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Protein

UBX domain-containing protein 4

Gene

UBX4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.By similarity

Miscellaneous

Present with 3570 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • protein-containing complex binding Source: SGD

GO - Biological processi

  • sporulation resulting in formation of a cellular spore Source: SGD
  • ubiquitin-dependent ERAD pathway Source: SGD

Keywordsi

Biological processUbl conjugation pathway

Enzyme and pathway databases

BioCyciYEAST:G3O-32769-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UBX domain-containing protein 4
Gene namesi
Name:UBX4
Ordered Locus Names:YMR067C
ORF Names:YM9916.06C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR067C
SGDiS000004671 UBX4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002110011 – 416UBX domain-containing protein 4Add BLAST416

Proteomic databases

MaxQBiP54730
PaxDbiP54730
PRIDEiP54730

PTM databases

iPTMnetiP54730

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CDC48P256945EBI-28127,EBI-4308

Protein-protein interaction databases

BioGridi35242, 184 interactors
DIPiDIP-5070N
IntActiP54730, 1 interactor
MINTiP54730
STRINGi4932.YMR067C

Structurei

3D structure databases

ProteinModelPortaliP54730
SMRiP54730
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini273 – 350UBXPROSITE-ProRule annotationAdd BLAST78

Phylogenomic databases

HOGENOMiHOG000154766
InParanoidiP54730
OMAiPKWMKLS
OrthoDBiEOG092C3YGY

Family and domain databases

InterProiView protein in InterPro
IPR021569 TUG-UBL1
IPR029071 Ubiquitin-like_domsf
IPR001012 UBX_dom
PfamiView protein in Pfam
PF11470 TUG-UBL1, 1 hit
PF00789 UBX, 1 hit
SMARTiView protein in SMART
SM00166 UBX, 1 hit
SUPFAMiSSF54236 SSF54236, 2 hits
PROSITEiView protein in PROSITE
PS50033 UBX, 1 hit

Sequencei

Sequence statusi: Complete.

P54730-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPMVTVKYNF QLFKCKVSLN STLNDVLHQS IQFFQLHTSS NDWSLIHLDK
60 70 80 90 100
PVPLDLPWRL LNLPTGVNLE LSKSSNFPVA NKTNREDIPF NTIKIRFQIP
110 120 130 140 150
GRDSVVKEMP SDQPIAPILR QMSGAAGDDF KIQVFSKIIE FKTIKDENLT
160 170 180 190 200
LENLGIQEPS SVRLIFNNTS HSEGISANSA IHPKQTPPTM TNPETVASLP
210 220 230 240 250
PHELHKPSVF LPSDEPLAVI KDQIEDEEDY ELTVEQAKKY QKMLSSKAGT
260 270 280 290 300
LGGPILTKRL REQSANNLPK KNKAISECLL RVKFPDRSHI QIAFKPNEDM
310 320 330 340 350
RTVYNVVSQF LIDENMPFTL NQSHPFKPLA KDDKKLLDDL EFGSKTMLLF
360 370 380 390 400
ETNSNSNGPL IKAHLLEDAQ KITHETRTTP SVNTINKSNP QGPSDNATSI
410
KKTLNRVPKW MKLSKK
Length:416
Mass (Da):46,965
Last modified:October 1, 1996 - v1
Checksum:i615E5F8EC1DCDD31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48952 Genomic DNA Translation: CAA88792.1
BK006946 Genomic DNA Translation: DAA09965.1
PIRiS52827
RefSeqiNP_013783.1, NM_001182565.1

Genome annotation databases

EnsemblFungiiYMR067C; YMR067C; YMR067C
GeneIDi855089
KEGGisce:YMR067C

Similar proteinsi

Entry informationi

Entry nameiUBX4_YEAST
AccessioniPrimary (citable) accession number: P54730
Secondary accession number(s): D6VZP1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health