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P54636 (VP2_LORDV) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene names
ORF Names:ORF3
OrganismLordsdale virus (strain GII/Human/United Kingdom/Lordsdale/1993) (Human enteric calicivirus) (Hu/NV/LD/1993/UK) [Complete proteome]
Taxonomic identifier82658 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeNorovirus
Virus hostHomo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Minor structural protein present in one or two copies per virion. Stabilizes capsid protein VP1 by protecting it from disassembly and degradation. May play a role in RNA genome packaging By similarity.

Subcellular location

Virion. Host cytoplasm By similarity.

Miscellaneous

Translated by a ribosomal termination-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Sequence similarities

Belongs to the norovirus VP2 family.

Ontologies

Keywords
   Cellular componentHost cytoplasm
Virion
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componenthost cell cytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

virion

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 268268Protein VP2
PRO_0000100130

Sequences

Sequence LengthMass (Da)Tools
P54636 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: FE6F19E4D7D1587E

FASTA26828,458
        10         20         30         40         50         60 
MAGAFFAGLA SDVLGSGLGS LINAGAGAIN QKVEFENNRK LQQASFQFSS TLQQASFQHD 

        70         80         90        100        110        120 
KEMLQAQIEA TQKLQQDLMK VKQAVLLEGG FSTADAARGA INAPMTKALD WSGTRYWAPD 

       130        140        150        160        170        180 
ARVTTYNAGH FSTPQSLGAL TGRTNSRVSA PARSSPSALS NAPTATSLHS NQTVSTRLGS 

       190        200        210        220        230        240 
SAGSGTGVSS LSSAARTRSW VEDQNRNLSP FMRGALNTSF VTPPSSRSSS QSTVSTVPKE 

       250        260 
ILDSWTGAFN TRRQPLFAHI RKRGESRV 

« Hide

References

[1]"Human enteric Caliciviridae: the complete genome sequence and expression of virus-like particles from a genetic group II small round structured virus."
Dingle K.E., Lambden P.R., Caul E.O., Clarke I.N.
J. Gen. Virol. 76:2349-2355(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X86557 Genomic RNA. Translation: CAA60256.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004278. RNA_pol/capsid.
[Graphical view]
PfamPF03035. RNA_capsid. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVP2_LORDV
AccessionPrimary (citable) accession number: P54636
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 29, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families