Myosin-J heavy chain

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• actin-dependent ATPase activity Source: dictyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18650439
• actin filament binding Source: dictyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18650439
• ADP binding Source: dictyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18650439
• ATP binding Source: dictyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18650439
• calmodulin binding Source: UniProtKB-KW
• microfilament motor activity Source: dictyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18650439

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• actin-myosin filament sliding Source: dictyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18650439
• establishment of contractile vacuole localization Source: dictyBase <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • 19687255

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• actomyosin Source: dictyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18650439
• contractile vacuole Source: dictyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18650439
• myosin complex Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechⁱ

Chemistry databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">‘Interaction’</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• actin filament binding Source: dictyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18650439
• calmodulin binding Source: UniProtKB-KW

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Region

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the ‘Sequence’ section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MTTSTIENGA SSPIIVSSST PKLYQEGAGV WIPDQELGWI GADVIEHSET 
        60         70         80         90        100
SADQVLVRTE DDREVKIPLS KVFQKNPDIL EGVDDLSFLS HLHEPAILHN 
       110        120        130        140        150
LHHRYNLNQI YTYIGKILIA INPYTSLPLY GKEMISAYYG KQLGTLAPHV 
       160        170        180        190        200
YAVAEDAFKD MRYDGTSQSI LVSGESGAGK TETTKFLLQY FAAMGNMIKE 
       210        220        230        240        250
STSSSSINGI NTSSDGIPVT PPPSPMKKSP VDKSVEERVL ESTPLLEAFG 
       260        270        280        290        300
NAKTLRNDNS SRFGKFIEIH FNEMGSIIGA KILTYLLEKS RIVRQVYNER 
       310        320        330        340        350
NYHIFYQLLS GASEELKEKL NLKTIEEYSY LNKSGCFEIE GVSDEEHFNK 
       360        370        380        390        400
TCHAMQVAGI TLVEQENVFR ILSAILLIGN FEFENIAGSN DDSCQLIDRD 
       410        420        430        440        450
PLEKVSVLLG CAQPDELLNS MLTRKVVTGK ESYISHNTKE RAENARDSLS 
       460        470        480        490        500
MFLYGMMFDW LVVKINSSMS ISTQQKSKSF IGVLDIYGFE SFEVNGFEQF 
       510        520        530        540        550
CINYANEKLQ QLFNQHVFKE EQQEYIKEKI DWSYIDFNDN QDTLDLIEKK 
       560        570        580        590        600
PICILTLLDE ETMFPKATPQ TLATKLYSKM TSHSKFEKPR FSSTAFTINH 
       610        620        630        640        650
YAGKVTYETD QFLDKNKDFI IPEQISILQR SNFSFIKVLM SHSDKFTQSP 
       660        670        680        690        700
GGHPQGNGGP TSSNTKGTSG SSSMKFLSVG SQFSTSLATL MKTISTTTPH 
       710        720        730        740        750
YVRCIKPNPE KLPQTFNKQD VIHQLRCGGV MESVRICCAG FPTRRLLSEF 
       760        770        780        790        800
YQRYKILYVK DINTGSGGGK KGSNNNKIKD PKILVQNLLT GIELSDDKYK 
