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P54734 (PKNA_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PknA

EC=2.7.11.1
Gene names
Name:pknA
Ordered Locus Names:alr4366
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaNostocalesNostocaceaeNostoc

Protein attributes

Sequence length564 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Probably required for both normal cellular growth and differentiation. Inactivation of pknA leads to colonies that appear light green and rough in the absence of combined nitrogen.

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 564564Serine/threonine-protein kinase PknA
PRO_0000171181

Regions

Domain9 – 271263Protein kinase
Nucleotide binding15 – 239ATP By similarity

Sites

Active site1391Proton acceptor By similarity
Binding site401ATP By similarity

Experimental info

Sequence conflict2651E → Q in AAB41116. Ref.1
Sequence conflict5221A → R in AAB41116. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P54734 [UniParc].

Last modified January 23, 2002. Version 2.
Checksum: AD0485E7AC69E785

FASTA56462,385
        10         20         30         40         50         60 
MEQLLDNRYR VIKTLGSGGF GETFLAEDSQ MPSNRRCVVK QLRPIHNNPQ IYQLVQERFQ 

        70         80         90        100        110        120 
REAAILEDLG SYSGQIPTLY AYFQSNTQFY VVQEWVEGDT LTAKLKQQGV LSESAVRDIL 

       130        140        150        160        170        180 
INLLPVLEYV HSKRIIHRDI KPDNIILRHR DGKPVLIDFG AVRESMGTVI NSQGNPTSSI 

       190        200        210        220        230        240 
VIGTPGYMPS EQAAGRPVYS SDLYSLGLTA IYLLTGKQPQ ELETEPHSGE IIWHRYALNI 

       250        260        270        280        290        300 
SPTLAAVIDR AIAYHPRERF TTAREMLEAL QLGVVSYPPT VPYQQPQSSP TVPYQQPPVV 

       310        320        330        340        350        360 
TTPPFATQTN TVAVSPGTAP TPQPINHNNS NKGILMGSLI AGGLIGASVV IGFALTRPNQ 

       370        380        390        400        410        420 
PVTQTTSLPS ETTISNNDTP TVEPSPTDTP ETPISQTVTQ DPTPQASVRF PINSRPFTTP 

       430        440        450        460        470        480 
IDSKPRNTTE PTTSVPQPTT PSEPQITTPV EATDRPSPEQ AVQNYYETIN QGEYSTAWNL 

       490        500        510        520        530        540 
LASSFQNNRK LHPRGYDSYL DWWGGQVENV DVEQVSLLKA NADTATVNAR LRYFMKSGRQ 

       550        560 
SSSSVRFSLV WDADNNRWVV SGAR 

« Hide

References

« Hide 'large scale' references
[1]"A gene encoding a protein related to eukaryotic protein kinases from the filamentous heterocystous cyanobacterium Anabaena PCC 7120."
Zhang C.C.
Proc. Natl. Acad. Sci. U.S.A. 90:11840-11844(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00484 Genomic DNA. Translation: AAB41116.1.
BA000019 Genomic DNA. Translation: BAB76065.1.
PIRAF2351.
RefSeqNP_488406.1. NC_003272.1.

3D structure databases

ProteinModelPortalP54734.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING103690.alr4366.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB76065; BAB76065; BAB76065.
GeneID1107967.
KEGGana:alr4366.
PATRIC22779306. VBINosSp37423_5100.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000035389.
KOK08884.
OMASTAYLVM.
OrthoDBEOG6RC3K8.
ProtClustDBCLSK2393641.

Enzyme and pathway databases

BRENDA2.7.11.1. 319.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKNA_NOSS1
AccessionPrimary (citable) accession number: P54734
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2002
Last modified: November 13, 2013
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families