P54222 (BETB1_RHIME) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 87.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Betaine aldehyde dehydrogenase 1 Short name=BADH 1 EC=1.2.1.8 | ||||||||
| Gene names |
| ||||||||
| Organism | Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP] | ||||||||
| Taxonomic identifier | 266834 [NCBI] | ||||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › ![]() |
Protein attributes
| Sequence length | 487 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Catalytic activity | Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP-Rule MF_00804 |
| Pathway | Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP-Rule MF_00804 |
| Sequence similarities | Belongs to the aldehyde dehydrogenase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: HAMAP |
| Molecular_function | betaine-aldehyde dehydrogenase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 487 | 487 | Betaine aldehyde dehydrogenase 1 HAMAP-Rule MF_00804 | PRO_0000056553 | |||||
Regions | |||||||||
| Nucleotide binding | 228 – 233 | 6 | NAD By similarity | ||||||
Sites | |||||||||
| Active site | 250 | 1 | By similarity | ||||||
| Active site | 284 | 1 | By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 82 | 1 | R → L in AAC13368. Ref.1 | ||||||
| Sequence conflict | 374 | 1 | V → D in AAC13368. Ref.1 | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U39940 Genomic DNA. Translation: AAC13368.1. AL591688 Genomic DNA. Translation: CAC45520.1. |
| RefSeq | NP_385054.1. NC_003047.1. |
3D structure databases | |
| ProteinModelPortal | P54222. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 266834.SMc00094. |
Proteomic databases | |
| ProMEX | P54222. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | CAC45520; CAC45520; SMc00094. |
| GeneID | 1232591. |
| KEGG | sme:SMc00094. |
| PATRIC | 23631171. VBISinMel96828_2347. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG1012. |
| HOGENOM | HOG000271505. |
| KO | K00130. |
| OMA | MCVLDFE. |
| ProtClustDB | PRK13252. |
Enzyme and pathway databases | |
| BioCyc | MetaCyc:MONOMER-246. SMEL266834:GJF6-971-MONOMER. |
| UniPathway | UPA00529; UER00386. |
Family and domain databases | |
| Gene3D | 3.40.309.10. 1 hit. 3.40.605.10. 1 hit. |
| HAMAP | MF_00804. BADH. |
| InterPro | IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR011264. Betaine_Ald_DH. [Graphical view] |
| Pfam | PF00171. Aldedh. 1 hit. [Graphical view] |
| SUPFAM | SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit. |
| TIGRFAMs | TIGR01804. BADH. 1 hit. |
| PROSITE | PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BETB1_RHIME | ||||||||
| Accession | Primary (citable) accession number: P54222 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with