       810        820        830        840        850
IGLTKVFLRA GQLASLEDMR LEQLDRSATV IQKRWKGYLY RKRYKQLRDA 
       860        870        880        890        900
SLIIQTKLRS VHAKQQLSAL QRTHSAILIQ KVWRAHRDRV QYQKIRDASL 
       910        920        930        940        950
QLQTVMRRHL FSEQVHRERC ENAAIILQTK IRQILSKREV DKKLRGIILI 
       960        970        980        990       1000
QARWRMKLAK RVYIQLRAEA RSLRTVQEQK NKLQEKLEEL QWRLTSEAKR 
      1010       1020       1030       1040       1050
KQQLEDQKVK SDTTISELSS NNDHLELQLS EIQLKYQELD KSNQSSQLQL 
      1060       1070       1080       1090       1100
SECLSKLEEQ TQQLDHSSKL NKKLEKDLSD QHDSIEKLQS QFNETEQQLQ 
      1110       1120       1130       1140       1150
QFKQQSEELS SKLSKTTQQL DFNKQEFDRL SQERDTDNTN NQLEIQQLKK 
      1160       1170       1180       1190       1200
ANSTLEEDYF SLSGIRDNLE RQVLELRDEN QLIKERLDSL GQQSSQFQSG 
      1210       1220       1230       1240       1250
AALEKQQLEQ LVQEQSEQLI KLSSEKLGSE EEAKKQINQL ELELTDHKSK 
      1260       1270       1280       1290       1300
LQIQLQLTEQ SNEKIKKLKG KLEEYQDEKK QLQQELERIK QSKQSVEDEK 
      1310       1320       1330       1340       1350
NSLITQLTTV KFESTQVSTN VSHQKEKITT LKSTIEELNK SIGKLQAEQK 
      1360       1370       1380       1390       1400
NKDDEIRKIQ FELNDQKQQF TRQTKEFSDL QSQQSIDRQK SEITIHSLER 
      1410       1420       1430       1440       1450
TNETLKSDFE RVQQSLKQQE RDCQQYKDTI NRLENEVKQL TQLKERFENE 
      1460       1470       1480       1490       1500
FFVAKEQNSN QTQESVYLKE VTTQMQQNQS RIERELEEKK QHITRIDDER 
      1510       1520       1530       1540       1550
DELKKQLTQL QQQHEQSSTQ LLLAQNELER LRKKELKYKE RGHETSKQQD 
      1560       1570       1580       1590       1600
QFNMEIQSLR ITNNDQLKSL QDYEQEKKKL KDKLSSSKQE AQQQRESIIK 
      1610       1620       1630       1640       1650
MDAELSAIKQ HSQWVENSFT DMKQRNQELI ESSALYKQQL LQQTSTIDST 
      1660       1670       1680       1690       1700
IKEKENEISK LQQQLETSNQ QLHQLKEELN SMKQSNQLES TEQSKQLNQL 
      1710       1720       1730       1740       1750
IQENQQLKSV TNEISKQLDD AVFENQKINN TIKEQEIKSK RMSVELQQHI 
      1760       1770       1780       1790       1800
DEGKQQEIQQ LQSTIAQLKQ QQQSETDRLE KEIQQMKRER ETQMKLVEST 
      1810       1820       1830       1840       1850
KLNYHMLEDR MELYRNVMEI IDYKETEWEK LARLAGCKEL DTKLLSDFLL 
      1860       1870       1880       1890       1900
SCKLEHTSLG SQMWFHQIDY WCPYERDSSK GIFYGIIRSI VDFTIKNFDD 
      1910       1920       1930       1940       1950
VDLLSYLLAC CSLTLFLYKK NLVKHLNGAN SIMPIIPTLG DLEELNERLS 
      1960       1970       1980       1990       2000
HQSLTTSGKF SGGGGGGGID FIDQLQQSTG ITFGLIFKAT TLKLSPLVDG 
      2010       2020       2030       2040       2050
AILNENYNKK LTSISASSFG SGSFGLGSNG VGSVLSIELI TTYLSSIITI 
      2060       2070       2080       2090       2100
FQHRMVHFTL SQRFFNQVFC WIGALIMKGF MLRQTFCTET FATFVKTKID 
      2110       2120       2130       2140       2150
FLTRWADDIG NVWVGDVANA FQQVREVINV LNIKDKEKII DDKIRKQYCP 
      2160       2170       2180       2190       2200
TLNSNQLKQV LSLFSPGEFG GKRVSAKVIA SICPPNKSSA GQSFVQDENK 
      2210       2220       2230       2240 
LNTIPIDSLH YLEIQDIKTL SLPLSIRQTI ETEIINLKQQ IACKK 

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

Documents

1. Dictyostelium discoideum
   Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
2. SIMILARITY comments
   Index of protein domains and families