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P54277

- PMS1_HUMAN

UniProt

P54277 - PMS1_HUMAN

Protein

PMS1 protein homolog 1

Gene

PMS1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 145 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Probably involved in the repair of mismatches in DNA.1 Publication

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi571 – 63969HMG boxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ATPase activity Source: RefGenome
    2. ATP binding Source: InterPro
    3. DNA binding Source: ProtInc
    4. mismatched DNA binding Source: InterPro
    5. single-stranded DNA binding Source: RefGenome

    GO - Biological processi

    1. ATP catabolic process Source: GOC
    2. mismatch repair Source: RefGenome
    3. response to drug Source: Ensembl

    Keywords - Biological processi

    DNA damage, DNA repair

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    PMS1 protein homolog 1
    Alternative name(s):
    DNA mismatch repair protein PMS1
    Gene namesi
    Name:PMS1
    Synonyms:PMSL1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:9121. PMS1.

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. MutLalpha complex Source: RefGenome
    2. nucleus Source: ProtInc

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Keywords - Diseasei

    Hereditary nonpolyposis colorectal cancer, Tumor suppressor

    Organism-specific databases

    Orphaneti144. Hereditary nonpolyposis colon cancer.
    PharmGKBiPA33447.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 932932PMS1 protein homolog 1PRO_0000178004Add
    BLAST

    Proteomic databases

    MaxQBiP54277.
    PaxDbiP54277.
    PRIDEiP54277.

    PTM databases

    PhosphoSiteiP54277.

    Expressioni

    Gene expression databases

    ArrayExpressiP54277.
    BgeeiP54277.
    CleanExiHS_PMS1.
    GenevestigatoriP54277.

    Organism-specific databases

    HPAiCAB010233.
    HPA046075.

    Interactioni

    Subunit structurei

    The MutL-beta complex is a heterodimer of PMS1 and MLH1.1 Publication

    Protein-protein interaction databases

    BioGridi111391. 50 interactions.
    IntActiP54277. 1 interaction.
    STRINGi9606.ENSP00000406490.

    Structurei

    Secondary structure

    1
    932
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi577 – 59216
    Helixi598 – 61013
    Helixi614 – 62512
    Turni626 – 6283
    Helixi629 – 63810

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2CS1NMR-A571-649[»]
    ProteinModelPortaliP54277.
    SMRiP54277. Positions 16-330, 571-649.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP54277.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 HMG box DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0323.
    HOGENOMiHOG000039972.
    HOVERGENiHBG031886.
    InParanoidiP54277.
    KOiK10864.
    OMAiPFFHHLT.
    OrthoDBiEOG7S4X59.
    PhylomeDBiP54277.
    TreeFamiTF300711.

