P54125 (PEPF_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Oligoendopeptidase F homolog
EC=3.4.24.-

Gene names

Name:	pepF
Ordered Locus Names:	MPN_197
ORF Names:	MP634

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma pneumoniae

Protein attributes

Sequence length	611 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 zinc ion By similarity.
Sequence similarities	Belongs to the peptidase M3B family.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Hydrolase Metalloprotease Protease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 611	611	Oligoendopeptidase F homolog		PRO_0000078168
Sites
	Active site	385	1	By similarity
	Metal binding	384	1	Zinc; catalytic By similarity
	Metal binding	388	1	Zinc; catalytic By similarity
	Metal binding	391	1	Zinc; catalytic By similarity

Sequences

	Sequence		Length	Mass (Da)
	P54125 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 8DB896D570BB215D	FASTA	611	70,959
	10 20 30 40 50 60 MNNQYNWNLE VLLNGKSLAD NFTELKQLSE QEKALYDGGA CFQTKAKFTE FLQLQEKIEV 70 80 90 100 110 120 LENRYSNFLS NKHAENSLDK TINDALFQYE MFKSEHALVF VDFEKNLFKH EKVIRAYLQD 130 140 150 160 170 180 PALKQYQRDF ELVWRNKKHQ IDPASQKLLA QISPAWNQAD KIFNVLSTAD LNLQPVVYKG 190 200 210 220 230 240 KTYVINAVSD YQSLLENKDR GLREAAYKVW LEIYWPTRNT LSVSLVENYI QLETFAKLKK 250 260 270 280 290 300 HPNYIAKTAF DDEIDVAFID FVYEQVASFA PTFKAFQSLR KQIYKHVLKL DKAQPWDLSV 310 320 330 340 350 360 PLFKASGDYT IEQAQTDALK ILAPMGSEYL EVVKEAFRER WISWLPDKNK YTGAYSISNV 370 380 390 400 410 420 KGLDHYFILM NFDKTRASLN TLVHELGHSV HSWYASKYQT QNLDPTIFYA EIASICNELL 430 440 450 460 470 480 LCYHDIINYE NRNPQQLIRS LMEQISHFFG ATTRQLMFSQ FEQDTLKLIQ QNQKPDFKTL 490 500 510 520 530 540 VEIYGKTAIK YQAANADAIT KKLKQTKYQK SLAYITSIPH FYAGNFYVYK YAIGQVVGTL 550 560 570 580 590 600 VGKKLSAGDS NMLAAYKRFL SSGSTLPPLE TIKLLGIDLT QPEPWQEAHA ELKRWIKLVQ 610 TAFKQLQHKK R

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of 56 kb from the genome of the bacterium Mycoplasma pneumoniae comprising the dnaA region, the atp operon and a cluster of ribosomal protein genes." Hilbert H., Himmelreich R., Plagens H., Herrmann R. Nucleic Acids Res. 24:628-639(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 29342 / M129.
[2]	"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U34795 Genomic DNA. Translation: AAC43684.1. U00089 Genomic DNA. Translation: AAB96282.1.
PIR	S62811.
RefSeq	NP_109885.1. NC_000912.1.
3D structure databases
ProteinModelPortal	P54125.
ModBase	Search...
Protein-protein interaction databases
STRING	272634.MPN197.
Protein family/group databases
MEROPS	M03.007.
Proteomic databases
PaxDb	P54125.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB96282; AAB96282; MPN_197.
GeneID	876899.
KEGG	mpn:MPN197.
PATRIC	20021717. VBIMycPne110_0215.
Phylogenomic databases
eggNOG	COG1164.
KO	K08602.
OMA	EVYENLF.
ProtClustDB	CLSK336933.
Enzyme and pathway databases
BioCyc	MPNE272634:GJ6Z-204-MONOMER.
Family and domain databases
InterPro	IPR001567. Pept_M3A_M3B. IPR004438. Peptidase_M3B. IPR013647. Peptidase_M3B_oligopepF_N. [Graphical view]
Pfam	PF01432. Peptidase_M3. 1 hit. PF08439. Peptidase_M3_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00181. pepF. 1 hit.
PROSITE	PS00142. ZINC_PROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PEPF_MYCPN

Accession

Primary (citable) accession number: P54125

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program