Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peptide methionine sulfoxide reductase MsrB

Gene

msrB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei115NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciBSUB:BSU21680-MONOMER.
BRENDAi1.8.4.12. 658.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide methionine sulfoxide reductase MsrBUniRule annotation (EC:1.8.4.12UniRule annotation)
Alternative name(s):
Peptide-methionine (R)-S-oxide reductaseUniRule annotation
Gene namesi
Name:msrBUniRule annotation
Synonyms:yppQ
Ordered Locus Names:BSU21680
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001402621 – 143Peptide methionine sulfoxide reductase MsrBAdd BLAST143

Proteomic databases

PaxDbiP54155.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100011941.

Structurei

Secondary structure

1143
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi2 – 11Combined sources10
Helixi14 – 22Combined sources9
Turni32 – 34Combined sources3
Beta strandi39 – 44Combined sources6
Turni45 – 47Combined sources3
Beta strandi50 – 53Combined sources4
Turni54 – 56Combined sources3
Beta strandi60 – 64Combined sources5
Beta strandi66 – 68Combined sources3
Turni72 – 74Combined sources3
Beta strandi75 – 80Combined sources6
Beta strandi87 – 92Combined sources6
Turni93 – 95Combined sources3
Beta strandi98 – 104Combined sources7
Beta strandi108 – 111Combined sources4
Beta strandi113 – 116Combined sources4
Helixi118 – 120Combined sources3
Beta strandi121 – 125Combined sources5
Helixi126 – 129Combined sources4
Turni130 – 133Combined sources4
Helixi135 – 140Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2KZNNMR-A1-143[»]
3E0OX-ray2.60A/B/C/D/E/F1-143[»]
ProteinModelPortaliP54155.
SMRiP54155.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP54155.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 126MsrBPROSITE-ProRule annotationAdd BLAST122

Sequence similaritiesi

Belongs to the MsrB Met sulfoxide reductase family.UniRule annotation
Contains 1 MsrB (methionine-R-sulfoxide reductase) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105E0X. Bacteria.
COG0229. LUCA.
HOGENOMiHOG000243425.
InParanoidiP54155.
KOiK07305.
OMAiRMQYEVT.
PhylomeDBiP54155.

Family and domain databases

Gene3Di2.170.150.20. 1 hit.
HAMAPiMF_01400. MsrB. 1 hit.
InterProiIPR028427. Met_Sox_Rdtase.
IPR002579. Met_Sox_Rdtase_MsrB.
IPR011057. Mss4-like.
[Graphical view]
PANTHERiPTHR10173. PTHR10173. 1 hit.
PfamiPF01641. SelR. 1 hit.
[Graphical view]
SUPFAMiSSF51316. SSF51316. 1 hit.
TIGRFAMsiTIGR00357. TIGR00357. 1 hit.
PROSITEiPS51790. MSRB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P54155-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYNKEEKIK SLNRMQYEVT QNNGTEPPFQ NEYWDHKEEG LYVDIVSGKP
60 70 80 90 100
LFTSKDKFDS QCGWPSFTKP IEEEVEEKLD TSHGMIRTEV RSRTADSHLG
110 120 130 140
HVFNDGPGPN GLRYCINSAA LRFVPKHKLK EEGYESYLHL FNK
Length:143
Mass (Da):16,602
Last modified:October 1, 1996 - v1
Checksum:iEC29C9B017C68EED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77246 Genomic DNA. Translation: AAA96648.1.
AL009126 Genomic DNA. Translation: CAB14086.1.
PIRiF69940.
RefSeqiNP_390051.1. NC_000964.3.
WP_003230813.1. NZ_JNCM01000036.1.

Genome annotation databases

EnsemblBacteriaiCAB14086; CAB14086; BSU21680.
GeneIDi939102.
KEGGibsu:BSU21680.
PATRICi18976141. VBIBacSub10457_2261.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77246 Genomic DNA. Translation: AAA96648.1.
AL009126 Genomic DNA. Translation: CAB14086.1.
PIRiF69940.
RefSeqiNP_390051.1. NC_000964.3.
WP_003230813.1. NZ_JNCM01000036.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2KZNNMR-A1-143[»]
3E0OX-ray2.60A/B/C/D/E/F1-143[»]
ProteinModelPortaliP54155.
SMRiP54155.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100011941.

Proteomic databases

PaxDbiP54155.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14086; CAB14086; BSU21680.
GeneIDi939102.
KEGGibsu:BSU21680.
PATRICi18976141. VBIBacSub10457_2261.

Phylogenomic databases

eggNOGiENOG4105E0X. Bacteria.
COG0229. LUCA.
HOGENOMiHOG000243425.
InParanoidiP54155.
KOiK07305.
OMAiRMQYEVT.
PhylomeDBiP54155.

Enzyme and pathway databases

BioCyciBSUB:BSU21680-MONOMER.
BRENDAi1.8.4.12. 658.

Miscellaneous databases

EvolutionaryTraceiP54155.

Family and domain databases

Gene3Di2.170.150.20. 1 hit.
HAMAPiMF_01400. MsrB. 1 hit.
InterProiIPR028427. Met_Sox_Rdtase.
IPR002579. Met_Sox_Rdtase_MsrB.
IPR011057. Mss4-like.
[Graphical view]
PANTHERiPTHR10173. PTHR10173. 1 hit.
PfamiPF01641. SelR. 1 hit.
[Graphical view]
SUPFAMiSSF51316. SSF51316. 1 hit.
TIGRFAMsiTIGR00357. TIGR00357. 1 hit.
PROSITEiPS51790. MSRB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMSRB_BACSU
AccessioniPrimary (citable) accession number: P54155
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.