P54238 (G6PI1_CLARO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate isomerase, cytosolic 1
Short name=GPI
EC=5.3.1.9

Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI

Gene names

Name:

PGIC1

Organism

Clarkia rostrata

Taxonomic identifier

49041 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Myrtales › Onagraceae › Clarkia

Protein attributes

Sequence length	570 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate.
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 570	570	Glucose-6-phosphate isomerase, cytosolic 1		PRO_0000180557
Sites
	Active site	360	1	Proton donor By similarity
	Active site	391	1	By similarity
	Active site	516	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P54238 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 262F78005F2CD820	FASTA	570	62,875
	10 20 30 40 50 60 MASPALISET EAWKDLKAHL EGIKMTHLRE LMGDTERCQS MMVEFDNIFL DYSRQQASPD 70 80 90 100 110 120 TISKLYKLAD EAHLKQKIDR MYNGDHINTT ENRSVLHVAL RAPRNSAICS DGKNVVPDVW 130 140 150 160 170 180 SVLDKIKDFS DRVRNGSWIG ATGKELKDVI AVGIGGSFLG PLFVHTALQT DPEASKNARG 190 200 210 220 230 240 RELRFLANVD PIDVARNISG LNPETTLVVV VSKTFTTAET MLNARTLREW ISSALGPSAV 250 260 270 280 290 300 AKHMVAVSTN LPLVEKFGID PNNAFAFWDW VGGRYSVCSA VGVLPLSLQY GFAVVEKFLQ 310 320 330 340 350 360 GAHSIDQHFS SAPFEKNIPV LLGLLSVWNV SFLGYPARAI LPYSQALEKL APHIQQVSME 370 380 390 400 410 420 SNGKGVSVDG LPLPFESGEI DFGEPGTNGQ HSFYQLIHQG RVIPCDFIGV VKSQQPVYLK 430 440 450 460 470 480 GEVVNNHDEL MSNFFAQPDA LAYGKTPEEL KKENVSEHLI PHKTFTGNRP SISILLPTLD 490 500 510 520 530 540 AYRIGQVLAI YEHRVAVQGF VWGINSFDQW GVELGKSLAT QVRKQLHGSR VKGEPVEEGF 550 560 570 NFSTKTLLTR YLQATSDVPA DPSTLLPNII

References

[1]	"Phylogenetic relationships among the sections of Clarkia (Onagraceae) inferred from the nucleotide sequences of PgiC." Gottlieb L.D., Ford V.S. Syst. Bot. 21:1-18(1996) [Agricola: IND20535960] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Population LDG 8810.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X89392 Genomic DNA. Translation: CAA61572.1.
3D structure databases
ProteinModelPortal	P54238.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001672. G6P_Isomerase. IPR023096. G6P_Isomerase_C. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
Gene3D	G3DSA:1.10.1390.10. G6P_Isomerase_C. 1 hit.
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI1_CLARO

Accession

Primary (citable) accession number: P54238

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	September 21, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program