P54427 (YBXI_BACSU) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 91.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable beta-lactamase YbxI EC=3.5.2.6 | ||||||
| Gene names |
| ||||||
| Organism | Bacillus subtilis (strain 168) [Reference proteome] [HAMAP] | ||||||
| Taxonomic identifier | 224308 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›  |
Protein attributes
| Sequence length | 267 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | A beta-lactam + H2O = a substituted beta-amino acid. |
| Sequence similarities | Belongs to the class-D beta-lactamase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Antibiotic resistance |
| Domain | Signal |
| Molecular function | Hydrolase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | antibiotic catabolic process Inferred from electronic annotation. Source: InterPro peptidoglycan-based cell wall biogenesisInferred from electronic annotation. Source: InterPro response to antibioticInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular_function | beta-lactamase activity Inferred from electronic annotation. Source: EC penicillin bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 23 | 23 | Potential | ||||||
| Chain | 24 – 267 | 244 | Probable beta-lactamase YbxI | PRO_0000017049 | |||||
Regions | |||||||||
| Region | 214 – 216 | 3 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Active site | 76 | 1 | Acyl-ester intermediate By similarity | ||||||
Amino acid modifications | |||||||||
| Modified residue | 79 | 1 | N6-carboxylysine By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 129 – 137 | 9 | YQALARDIG → IISISERYR Ref.3 | ||||||
| Sequence conflict | 169 | 1 | T → A in CAA63445. Ref.3 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Sequence analysis of the 70kb region between 17 and 23 degree of the Bacillus subtilis chromosome." Haga K., Liu H., Yasumoto K., Takahashi H., Yoshikawa H. Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168. |
| [2] | "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.  Danchin A.Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168. |
| [3] | "Characterization of csgA, a new member of the forespore-expressed sigmaG-regulon from Bacillus subtilis." Shcheptov M., Chyu G., Bagyan I., Cutting S.M. Gene 184:133-140(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 129-267. Strain: 168 / PY79. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AB006424 Genomic DNA. Translation: BAA33106.1. AL009126 Genomic DNA. Translation: CAB12003.1. X92859 Genomic DNA. Translation: CAA63445.1. |
| PIR | B69752. |
| RefSeq | NP_388091.1. NC_000964.3. |
3D structure databases | |
| ProteinModelPortal | P54427. |
| SMR | P54427. Positions 17-266. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 224308.BSU02090. |
Proteomic databases | |
| PaxDb | P54427. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | CAB12003; CAB12003; BSU02090. |
| GeneID | 938466. |
| KEGG | bsu:BSU02090. |
| PATRIC | 18971963. VBIBacSub10457_0210. |
Organism-specific databases | |
| GenoList | BSU02090. |
Phylogenomic databases | |
| eggNOG | COG2602. |
| HOGENOM | HOG000296772. |
| KO | K01467. |
| OMA | LYAKTGW. |
| ProtClustDB | CLSK886603. |
Enzyme and pathway databases | |
| BioCyc | BSUB:BSU02090-MONOMER. |
Family and domain databases | |
| Gene3D | 3.40.710.10. 1 hit. |
| InterPro | IPR012338. Beta-lactam/transpept-like. IPR002137. Beta-lactam_class-D_AS. IPR001460. PCN-bd_Tpept. [Graphical view] |
| Pfam | PF00905. Transpeptidase. 1 hit. [Graphical view] |
| SUPFAM | SSF56601. PBP_transp_fold. 1 hit. |
| PROSITE | PS00337. BETA_LACTAMASE_D. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | YBXI_BACSU | ||||||||
| Accession | Primary (citable) accession number: P54427 Secondary accession number(s): O31439 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Bacillus subtilis Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList |
| SIMILARITY comments Index of protein domains and families |