Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

14-3-3-like protein

Gene

fttB

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • myosin II heavy chain binding Source: dictyBase
  • protein domain specific binding Source: InterPro

GO - Biological processi

  • cleavage furrow ingression Source: dictyBase
  • cortical cytoskeleton organization Source: dictyBase
  • microtubule cytoskeleton organization Source: dictyBase
  • positive regulation of cytokinesis Source: dictyBase
  • protein localization Source: dictyBase
  • response to bacterium Source: dictyBase

Enzyme and pathway databases

ReactomeiR-DDI-1445148. Translocation of GLUT4 to the plasma membrane.
R-DDI-3371453. Regulation of HSF1-mediated heat shock response.
R-DDI-3371511. HSF1 activation.
R-DDI-5625740. RHO GTPases activate PKNs.
R-DDI-5628897. TP53 Regulates Metabolic Genes.
R-DDI-75035. Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex.
R-DDI-8876198. RAB GEFs exchange GTP for GDP on RABs.

Names & Taxonomyi

Protein namesi
Recommended name:
14-3-3-like protein
Gene namesi
Name:fttB
ORF Names:DDB_G0269138
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0269138. fttB.

Subcellular locationi

GO - Cellular componenti

  • cell cortex Source: dictyBase
  • centrosome Source: dictyBase
  • nucleus Source: dictyBase
  • phagocytic vesicle Source: dictyBase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000586491 – 25214-3-3-like proteinAdd BLAST252

Proteomic databases

PaxDbiP54632.
PRIDEiP54632.

Interactioni

GO - Molecular functioni

  • myosin II heavy chain binding Source: dictyBase
  • protein domain specific binding Source: InterPro

Protein-protein interaction databases

STRINGi44689.DDB0232938.

Structurei

3D structure databases

ProteinModelPortaliP54632.
SMRiP54632.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 14-3-3 family.Curated

Phylogenomic databases

eggNOGiKOG0841. Eukaryota.
COG5040. LUCA.
InParanoidiP54632.
KOiK06630.
OMAiIPCATTG.
PhylomeDBiP54632.

Family and domain databases

Gene3Di1.20.190.20. 1 hit.
InterProiView protein in InterPro
IPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR036815. 14-3-3_dom_sf.
IPR023410. 14-3-3_domain.
PANTHERiPTHR18860. PTHR18860. 1 hit.
PfamiView protein in Pfam
PF00244. 14-3-3. 1 hit.
PIRSFiPIRSF000868. 14-3-3. 1 hit.
PRINTSiPR00305. 1433ZETA.
SMARTiView protein in SMART
SM00101. 14_3_3. 1 hit.
SUPFAMiSSF48445. SSF48445. 1 hit.
PROSITEiView protein in PROSITE
PS00796. 1433_1. 1 hit.
PS00797. 1433_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P54632-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTREENVYMA KLAEQAERYE EMVEAMKKVA ELDVELTVEE RNLLSVAYKN
60 70 80 90 100
VIGARRASWR IISSIEQKEE SKGNENHVKK IKEYKCKVEK ELTDICNDIL
110 120 130 140 150
EVLESHLIVS SASGESKVFY YKMKGDYFRY LAEFATGNPR KTSAESSLIA
160 170 180 190 200
YKAASDIAVT ELPPTHPIRL GLALNFSVFY YEILNSPDRA CNLAKTAFDD
210 220 230 240 250
AIAELDTLSE DSYKDSTLIM QLLRDNLTLW TSDVHNMEKN QDGDDDQNEP

GM
Length:252
Mass (Da):28,704
Last modified:December 4, 2007 - v2
Checksum:i30F03CC39D4E273D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti25A → T in CAA64814 (PubMed:9223628).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95568 mRNA. Translation: CAA64814.1.
AAFI02000005 Genomic DNA. Translation: EAS66939.1.
RefSeqiXP_001134475.1. XM_001134475.1.

Genome annotation databases

EnsemblProtistsiEAS66939; EAS66939; DDB_G0269138.
GeneIDi8617398.
KEGGiddi:DDB_G0269138.

Similar proteinsi

Entry informationi

Entry namei1433_DICDI
AccessioniPrimary (citable) accession number: P54632
Secondary accession number(s): Q1ZXP9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: December 4, 2007
Last modified: October 25, 2017
This is version 98 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families