Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Flagellar biosynthetic protein FliP

Gene

fliP

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Plays a role in the flagellum-specific transport system.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport

Protein family/group databases

TCDBi3.A.6.2.1. the type iii (virulence-related) secretory pathway (iiisp) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar biosynthetic protein FliP
Gene namesi
Name:fliP
Synonyms:flaR
Ordered Locus Names:STM1979
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei45 – 65HelicalSequence analysisAdd BLAST21
Transmembranei88 – 108HelicalSequence analysisAdd BLAST21
Transmembranei185 – 205HelicalSequence analysisAdd BLAST21
Transmembranei209 – 229HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 211 PublicationAdd BLAST21
ChainiPRO_000000953622 – 245Flagellar biosynthetic protein FliPAdd BLAST224

Proteomic databases

PaxDbiP54700.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM1979.

Structurei

3D structure databases

ProteinModelPortaliP54700.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FliP/MopC/SpaP family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CN7. Bacteria.
COG1338. LUCA.
HOGENOMiHOG000253558.
KOiK02419.
OMAiMPPNQIL.
PhylomeDBiP54700.

Family and domain databases

InterProiIPR005837. FliP.
IPR005838. T3SS_IM_P.
[Graphical view]
PANTHERiPTHR30587:SF0. PTHR30587:SF0. 1 hit.
PfamiPF00813. FliP. 1 hit.
[Graphical view]
PRINTSiPR00951. FLGBIOSNFLIP.
PR01302. TYPE3IMPPROT.
TIGRFAMsiTIGR01103. fliP. 1 hit.
PROSITEiPS01060. FLIP_1. 1 hit.
PS01061. FLIP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P54700-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRLLFLSLA GLWLFSPAAA AQLPGLISQP LAGGGQSWSL SVQTLVFITS
60 70 80 90 100
LTFLPAILLM MTSFTRIIIV FGLLRNALGT PSAPPNQVLL GLALFLTFFI
110 120 130 140 150
MSPVIDKIYV DAYQPFSEQK ISMQEALDKG AQPLRAFMLR QTREADLALF
160 170 180 190 200
ARLANSGPLQ GPEAVPMRIL LPAYVTSELK TAFQIGFTIF IPFLIIDLVI
210 220 230 240
ASVLMALGMM MVPPATIALP FKLMLFVLVD GWQLLMGSLA QSFYS
Length:245
Mass (Da):26,787
Last modified:October 1, 1996 - v1
Checksum:iC9A4241F0653A4D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L49021 Genomic DNA. Translation: AAB81319.1.
AE006468 Genomic DNA. Translation: AAL20891.1.
PIRiS78698.
RefSeqiNP_460932.1. NC_003197.1.
WP_001253410.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL20891; AAL20891; STM1979.
GeneIDi1253500.
KEGGistm:STM1979.
PATRICi32382521. VBISalEnt20916_2096.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L49021 Genomic DNA. Translation: AAB81319.1.
AE006468 Genomic DNA. Translation: AAL20891.1.
PIRiS78698.
RefSeqiNP_460932.1. NC_003197.1.
WP_001253410.1. NC_003197.1.

3D structure databases

ProteinModelPortaliP54700.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM1979.

Protein family/group databases

TCDBi3.A.6.2.1. the type iii (virulence-related) secretory pathway (iiisp) family.

Proteomic databases

PaxDbiP54700.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL20891; AAL20891; STM1979.
GeneIDi1253500.
KEGGistm:STM1979.
PATRICi32382521. VBISalEnt20916_2096.

Phylogenomic databases

eggNOGiENOG4105CN7. Bacteria.
COG1338. LUCA.
HOGENOMiHOG000253558.
KOiK02419.
OMAiMPPNQIL.
PhylomeDBiP54700.

Family and domain databases

InterProiIPR005837. FliP.
IPR005838. T3SS_IM_P.
[Graphical view]
PANTHERiPTHR30587:SF0. PTHR30587:SF0. 1 hit.
PfamiPF00813. FliP. 1 hit.
[Graphical view]
PRINTSiPR00951. FLGBIOSNFLIP.
PR01302. TYPE3IMPPROT.
TIGRFAMsiTIGR01103. fliP. 1 hit.
PROSITEiPS01060. FLIP_1. 1 hit.
PS01061. FLIP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFLIP_SALTY
AccessioniPrimary (citable) accession number: P54700
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

For insertion of FliP into the membrane, cleavage of the signal peptide is important kinetically but not absolutely required.

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.