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P54735

- SPKD_SYNY3

UniProt

P54735 - SPKD_SYNY3

Protein

Serine/threonine-protein kinase D

Gene

spkD

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei40 – 401ATPPROSITE-ProRule annotation
    Active sitei136 – 1361Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi15 – 239ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein kinase D (EC:2.7.11.1)
    Gene namesi
    Name:spkD
    Ordered Locus Names:sll0776
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 505505Serine/threonine-protein kinase DPRO_0000171242Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    IntActiP54735. 14 interactions.
    STRINGi1148.sll0776.

    Structurei

    3D structure databases

    ProteinModelPortaliP54735.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini9 – 271263Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000054695.
    KOiK08884.
    OMAiFLITEYI.
    OrthoDBiEOG6BKJ4J.
    PhylomeDBiP54735.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    IPR003646. SH3-like_bac-type.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    PF08239. SH3_3. 1 hit.
    [Graphical view]
    SMARTiSM00287. SH3b. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P54735-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNVQVLDRYE IVKSLGSGGF GDTFLAKDTQ IPSQKLVVIK RLKPANANSN    50
    TSTELIQKLF EKEASVLEDL GEHNSQIPKL YSYFSNDNEF YLVQEYIQGV 100
    SLNEIAPISS EQAKTILSSL LTTLKYIHSK GIIHRDIKPE NIILRDSDHL 150
    PVLIDFGAVK ETMGAVTLGS GSTVSSVVIG TRGFMAPEQS SGRSVFSTDL 200
    YALGLTIIYT LTKKLPVEFS SDQQTGQLDW QSHVSKIDSV LAKVINKAIE 250
    MEPSRRYSSA EAMYQALHSL ISSGAEPALP METVRVAPSN EFLVTRSSTK 300
    TAETVVKPVG NSHNNYSNNN GKSKIATLLT VLIGIIVVTA GLGGGFIITQ 350
    QIKEAEARAA QAEKEKQEAE QKRIEAEQKI AENEKRQREL EQKRVEEERQ 400
    RLAAEAERAK QERQRLAAER QRVQVLANQA KAMASGASAT IGGIPGSKNI 450
    RSGPGTDYGV ITQGYTGEGL DILDSSTDSS GHVWYKVYHY GSGSTGWIAS 500
    QLVNF 505
    Length:505
    Mass (Da):55,213
    Last modified:October 1, 1996 - v1
    Checksum:iC4F12A1886C4D51C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB046600 Genomic DNA. Translation: BAB17036.1.
    BA000022 Genomic DNA. Translation: BAA10726.1.
    PIRiS77034.
    RefSeqiNP_442655.1. NC_000911.1.
    YP_005652716.1. NC_017277.1.
    YP_007452531.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA10726; BAA10726; BAA10726.
    GeneIDi952202.
    KEGGisyn:sll0776.
    syy:SYNGTS_2763.
    syz:MYO_127890.
    PATRICi23843054. VBISynSp132158_3065.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB046600 Genomic DNA. Translation: BAB17036.1 .
    BA000022 Genomic DNA. Translation: BAA10726.1 .
    PIRi S77034.
    RefSeqi NP_442655.1. NC_000911.1.
    YP_005652716.1. NC_017277.1.
    YP_007452531.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P54735.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P54735. 14 interactions.
    STRINGi 1148.sll0776.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA10726 ; BAA10726 ; BAA10726 .
    GeneIDi 952202.
    KEGGi syn:sll0776.
    syy:SYNGTS_2763.
    syz:MYO_127890.
    PATRICi 23843054. VBISynSp132158_3065.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000054695.
    KOi K08884.
    OMAi FLITEYI.
    OrthoDBi EOG6BKJ4J.
    PhylomeDBi P54735.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    IPR003646. SH3-like_bac-type.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    PF08239. SH3_3. 1 hit.
    [Graphical view ]
    SMARTi SM00287. SH3b. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Biochemical examination of the potential eukaryotic-type protein kinase genes in the complete genome of the unicellular Cyanobacterium synechocystis sp. PCC 6803."
      Kamei A., Yuasa T., Geng X., Ikeuchi M.
      DNA Res. 9:71-78(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
    2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
      Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
      DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27184 / PCC 6803 / N-1.
    3. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiSPKD_SYNY3
    AccessioniPrimary (citable) accession number: P54735
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 100 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3