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Protein

Serine/threonine-protein kinase D

Gene

spkD

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei40ATPPROSITE-ProRule annotation1
Active sitei136Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi15 – 23ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase D (EC:2.7.11.1)
Gene namesi
Name:spkD
Ordered Locus Names:sll0776
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001712421 – 505Serine/threonine-protein kinase DAdd BLAST505

Proteomic databases

PRIDEiP54735.

Interactioni

Protein-protein interaction databases

IntActiP54735. 14 interactors.

Structurei

3D structure databases

ProteinModelPortaliP54735.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 271Protein kinasePROSITE-ProRule annotationAdd BLAST263
Domaini436 – 505SH3bPROSITE-ProRule annotationAdd BLAST70

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation
Contains 1 SH3b domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000054695.
InParanoidiP54735.
KOiK08884.
OMAiFLAKDTQ.
PhylomeDBiP54735.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR003646. SH3-like_bac-type.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF08239. SH3_3. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
SM00287. SH3b. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS51781. SH3B. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P54735-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVQVLDRYE IVKSLGSGGF GDTFLAKDTQ IPSQKLVVIK RLKPANANSN
60 70 80 90 100
TSTELIQKLF EKEASVLEDL GEHNSQIPKL YSYFSNDNEF YLVQEYIQGV
110 120 130 140 150
SLNEIAPISS EQAKTILSSL LTTLKYIHSK GIIHRDIKPE NIILRDSDHL
160 170 180 190 200
PVLIDFGAVK ETMGAVTLGS GSTVSSVVIG TRGFMAPEQS SGRSVFSTDL
210 220 230 240 250
YALGLTIIYT LTKKLPVEFS SDQQTGQLDW QSHVSKIDSV LAKVINKAIE
260 270 280 290 300
MEPSRRYSSA EAMYQALHSL ISSGAEPALP METVRVAPSN EFLVTRSSTK
310 320 330 340 350
TAETVVKPVG NSHNNYSNNN GKSKIATLLT VLIGIIVVTA GLGGGFIITQ
360 370 380 390 400
QIKEAEARAA QAEKEKQEAE QKRIEAEQKI AENEKRQREL EQKRVEEERQ
410 420 430 440 450
RLAAEAERAK QERQRLAAER QRVQVLANQA KAMASGASAT IGGIPGSKNI
460 470 480 490 500
RSGPGTDYGV ITQGYTGEGL DILDSSTDSS GHVWYKVYHY GSGSTGWIAS

QLVNF
Length:505
Mass (Da):55,213
Last modified:October 1, 1996 - v1
Checksum:iC4F12A1886C4D51C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046600 Genomic DNA. Translation: BAB17036.1.
BA000022 Genomic DNA. Translation: BAA10726.1.
PIRiS77034.

Genome annotation databases

EnsemblBacteriaiBAA10726; BAA10726; BAA10726.
KEGGisyn:sll0776.
PATRICi23843054. VBISynSp132158_3065.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046600 Genomic DNA. Translation: BAB17036.1.
BA000022 Genomic DNA. Translation: BAA10726.1.
PIRiS77034.

3D structure databases

ProteinModelPortaliP54735.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP54735. 14 interactors.

Proteomic databases

PRIDEiP54735.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA10726; BAA10726; BAA10726.
KEGGisyn:sll0776.
PATRICi23843054. VBISynSp132158_3065.

Phylogenomic databases

HOGENOMiHOG000054695.
InParanoidiP54735.
KOiK08884.
OMAiFLAKDTQ.
PhylomeDBiP54735.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR003646. SH3-like_bac-type.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF08239. SH3_3. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
SM00287. SH3b. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS51781. SH3B. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSPKD_SYNY3
AccessioniPrimary (citable) accession number: P54735
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.