Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P54495

- GLK_BACSU

UniProt

P54495 - GLK_BACSU

Protein

Glucokinase

Gene

glcK

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 2 (07 Jul 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + D-glucose = ADP + D-glucose 6-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glucokinase activity Source: CACAO

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBSUB:BSU24850-MONOMER.
    MetaCyc:MONOMER-5981.
    BRENDAi2.7.1.2. 700.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucokinase (EC:2.7.1.2)
    Alternative name(s):
    Glucose kinase
    Gene namesi
    Name:glcK
    Synonyms:yqgR
    Ordered Locus Names:BSU24850
    OrganismiBacillus subtilis (strain 168)
    Taxonomic identifieri224308 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001570: Chromosome

    Organism-specific databases

    GenoListiBSU24850. [Micado]

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 321321GlucokinasePRO_0000095676Add
    BLAST

    Proteomic databases

    PaxDbiP54495.

    Interactioni

    Protein-protein interaction databases

    STRINGi224308.BSU24850.

    Structurei

    3D structure databases

    ProteinModelPortaliP54495.
    SMRiP54495. Positions 3-315.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ROK (NagC/XylR) family.Curated

    Phylogenomic databases

    eggNOGiCOG1940.
    HOGENOMiHOG000150087.
    KOiK00845.
    OrthoDBiEOG6CGCDC.
    PhylomeDBiP54495.

    Family and domain databases

    InterProiIPR000600. ROK.
    IPR004654. ROK_glcA.
    [Graphical view]
    PfamiPF00480. ROK. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00744. ROK_glcA_fam. 1 hit.
    PROSITEiPS01125. ROK. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P54495-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDEIWFAGID LGGTTIKLAF INQYGEIQHK WEVPTDKTGD TITVTIAKTI    50
    DSKLDELQKP KHIIKYIGMG APGPVDMAAG VVYETVNLGW KNYALKNHLE 100
    TETGIPAVIE NDANIAALGE MWKGAGDGAK DVILVTLGTG VGGGIIANGE 150
    IVHGINGAGG EIGHICSIPE GGAPCNCGKT GCIETIASAT GIVRIAKEKI 200
    ANAKKTTRLK ATEQLSARDV FEAAGENDEI ALEVVDYVAK HLGLVLGNLA 250
    SSLNPSKIVL GGGVSRAGEL LRSKVEKTFR KCAFPRAAQA ADISIAALGN 300
    DAGVIGGAWI AKNEWLKHQN C 321
    Length:321
    Mass (Da):33,604
    Last modified:July 7, 2009 - v2
    Checksum:iF8162AE8BB49D3CD
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti152 – 1521V → L in BAA12521. (PubMed:8969508)Curated
    Sequence conflicti198 – 1981E → G in BAA12521. (PubMed:8969508)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D84432 Genomic DNA. Translation: BAA12521.1.
    AL009126 Genomic DNA. Translation: CAB14416.2.
    PIRiB69632.
    RefSeqiNP_390365.2. NC_000964.3.

    Genome annotation databases

    EnsemblBacteriaiCAB14416; CAB14416; BSU24850.
    GeneIDi938206.
    KEGGibsu:BSU24850.
    PATRICi18976806. VBIBacSub10457_2592.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D84432 Genomic DNA. Translation: BAA12521.1 .
    AL009126 Genomic DNA. Translation: CAB14416.2 .
    PIRi B69632.
    RefSeqi NP_390365.2. NC_000964.3.

    3D structure databases

    ProteinModelPortali P54495.
    SMRi P54495. Positions 3-315.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224308.BSU24850.

    Proteomic databases

    PaxDbi P54495.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB14416 ; CAB14416 ; BSU24850 .
    GeneIDi 938206.
    KEGGi bsu:BSU24850.
    PATRICi 18976806. VBIBacSub10457_2592.

    Organism-specific databases

    GenoListi BSU24850. [Micado ]

    Phylogenomic databases

    eggNOGi COG1940.
    HOGENOMi HOG000150087.
    KOi K00845.
    OrthoDBi EOG6CGCDC.
    PhylomeDBi P54495.

    Enzyme and pathway databases

    BioCyci BSUB:BSU24850-MONOMER.
    MetaCyc:MONOMER-5981.
    BRENDAi 2.7.1.2. 700.

    Family and domain databases

    InterProi IPR000600. ROK.
    IPR004654. ROK_glcA.
    [Graphical view ]
    Pfami PF00480. ROK. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00744. ROK_glcA_fam. 1 hit.
    PROSITEi PS01125. ROK. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Systematic sequencing of the 283 kb 210 degrees-232 degrees region of the Bacillus subtilis genome containing the skin element and many sporulation genes."
      Mizuno M., Masuda S., Takemaru K., Hosono S., Sato T., Takeuchi M., Kobayashi Y.
      Microbiology 142:3103-3111(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 168 / JH642.
    2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
      Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
      , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
      Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 168.
    3. "From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
      Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
      Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION TO 152 AND 198.
    4. "The glucose kinase of Bacillus subtilis."
      Skarlatos P., Dahl M.K.
      J. Bacteriol. 180:3222-3226(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: CHARACTERIZATION.

    Entry informationi

    Entry nameiGLK_BACSU
    AccessioniPrimary (citable) accession number: P54495
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: July 7, 2009
    Last modified: October 1, 2014
    This is version 90 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Bacillus subtilis
      Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3