Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase, cytosolic 1

Gene

PGIC1

Organism
Clarkia mildrediae
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase, cytosolic 1 (PGIC1), Glucose-6-phosphate isomerase (PgiC1)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei360Proton donorBy similarity1
Active sitei391By similarity1
Active sitei516By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase, cytosolic 1 (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:PGIC1
OrganismiClarkia mildrediae
Taxonomic identifieri49756 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsMyrtalesOnagraceaeOnagroideaeOnagreaeClarkia

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001805561 – 568Glucose-6-phosphate isomerase, cytosolic 1Add BLAST568

Proteomic databases

PRIDEiP54237

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP54237
SMRiP54237
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

P54237-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASPALISET EAWKDLKAHL EGIKRTHLRE LMGDTERCQS MMVEFDNIFL
60 70 80 90 100
DYSRQQAIPD TIKKLYKLAD AAHLKQKIDR MYNGDHINST ENRSVLHVAL
110 120 130 140 150
RAPRDSAICS DGKNVVPDVW NVLDKIKDFS DRVRNGSWIG ATGKELKDVI
160 170 180 190 200
AVGIGGSFLG PLFVHTALQT DPEASKNARG RELRFLANVD PIDVARNISG
210 220 230 240 250
LNPETTLVVV VSKTFTTAET MLNARTLREW ISSALGPTAV AKHMVAVSTN
260 270 280 290 300
IPLVEKFGID PNNAFAFWDW VGGRYSVCSA VGVLPLSLQY GFAVVEKFLQ
310 320 330 340 350
GAHSIDQHFS SAPFEKNIPV LLGLLSVWNV SFLGYPARAI LPYSQALEKL
360 370 380 390 400
APHIQQVSME SNGKGVSIDG LPLPFESGEI DFGEPGTNGQ HSFYQLIHQG
410 420 430 440 450
RVIPCDFIGV VKSQQPVYLK GEVVNNHDEL MSNFFAQPDA LAYGKTPEQL
460 470 480 490 500
KNENVAEHLI PHKTFTGNRP SLSILLPTLD AYRIGQLLAI YEHRVAVQGF
510 520 530 540 550
VWGINSFDQW GVELGKSLAT QVRKQLHGSR VKGEPVEGFN FSTKTLLTKY
560
LEATSDVPAD PSTLLPNI
Length:568
Mass (Da):62,665
Last modified:October 1, 1996 - v1
Checksum:iEF487A59D734EB8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X89389 Genomic DNA Translation: CAA61569.1

Similar proteinsi

Entry informationi

Entry nameiG6PI1_CLAMI
AccessioniPrimary (citable) accession number: P54237
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health