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P54636

- VP2_LORDV

UniProt

P54636 - VP2_LORDV

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Protein
Protein VP2
Gene
ORF3
Organism
Lordsdale virus (strain GII/Human/United Kingdom/Lordsdale/1993) (Human enteric calicivirus) (Hu/NV/LD/1993/UK)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Minor structural protein present in one or two copies per virion. Stabilizes capsid protein VP1 by protecting it from disassembly and degradation. May play a role in RNA genome packaging By similarity.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene namesi
ORF Names:ORF3
OrganismiLordsdale virus (strain GII/Human/United Kingdom/Lordsdale/1993) (Human enteric calicivirus) (Hu/NV/LD/1993/UK)
Taxonomic identifieri82658 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeNorovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
ProteomesiUP000007767: Genome

Subcellular locationi

Virion. Host cytoplasm By similarity

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-SubCell
  2. virion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 268268Protein VP2
PRO_0000100130Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the norovirus VP2 family.

Family and domain databases

InterProiIPR004278. RNA_pol/capsid.
[Graphical view]
PfamiPF03035. RNA_capsid. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P54636-1 [UniParc]FASTAAdd to Basket

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MAGAFFAGLA SDVLGSGLGS LINAGAGAIN QKVEFENNRK LQQASFQFSS    50
TLQQASFQHD KEMLQAQIEA TQKLQQDLMK VKQAVLLEGG FSTADAARGA 100
INAPMTKALD WSGTRYWAPD ARVTTYNAGH FSTPQSLGAL TGRTNSRVSA 150
PARSSPSALS NAPTATSLHS NQTVSTRLGS SAGSGTGVSS LSSAARTRSW 200
VEDQNRNLSP FMRGALNTSF VTPPSSRSSS QSTVSTVPKE ILDSWTGAFN 250
TRRQPLFAHI RKRGESRV 268
Length:268
Mass (Da):28,458
Last modified:October 1, 1996 - v1
Checksum:iFE6F19E4D7D1587E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X86557 Genomic RNA. Translation: CAA60256.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X86557 Genomic RNA. Translation: CAA60256.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR004278. RNA_pol/capsid.
[Graphical view ]
Pfami PF03035. RNA_capsid. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Human enteric Caliciviridae: the complete genome sequence and expression of virus-like particles from a genetic group II small round structured virus."
    Dingle K.E., Lambden P.R., Caul E.O., Clarke I.N.
    J. Gen. Virol. 76:2349-2355(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiVP2_LORDV
AccessioniPrimary (citable) accession number: P54636
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 29, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Translated by a ribosomal termination-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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