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Protein

Serine/threonine-protein kinase D

Gene

spkD

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401ATPPROSITE-ProRule annotation
Active sitei136 – 1361Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 239ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase D (EC:2.7.11.1)
Gene namesi
Name:spkD
Ordered Locus Names:sll0776
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 505505Serine/threonine-protein kinase DPRO_0000171242Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiP54735. 14 interactions.

Structurei

3D structure databases

ProteinModelPortaliP54735.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 271263Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000054695.
InParanoidiP54735.
KOiK08884.
OMAiFNDKESE.
OrthoDBiEOG6BKJ4J.
PhylomeDBiP54735.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR003646. SH3-like_bac-type.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF08239. SH3_3. 1 hit.
[Graphical view]
SMARTiSM00287. SH3b. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P54735-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVQVLDRYE IVKSLGSGGF GDTFLAKDTQ IPSQKLVVIK RLKPANANSN
60 70 80 90 100
TSTELIQKLF EKEASVLEDL GEHNSQIPKL YSYFSNDNEF YLVQEYIQGV
110 120 130 140 150
SLNEIAPISS EQAKTILSSL LTTLKYIHSK GIIHRDIKPE NIILRDSDHL
160 170 180 190 200
PVLIDFGAVK ETMGAVTLGS GSTVSSVVIG TRGFMAPEQS SGRSVFSTDL
210 220 230 240 250
YALGLTIIYT LTKKLPVEFS SDQQTGQLDW QSHVSKIDSV LAKVINKAIE
260 270 280 290 300
MEPSRRYSSA EAMYQALHSL ISSGAEPALP METVRVAPSN EFLVTRSSTK
310 320 330 340 350
TAETVVKPVG NSHNNYSNNN GKSKIATLLT VLIGIIVVTA GLGGGFIITQ
360 370 380 390 400
QIKEAEARAA QAEKEKQEAE QKRIEAEQKI AENEKRQREL EQKRVEEERQ
410 420 430 440 450
RLAAEAERAK QERQRLAAER QRVQVLANQA KAMASGASAT IGGIPGSKNI
460 470 480 490 500
RSGPGTDYGV ITQGYTGEGL DILDSSTDSS GHVWYKVYHY GSGSTGWIAS

QLVNF
Length:505
Mass (Da):55,213
Last modified:October 1, 1996 - v1
Checksum:iC4F12A1886C4D51C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046600 Genomic DNA. Translation: BAB17036.1.
BA000022 Genomic DNA. Translation: BAA10726.1.
PIRiS77034.

Genome annotation databases

EnsemblBacteriaiBAA10726; BAA10726; BAA10726.
KEGGisyy:SYNGTS_2763.
syz:MYO_127890.
PATRICi23843054. VBISynSp132158_3065.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046600 Genomic DNA. Translation: BAB17036.1.
BA000022 Genomic DNA. Translation: BAA10726.1.
PIRiS77034.

3D structure databases

ProteinModelPortaliP54735.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP54735. 14 interactions.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA10726; BAA10726; BAA10726.
KEGGisyy:SYNGTS_2763.
syz:MYO_127890.
PATRICi23843054. VBISynSp132158_3065.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000054695.
InParanoidiP54735.
KOiK08884.
OMAiFNDKESE.
OrthoDBiEOG6BKJ4J.
PhylomeDBiP54735.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR003646. SH3-like_bac-type.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF08239. SH3_3. 1 hit.
[Graphical view]
SMARTiSM00287. SH3b. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Biochemical examination of the potential eukaryotic-type protein kinase genes in the complete genome of the unicellular Cyanobacterium synechocystis sp. PCC 6803."
    Kamei A., Yuasa T., Geng X., Ikeuchi M.
    DNA Res. 9:71-78(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
    Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
    DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27184 / PCC 6803 / N-1.
  3. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiSPKD_SYNY3
AccessioniPrimary (citable) accession number: P54735
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: July 22, 2015
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.