P54209 (ATC1_DUNBI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cation-transporting ATPase CA1
EC=3.6.3.-

Gene names

Name:

CA1

Organism

Dunaliella bioculata (Green alga)

Taxonomic identifier

13790 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Chlorophyta › Chlorophyceae › Chlamydomonadales › Dunaliellaceae › Dunaliella

Protein attributes

Sequence length	1037 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Could possibly be a calcium ATPase.
Catalytic activity	ATP + H2O = ADP + phosphate.
Subcellular location	Membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. [View classification]

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Magnesium Nucleotide-binding
Molecular function	Hydrolase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW calcium-transporting ATPase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1037	1037	Cation-transporting ATPase CA1		PRO_0000046241
Regions
	Transmembrane	83 – 103	21	Helical; Potential
	Transmembrane	109 – 129	21	Helical; Potential
	Transmembrane	276 – 296	21	Helical; Potential
	Transmembrane	317 – 337	21	Helical; Potential
	Transmembrane	398 – 418	21	Helical; Potential
	Transmembrane	731 – 751	21	Helical; Potential
	Transmembrane	790 – 810	21	Helical; Potential
	Transmembrane	852 – 872	21	Helical; Potential
	Transmembrane	945 – 965	21	Helical; Potential
	Transmembrane	971 – 991	21	Helical; Potential
Sites
	Active site	370	1	4-aspartylphosphate intermediate Probable

Sequences

	Sequence		Length	Mass (Da)
	P54209 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 18100AC444F1EA87	FASTA	1,037	111,801
	10 20 30 40 50 60 MVSHASSGRP SSRDTGMVYL GLGMQDAYSS EVQEVAAFYH VDLDRGLSDR DVQQARIKYG 70 80 90 100 110 120 RNQMEAEQST PLWKLILKQF DDLLVKILLG AAIVDFIIAI SEGESIQSGL IEPMVILLIL 130 140 150 160 170 180 VANATVGVVT ERNAEKAIEQ LKSYEADDAT VLRNGQLQLI PSADIVPGDI VELAVGNKVP 190 200 210 220 230 240 ADTRVSHIYT TSLKIDQSLL TGESQAVEKH TEVVHNEQAV YQDKLNMLFS GTLVVAGRAR 250 260 270 280 290 300 GIVVGTGSNT AIGKIRDAMG VEEDVVTPLK AKLDEFGALL SKVIAGICVL VWVVNINRFN 310 320 330 340 350 360 DPALGGWFQG AIHYFKIAVA LAVAAIPEGL PAVVTTCLAL GTRKMARHNA IVRTLPSVET 370 380 390 400 410 420 LGCTTVICSD KTGTLTTNQM SVIKVAAVQS SSSQLAEFDV TGTTFSPEGM VLGPGGVVLR 430 440 450 460 470 480 QPADTPCLAH AAQCAALCND SQVFVAQKTG TLQRIGESTE IALRVFAEKI GLPSSIRPDR 490 500 510 520 530 540 PISRSQFGTN NFWQEDVERL ALLEFSRDRK MMSVLVKGSD RQHNIWSKGA PEFVLRKCSH 550 560 570 580 590 600 VLANNGEGAV PLTDNMRQAI LSDMQAFGSR QALRCLALAF KSVPTTTTKL DYSDESGLTF 610 620 630 640 650 660 IGLLGMHDPP RPECRSALST CHNAGIKVIM VTGDNKGTAE AVARQVGALS PSTALAGSDD 670 680 690 700 710 720 EDNLGISYTG REFEEMGALG QAAATRNLVV LSRVEPMHKL RLVELLKAQG HVVAMTGDGV 730 740 750 760 770 780 NDAPALLRAD IGIAMGSGTA VAKHAADMVL GDDNFATIVF AVAEGRVIFN NTKQFIRYMI 790 800 810 820 830 840 SSNIGEVVAI FLAALLGLPE VLTPVQLLWV NLVTDGLPAT ALGFNRADKD MMARGPRRVD 850 860 870 880 890 900 DPIVNGWLFL RYLIIGMYVG IVTVYGFIWW YISFPEGGNM TWSQLTHFQA CASQPGGAKD 910 920 930 940 950 960 CEVFHSKHPT TISMSVLVVV EMFNALNNLS EDSSLLRIPP WDNKWLVGAI ATSMALHFGI 970 980 990 1000 1010 1020 LYTGASAMFG VTGLSFAEWT MVIKLSAPVI LVDEIMKAWS RRRQRHPASS RGGPVSLMEI 1030 QVPLTSSSRD EAALKLK

References

[1]	"Molecular cloning of a P-type Ca(2+)-ATPase from the halotolerant alga Dunaliella bioculata." Raschke B.C., Wolf A.H. Planta 200:78-84(1996) [PubMed: 8987619] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: SAG 19-4.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X93592 mRNA. Translation: CAA63790.1.
3D structure databases
ProteinModelPortal	P54209.
SMR	P54209. Positions 24-1003.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR005782. ATPase_P-typ_Ca-transp. IPR006068. ATPase_P-typ_cation-transptr_C. IPR004014. ATPase_P-typ_cation-transptr_N. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR000695. ATPase_P-typ_H-transp. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR023298. ATPase_P-typ_TM_dom. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit. G3DSA:1.20.1110.10. ATPase_P-typ_TM_dom. 2 hits.
Pfam	PF00689. Cation_ATPase_C. 1 hit. PF00690. Cation_ATPase_N. 1 hit. PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE. PR00120. HATPASE.
SMART	SM00831. Cation_ATPase_N. 1 hit. [Graphical view]
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01116. ATPase-IIA1_Ca. 1 hit. TIGR01494. ATPase_P-type. 3 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATC1_DUNBI

Accession

Primary (citable) accession number: P54209

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	June 28, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program