYRSV GEWLEATKMG RYTEIFMENG YSSMDAVAQV TLE
	Isoform 4. Checksum: 02B991C14388F987	FASTA	869	96,632
	10 20 30 40 50 60 MRGSGPRGAG RRRTQGRGGG GDTPRVPASL AGCYSAPLKG PLWTCLLLCA ALRTLLASPS 70 80 90 100 110 120 NEVNLLDSRT VLGDLGWIAF PKNGWEEIGE VDENYAPIHT YQVCKVMEQN QNNWLLTSWI 130 140 150 160 170 180 SNEGASRIFI ELKFTLRDCN SLPGGLGTCK ETFNMYYFES DDENGRNIKD NQYIKIDTIA 190 200 210 220 230 240 ADESFTELDL GDRVMKLNTE VRDVGPLSKK GFYLAFQDVG ACIALVSVRV YYKKCPSVVR 250 260 270 280 290 300 HLAVFPDTIT GADSSQLLEV SGSCVNHSVT DDPPKMHCSA EGEWLVPIGK CMCKAGYEEK 310 320 330 340 350 360 NGTCQVCRPG FFKASPHSQT CSKCPPHSYT HEEASTSCVC EKDYFRRESD PPTMACTTPS 370 380 390 400 410 420 PVTNVKKGKI AKNSISLSWQ EPDRPNGIIL EYEIKYFEKD QETSYTIIKS KETTITAEGL 430 440 450 460 470 480 KPASVYVFQI RARTAAGYGV FSRRFEFETT PVFGASNDQS QIPIIGVSVT VGVILLAVMI 490 500 510 520 530 540 GFLLRRCGYS KAKQDPEEEK MHFHNGHIKL PGVRTYIDPH TYEDPTQAVH EFGKEIEASC 550 560 570 580 590 600 ITIERVIGAG EFGEVCSGRL KLPGKRELPV ATKTLKVGYT EKQRRDFLSE ASIMGQFDHP 610 620 630 640 650 660 NIIHLEGVVT KSKPVMIVTE YMENGSLDTF LKKNDGQFTV IQLVGMLRGI AAGMKYLSDM 670 680 690 700 710 720 GYVHRDLAAR NILINSNLVC KVSDFGLSRV LEDDPEAAYT TRGGKIPIRW TAPEAIAFRK 730 740 750 760 770 780 FTSASDVWSY GIVMWEVVSY GERPYWEMTN QDVIKAVEEG YRLPSPMDCP AALYQLMLDC 790 800 810 820 830 840 WQKDRNSRPK FDDIVNMLDK LIRNPSSLKT LVNASSRVST LLAEHGSLGS GAYRSVGEWL 850 860 EATKMGRYTE IFMENGYSSM DAVAQVTLE
	Isoform 5. Checksum: 78A72B1189C07F64	FASTA	818	90,866
	10 20 30 40 50 60 MRGSGPRGAG RRRTQGRGGG GDTPRVPASL AGCYSAPLKG PLWTCLLLCA ALRTLLASPS 70 80 90 100 110 120 NEVNLLDSRT VLGDLGWIAF PKNGWEEIGE VDENYAPIHT YQVCKVMEQN QNNWLLTSWI 130 140 150 160 170 180 SNEGASRIFI ELKFTLRDCN SLPGGLGTCK ETFNMYYFES DDENGRNIKD NQYIKIDTIA 190 200 210 220 230 240 ADESFTELDL GDRVMKLNTE VRDVGPLSKK GFYLAFQDVG ACIALVSVRV YYKKCPSVVR 250 260 270 280 290 300 HLAVFPDTIT GADSSQLLEV SGSCVNHSVT DDPPKMHCSA EGEWLVPIGK CMCKAGYEEK 310 320 330 340 350 360 NGTCQGTPSP VTNVKKGKIA KNSISLSWQE PDRPNGIILE YEIKYFEKDQ ETSYTIIKSK 370 380 390 400 410 420 ETTITAEGLK PASVYVFQIR ARTAAGYGVF SRRFEFETTP VFGASNDQSQ IPIIGVSVTV 430 440 450 460 470 480 GVILLAVMIG FLLRRCGYSK AKQDPEEEKM HFHNGHIKLP GVRTYIDPHT YEDPTQAVHE 490 500 510 520 530 540 FGKEIEASCI TIERVIGAGE FGEVCSGRLK LPGKRELPVA TKTLKVGYTE KQRRDFLSEA 550 560 570 580 590 600 SIMGQFDHPN IIHLEGVVTK SKPVMIVTEY MENGSLDTFL KKNDGQFTVI QLVGMLRGIA 610 620 630 640 650 660 AGMKYLSDMG YVHRDLAARN ILINSNLVCK VSDFGLSRVL EDDPEAAYTT RGGKIPIRWT 670 680 690 700 710 720 APEAIAFRKF TSASDVWSYG IVMWEVVSYG ERPYWEMTNQ DVIKAVEEGY RLPSPMDCPA 730 740 750 760 770 780 ALYQLMLDCW QKDRNSRPKF DDIVNMLDKL IRNPSSLKTL VNASSRVSTL LAEHGSLGSG 790 800 810 AYRSVGEWLE ATKMGRYTEI FMENGYSSMD AVAQVTLE

