Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P54730

- UBX4_YEAST

UniProt

P54730 - UBX4_YEAST

Protein

UBX domain-containing protein 4

Gene

UBX4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 104 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.By similarity

    GO - Molecular functioni

    1. protein binding Source: IntAct
    2. protein complex binding Source: SGD

    GO - Biological processi

    1. ER-associated ubiquitin-dependent protein catabolic process Source: SGD
    2. sporulation resulting in formation of a cellular spore Source: SGD

    Keywords - Biological processi

    Ubl conjugation pathway

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32769-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UBX domain-containing protein 4
    Gene namesi
    Name:UBX4
    Ordered Locus Names:YMR067C
    ORF Names:YM9916.06C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIII

    Organism-specific databases

    CYGDiYMR067c.
    SGDiS000004671. UBX4.

    Subcellular locationi

    Nucleus 1 Publication. Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. extrinsic component of membrane Source: SGD
    3. nucleus Source: SGD

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 416416UBX domain-containing protein 4PRO_0000211001Add
    BLAST

    Proteomic databases

    MaxQBiP54730.
    PaxDbiP54730.
    PeptideAtlasiP54730.

    Expressioni

    Gene expression databases

    GenevestigatoriP54730.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    CDC48P256945EBI-28127,EBI-4308

    Protein-protein interaction databases

    BioGridi35242. 66 interactions.
    DIPiDIP-5070N.
    IntActiP54730. 2 interactions.
    MINTiMINT-491552.
    STRINGi4932.YMR067C.

    Structurei

    3D structure databases

    ProteinModelPortaliP54730.
    SMRiP54730. Positions 2-78, 89-164.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini273 – 35078UBXPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 UBX domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG317887.
    HOGENOMiHOG000154766.
    OMAiISECLLR.
    OrthoDBiEOG77Q567.

    Family and domain databases

    InterProiIPR021569. TUG/UBX4.
    IPR029071. Ubiquitin-rel_dom.
    IPR001012. UBX_dom.
    [Graphical view]
    PfamiPF11470. TUG-UBL1. 1 hit.
    PF00789. UBX. 1 hit.
    [Graphical view]
    SMARTiSM00166. UBX. 1 hit.
    [Graphical view]
    SUPFAMiSSF54236. SSF54236. 2 hits.
    PROSITEiPS50033. UBX. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P54730-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPMVTVKYNF QLFKCKVSLN STLNDVLHQS IQFFQLHTSS NDWSLIHLDK    50
    PVPLDLPWRL LNLPTGVNLE LSKSSNFPVA NKTNREDIPF NTIKIRFQIP 100
    GRDSVVKEMP SDQPIAPILR QMSGAAGDDF KIQVFSKIIE FKTIKDENLT 150
    LENLGIQEPS SVRLIFNNTS HSEGISANSA IHPKQTPPTM TNPETVASLP 200
    PHELHKPSVF LPSDEPLAVI KDQIEDEEDY ELTVEQAKKY QKMLSSKAGT 250
    LGGPILTKRL REQSANNLPK KNKAISECLL RVKFPDRSHI QIAFKPNEDM 300
    RTVYNVVSQF LIDENMPFTL NQSHPFKPLA KDDKKLLDDL EFGSKTMLLF 350
    ETNSNSNGPL IKAHLLEDAQ KITHETRTTP SVNTINKSNP QGPSDNATSI 400
    KKTLNRVPKW MKLSKK 416
    Length:416
    Mass (Da):46,965
    Last modified:October 1, 1996 - v1
    Checksum:i615E5F8EC1DCDD31
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48952 Genomic DNA. Translation: CAA88792.1.
    BK006946 Genomic DNA. Translation: DAA09965.1.
    PIRiS52827.
    RefSeqiNP_013783.1. NM_001182565.1.

    Genome annotation databases

    EnsemblFungiiYMR067C; YMR067C; YMR067C.
    GeneIDi855089.
    KEGGisce:YMR067C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48952 Genomic DNA. Translation: CAA88792.1 .
    BK006946 Genomic DNA. Translation: DAA09965.1 .
    PIRi S52827.
    RefSeqi NP_013783.1. NM_001182565.1.

    3D structure databases

    ProteinModelPortali P54730.
    SMRi P54730. Positions 2-78, 89-164.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35242. 66 interactions.
    DIPi DIP-5070N.
    IntActi P54730. 2 interactions.
    MINTi MINT-491552.
    STRINGi 4932.YMR067C.

    Proteomic databases

    MaxQBi P54730.
    PaxDbi P54730.
    PeptideAtlasi P54730.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YMR067C ; YMR067C ; YMR067C .
    GeneIDi 855089.
    KEGGi sce:YMR067C.

    Organism-specific databases

    CYGDi YMR067c.
    SGDi S000004671. UBX4.

    Phylogenomic databases

    eggNOGi NOG317887.
    HOGENOMi HOG000154766.
    OMAi ISECLLR.
    OrthoDBi EOG77Q567.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32769-MONOMER.

    Miscellaneous databases

    NextBioi 978390.

    Gene expression databases

    Genevestigatori P54730.

    Family and domain databases

    InterProi IPR021569. TUG/UBX4.
    IPR029071. Ubiquitin-rel_dom.
    IPR001012. UBX_dom.
    [Graphical view ]
    Pfami PF11470. TUG-UBL1. 1 hit.
    PF00789. UBX. 1 hit.
    [Graphical view ]
    SMARTi SM00166. UBX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54236. SSF54236. 2 hits.
    PROSITEi PS50033. UBX. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    5. "Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation."
      Schuberth C., Richly H., Rumpf S., Buchberger A.
      EMBO Rep. 5:818-824(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH CDC48.

    Entry informationi

    Entry nameiUBX4_YEAST
    AccessioniPrimary (citable) accession number: P54730
    Secondary accession number(s): D6VZP1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 104 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 3570 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XIII
      Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

    External Data

    Dasty 3