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P54740 (PKAB_STRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PkaB

EC=2.7.11.1
Gene names
Name:pkaB
Ordered Locus Names:SCO2973
ORF Names:SCE50.01, SCE59.32c
OrganismStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [Reference proteome] [HAMAP]
Taxonomic identifier100226 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Post-translational modification

Autophosphorylated mainly at Thr.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 417417Serine/threonine-protein kinase PkaB
PRO_0000171233

Regions

Domain9 – 270262Protein kinase
Nucleotide binding15 – 239ATP By similarity

Sites

Active site1301Proton acceptor By similarity
Binding site361ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P54740 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 3D66720FF17D3DE4

FASTA41743,417
        10         20         30         40         50         60 
MARKIGSRYT AHQILGRGSA GTVWLGEGPD GPVAIKLLRE DLASDQELVS RFVQERTALL 

        70         80         90        100        110        120 
GLDHPHVVSV RDLVVDGNDL ALVMDLVRGT DLRTRLDRER RLAPEAAVAV VADVADGLAA 

       130        140        150        160        170        180 
AHAAGVVHRD VKPENVLLDM QGPLGPGGSH PALLTDFGVA KLIDTPRRTR ATKIIGTPDY 

       190        200        210        220        230        240 
LAPEIVEGLP PRAAVDIYAL ATVLYELLAG FTPFGGGHPG AVLRRHVTET VVPLPGIPDE 

       250        260        270        280        290        300 
LWQLLVQCLA KAPASRLRAS ELSARLRELL PMLAGMAPLD VDEPDAEQPE DAPDASAASP 

       310        320        330        340        350        360 
AAPVSTAEPV RRRGAVPLVP GAKPADSNRD THTSMRVPAP DELAGGARGT ARAPRASGAP 

       370        380        390        400        410 
RPGSARNRAA TRRRRIAVGA GAVALVAAIG VGTWLATGGD EDGGGPQDTR NSAPAAP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D86821 Genomic DNA. Translation: BAA13169.1.
AL939114 Genomic DNA. Translation: CAD55460.1.
PIRJC4071.
RefSeqNP_733588.1. NC_003888.3.

3D structure databases

ProteinModelPortalP54740.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING100226.SCO2973.

PTM databases

PhosSiteP0502123.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD55460; CAD55460; CAD55460.
GeneID1098406.
KEGGsco:SCO2973.
PATRIC23735672. VBIStrCoe124346_3031.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000053674.
KOK08884.
OMARRHVTET.
OrthoDBEOG6B35XT.
PhylomeDBP54740.
ProtClustDBCLSK392718.

Enzyme and pathway databases

BRENDA2.7.11.1. 5998.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKAB_STRCO
AccessionPrimary (citable) accession number: P54740
Secondary accession number(s): Q9L061, Q9L1S2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families