References

[1]	"Ehk-1 and Ehk-2: two novel members of the Eph receptor-like tyrosine kinase family with distinctive structures and neuronal expression." Maisonpierre P.C., Barrezueta N.X., Yancopoulos G.D. Oncogene 8:3277-3288(1993) [PubMed: 7504232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 4 AND 5). Strain: Sprague-Dawley. Tissue: Brain.
[2]	"Expression and developmental regulation of Ehk-1, a neuronal Elk-like receptor tyrosine kinase in brain." Taylor V., Miescher G.C., Pfarr S., Honegger P., Breitschopf H., Lassmann H., Steck A.J. Neuroscience 63:163-178(1994) [PubMed: 7898646] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3). Strain: Sprague-Dawley. Tissue: Brain.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X78689 mRNA. Translation: CAA55357.1. Frameshift.
IPI	IPI00188217. IPI00230957. IPI00230958. IPI00230959. IPI00230960.
PIR	PT0186. S47489. S49015. S51603. S51604.
UniGene	Rn.24569
3D structure databases
HSSP	HSSP built from PDB template 1JPA based on UniProtKB P54763.
SMR	P54757. Positions 657-951.
ModBase	Search...
Protein-protein interaction databases
STRING	P54757.
PTM databases
PhosphoSite	P54757.
Proteomic databases
PRIDE	P54757.
Genome annotation databases
Ensembl	ENSRNOT00000002793; ENSRNOP00000002793; ENSRNOG00000002024; Rattus norvegicus. [Genome view] ENSRNOT00000002798; ENSRNOP00000002798; ENSRNOG00000002024; Rattus norvegicus. [Genome view] ENSRNOT00000042149; ENSRNOP00000047823; ENSRNOG00000002024; Rattus norvegicus. [Genome view] ENSRNOT00000043938; ENSRNOP00000043926; ENSRNOG00000002024; Rattus norvegicus. [Genome view] ENSRNOT00000047290; ENSRNOP00000040977; ENSRNOG00000002024; Rattus norvegicus. [Genome view]
Organism-specific databases
RGD	620831. Epha5.
Phylogenomic databases
HOVERGEN	P54757.
Enzyme and pathway databases
BRENDA	2.7.10.1. 248.
Gene expression databases
ArrayExpress	P54757.
Genevestigator	P54757.
GermOnline	ENSRNOG00000002024. Rattus norvegicus.
Family and domain databases
InterPro	IPR015215. BmKX. IPR013032. EGF-like_reg_CS. IPR001090. Ephrin_rcpt_lig-bd. IPR008957. Fibronectin_typ-III-like_fold. IPR003961. FN_III. IPR003962. FnIII_subd. IPR000719. Prot_kinase_core. IPR017441. Protein_kinase_ATP_BS. IPR001660. SAM. IPR013761. SAM_type. IPR001245. Tyr_pkinase. IPR008266. Tyr_pkinase_AS. IPR016257. TyrPK_ephrin_receptor. IPR001426. YKase_receptorV_CS. [Graphical view]
Gene3D	G3DSA:2.60.40.30. FN_III-like. 2 hits. G3DSA:1.10.150.50. SAM_type. 1 hit.
Pfam	PF09132. BmKX. 1 hit. PF01404. Ephrin_lbd. 1 hit. PF00041. fn3. 2 hits. PF07714. Pkinase_Tyr. 1 hit. PF00536. SAM_1. 1 hit. [Graphical view]
PIRSF	PIRSF000666. TyrPK_ephrin_receptor. 1 hit.
PRINTS	PR00014. FNTYPEIII. PR00109. TYRKINASE.
ProDom	PD001495. Ephrin_receptor. 1 hit. PD000001. Prot_kinase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00615. EPH_lbd. 1 hit. SM00060. FN3. 2 hits. SM00219. TyrKc. 1 hit. [Graphical view]
PROSITE	PS01186. EGF_2. 1 hit. Uncertain. PS50853. FN3. 2 hits. PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. PS00790. RECEPTOR_TYR_KIN_V_1. 1 hit. PS00791. RECEPTOR_TYR_KIN_V_2. 1 hit. PS50105. SAM_DOMAIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EPHA5_RAT

Accession

Primary (citable) accession number: P54757

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	October 13, 2009
This is version 95 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)