    Family and domain databases

    Gene3Di1.10.30.10. 1 hit.
    3.30.230.10. 1 hit.
    3.30.565.10. 1 hit.
    InterProiIPR013507. DNA_mismatch_repair_C.
    IPR014762. DNA_mismatch_repair_CS.
    IPR002099. DNA_mismatch_repair_fam.
    IPR003594. HATPase_ATP-bd.
    IPR009071. HMG_box_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    [Graphical view]
    PfamiPF01119. DNA_mis_repair. 1 hit.
    PF02518. HATPase_c. 1 hit.
    PF00505. HMG_box. 1 hit.
    [Graphical view]
    SMARTiSM00387. HATPase_c. 1 hit.
    SM00398. HMG. 1 hit.
    [Graphical view]
    SUPFAMiSSF47095. SSF47095. 1 hit.
    SSF54211. SSF54211. 1 hit.
    SSF55874. SSF55874. 1 hit.
    TIGRFAMsiTIGR00585. mutl. 1 hit.
    PROSITEiPS00058. DNA_MISMATCH_REPAIR_1. 1 hit.
    PS50118. HMG_BOX_2. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P54277-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MKQLPAATVR LLSSSQIITS VVSVVKELIE NSLDAGATSV DVKLENYGFD    50
    KIEVRDNGEG IKAVDAPVMA MKYYTSKINS HEDLENLTTY GFRGEALGSI 100
    CCIAEVLITT RTAADNFSTQ YVLDGSGHIL SQKPSHLGQG TTVTALRLFK 150
    NLPVRKQFYS TAKKCKDEIK KIQDLLMSFG ILKPDLRIVF VHNKAVIWQK 200
    SRVSDHKMAL MSVLGTAVMN NMESFQYHSE ESQIYLSGFL PKCDADHSFT 250
    SLSTPERSFI FINSRPVHQK DILKLIRHHY NLKCLKESTR LYPVFFLKID 300
    VPTADVDVNL TPDKSQVLLQ NKESVLIALE NLMTTCYGPL PSTNSYENNK 350
    TDVSAADIVL SKTAETDVLF NKVESSGKNY SNVDTSVIPF QNDMHNDESG 400
    KNTDDCLNHQ ISIGDFGYGH CSSEISNIDK NTKNAFQDIS MSNVSWENSQ 450
    TEYSKTCFIS SVKHTQSENG NKDHIDESGE NEEEAGLENS SEISADEWSR 500
    GNILKNSVGE NIEPVKILVP EKSLPCKVSN NNYPIPEQMN LNEDSCNKKS 550
    NVIDNKSGKV TAYDLLSNRV IKKPMSASAL FVQDHRPQFL IENPKTSLED 600
    ATLQIEELWK TLSEEEKLKY EEKATKDLER YNSQMKRAIE QESQMSLKDG 650
    RKKIKPTSAW NLAQKHKLKT SLSNQPKLDE LLQSQIEKRR SQNIKMVQIP 700
    FSMKNLKINF KKQNKVDLEE KDEPCLIHNL RFPDAWLMTS KTEVMLLNPY 750
    RVEEALLFKR LLENHKLPAE PLEKPIMLTE SLFNGSHYLD VLYKMTADDQ 800
    RYSGSTYLSD PRLTANGFKI KLIPGVSITE NYLEIEGMAN CLPFYGVADL 850
    KEILNAILNR NAKEVYECRP RKVISYLEGE AVRLSRQLPM YLSKEDIQDI 900
    IYRMKHQFGN EIKECVHGRP FFHHLTYLPE TT 932
    Length:932
    Mass (Da):105,830
    Last modified:October 1, 1996 - v1
    Checksum:iEC4F402937B616DF
    GO
    Isoform 2 (identifier: P54277-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         619-619: K → N
         620-781: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:770
    Mass (Da):86,643
    Checksum:i6C418989F9371A83
    GO
    Isoform 3 (identifier: P54277-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         195-233: Missing.

    Show »
    Length:893
    Mass (Da):101,377
    Checksum:iF017D1347739469E
    GO
    Isoform 4 (identifier: P54277-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-176: Missing.
         195-233: Missing.
         619-619: K → N
         620-781: Missing.

    Show »
    Length:555
    Mass (Da):62,919
    Checksum:i5FDD81AEB92618A6
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti27 – 271E → Q.1 Publication
    Corresponds to variant rs5742973 [ dbSNP | Ensembl ].
    VAR_019166
    Natural varianti202 – 2021R → K.1 Publication
    Corresponds to variant rs2066459 [ dbSNP | Ensembl ].
    VAR_014877
    Natural varianti394 – 3941M → T.1 Publication
    Corresponds to variant rs1145231 [ dbSNP | Ensembl ].
    VAR_012967
    Natural varianti501 – 5011G → R.2 Publications
    Corresponds to variant rs1145232 [ dbSNP | Ensembl ].
    VAR_012968
    Natural varianti632 – 6321N → S.1 Publication
    Corresponds to variant rs2066456 [ dbSNP | Ensembl ].
    VAR_014878
    Natural varianti720 – 7201E → D.1 Publication
    Corresponds to variant rs2066455 [ dbSNP | Ensembl ].
    VAR_014879
    Natural varianti793 – 7931Y → H.1 Publication
    Corresponds to variant rs1145234 [ dbSNP | Ensembl ].
    VAR_014880

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 176176Missing in isoform 4. 1 PublicationVSP_047692Add
    BLAST
    Alternative sequencei195 – 23339Missing in isoform 3 and isoform 4. 1 PublicationVSP_043371Add
    BLAST
    Alternative sequencei619 – 6191K → N in isoform 2 and isoform 4. 1 PublicationVSP_042676
    Alternative sequencei620 – 781162Missing in isoform 2 and isoform 4. 1 PublicationVSP_042677Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U13695 Genomic DNA. Translation: AAA63922.1.
    AB102870 mRNA. Translation: BAD89399.1.
    AB102872 mRNA. Translation: BAD89401.1.
    AB102875 mRNA. Translation: BAD89404.1.
    AY267352 Genomic DNA. Translation: AAO89079.1.
    AC008122 Genomic DNA. No translation available.
    AC013468 Genomic DNA. No translation available.
    CH471058 Genomic DNA. Translation: EAX10883.1.
    CH471058 Genomic DNA. Translation: EAX10885.1.
    BC096330 mRNA. Translation: AAH96330.1.
    BC096332 mRNA. Translation: AAH96332.1.
    CCDSiCCDS2302.1. [P54277-1]
    CCDS46473.1. [P54277-2]
    CCDS46474.1. [P54277-3]
    PIRiS47597.
    RefSeqiNP_000525.1. NM_000534.4. [P54277-1]
    NP_001121615.1. NM_001128143.1. [P54277-3]
    NP_001121616.1. NM_001128144.1. [P54277-2]
    NP_001276337.1. NM_001289408.1.
    XP_005246704.1. XM_005246647.1. [P54277-1]
    UniGeneiHs.111749.

    Genome annotation databases

    EnsembliENST00000409593; ENSP00000387169; ENSG00000064933. [P54277-4]
    ENST00000409823; ENSP00000387125; ENSG00000064933. [P54277-3]
    ENST00000441310; ENSP00000406490; ENSG00000064933. [P54277-1]
    ENST00000447232; ENSP00000401064; ENSG00000064933. [P54277-2]
    GeneIDi5378.
    KEGGihsa:5378.
    UCSCiuc002urh.4. human. [P54277-1]
    uc002uri.4. human. [P54277-2]
    uc002urk.4. human. [P54277-3]

    Polymorphism databases

    DMDMi1709683.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Web resourcesi

    Atlas of Genetics and Cytogenetics in Oncology and Haematology
    Hereditary non-polyposis colorectal cancer db
    NIEHS-SNPs

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U13695 Genomic DNA. Translation: AAA63922.1 .
    AB102870 mRNA. Translation: BAD89399.1 .
    AB102872 mRNA. Translation: BAD89401.1 .
    AB102875 mRNA. Translation: BAD89404.1 .
    AY267352 Genomic DNA. Translation: AAO89079.1 .
    AC008122 Genomic DNA. No translation available.
    AC013468 Genomic DNA. No translation available.
    CH471058 Genomic DNA. Translation: EAX10883.1 .
    CH471058 Genomic DNA. Translation: EAX10885.1 .
    BC096330 mRNA. Translation: AAH96330.1 .
    BC096332 mRNA. Translation: AAH96332.1 .
    CCDSi CCDS2302.1. [P54277-1 ]
    CCDS46473.1. [P54277-2 ]
    CCDS46474.1. [P54277-3 ]
    PIRi S47597.
    RefSeqi NP_000525.1. NM_000534.4. [P54277-1 ]
    NP_001121615.1. NM_001128143.1. [P54277-3 ]
    NP_001121616.1. NM_001128144.1. [P54277-2 ]
    NP_001276337.1. NM_001289408.1.
    XP_005246704.1. XM_005246647.1. [P54277-1 ]
    UniGenei Hs.111749.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2CS1 NMR - A 571-649 [» ]
    ProteinModelPortali P54277.
    SMRi P54277. Positions 16-330, 571-649.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 111391. 50 interactions.
    IntActi P54277. 1 interaction.
    STRINGi 9606.ENSP00000406490.

    PTM databases

    PhosphoSitei P54277.

    Polymorphism databases

    DMDMi 1709683.

    Proteomic databases

    MaxQBi P54277.
    PaxDbi P54277.
    PRIDEi P54277.

    Protocols and materials databases

    DNASUi 5378.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000409593 ; ENSP00000387169 ; ENSG00000064933 . [P54277-4 ]
    ENST00000409823 ; ENSP00000387125 ; ENSG00000064933 . [P54277-3 ]
    ENST00000441310 ; ENSP00000406490 ; ENSG00000064933 . [P54277-1 ]
    ENST00000447232 ; ENSP00000401064 ; ENSG00000064933 . [P54277-2 ]
    GeneIDi 5378.
    KEGGi hsa:5378.
    UCSCi uc002urh.4. human. [P54277-1 ]
    uc002uri.4. human. [P54277-2 ]
    uc002urk.4. human. [P54277-3 ]

    Organism-specific databases

    CTDi 5378.
    GeneCardsi GC02P190648.
    GeneReviewsi PMS1.
    H-InvDB HIX0029784.
    HGNCi HGNC:9121. PMS1.
    HPAi CAB010233.
    HPA046075.
    MIMi 600258. gene.
    neXtProti NX_P54277.
    Orphaneti 144. Hereditary nonpolyposis colon cancer.
    PharmGKBi PA33447.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0323.
    HOGENOMi HOG000039972.
    HOVERGENi HBG031886.
    InParanoidi P54277.
    KOi K10864.
    OMAi PFFHHLT.
    OrthoDBi EOG7S4X59.
    PhylomeDBi P54277.
    TreeFami TF300711.

    Miscellaneous databases

    ChiTaRSi PMS1. human.
    EvolutionaryTracei P54277.
    GeneWikii PMS1.
    GenomeRNAii 5378.
    NextBioi 20866.
    PROi P54277.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P54277.
    Bgeei P54277.
    CleanExi HS_PMS1.
    Genevestigatori P54277.

    Family and domain databases

    Gene3Di 1.10.30.10. 1 hit.
    3.30.230.10. 1 hit.
    3.30.565.10. 1 hit.
    InterProi IPR013507. DNA_mismatch_repair_C.
    IPR014762. DNA_mismatch_repair_CS.
    IPR002099. DNA_mismatch_repair_fam.
    IPR003594. HATPase_ATP-bd.
    IPR009071. HMG_box_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    [Graphical view ]
    Pfami PF01119. DNA_mis_repair. 1 hit.
    PF02518. HATPase_c. 1 hit.
    PF00505. HMG_box. 1 hit.
    [Graphical view ]
    SMARTi SM00387. HATPase_c. 1 hit.
    SM00398. HMG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47095. SSF47095. 1 hit.
    SSF54211. SSF54211. 1 hit.
    SSF55874. SSF55874. 1 hit.
    TIGRFAMsi TIGR00585. mutl. 1 hit.
    PROSITEi PS00058. DNA_MISMATCH_REPAIR_1. 1 hit.
    PS50118. HMG_BOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Tissue: Gall bladder.
    2. "PMS1 mRNA, nirs splice variants."
      Hayashi A., Sameshima E., Tabata Y., Iida K., Mitsuyama M., Kanai S., Furuya T., Saito T.
      Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3 AND 4).
    3. NIEHS SNPs program
      Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS GLN-27; LYS-202; ARG-501; SER-632; ASP-720 AND HIS-793.
    4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-920 (ISOFORM 1).
    7. "Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells."
      Leung W.K., Kim J.J., Wu L., Sepulveda J.L., Sepulveda A.R.
      J. Biol. Chem. 275:15728-15732(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBUNIT, INTERACTION WITH MLH1.
    8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    10. "Solution structure of the HMG domain of human DNA mismatch repair protein."
      RIKEN structural genomics initiative (RSGI)
      Submitted (NOV-2005) to the PDB data bank
      Cited for: STRUCTURE BY NMR OF 571-649.
    11. "Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer."
      Wang Q., Lasset C., Desseigne F., Saurin J.-C., Maugard C., Navarro C., Ruano E., Descos L., Trillet-Lenoir V., Bosset J.-F., Puisieux A.
      Hum. Genet. 105:79-85(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: VARIANTS THR-394 AND ARG-501.

    Entry informationi

    Entry nameiPMS1_HUMAN
    AccessioniPrimary (citable) accession number: P54277
    Secondary accession number(s): D3DPI1
    , Q4VAL4, Q5FBZ3, Q5FBZ6, Q5FBZ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 145 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3