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P54123

- RNJ_SYNY3

UniProt

P54123 - RNJ_SYNY3

Protein

Ribonuclease J

Gene

rnj

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay By similarity.By similarity

    Cofactori

    Binds up to 2 Zn2+ ions per subunit. It is not clear if Zn2+ or Mg2+ is physiologically important.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi75 – 751Zinc 1; catalyticUniRule annotation
    Metal bindingi77 – 771Zinc 1; catalyticUniRule annotation
    Metal bindingi79 – 791Zinc 2; catalyticUniRule annotation
    Metal bindingi80 – 801Zinc 2; catalyticUniRule annotation
    Metal bindingi145 – 1451Zinc 1; catalyticUniRule annotation
    Metal bindingi167 – 1671Zinc 1; catalyticUniRule annotation
    Metal bindingi167 – 1671Zinc 2; catalyticUniRule annotation
    Metal bindingi394 – 3941Zinc 2; catalyticUniRule annotation

    GO - Molecular functioni

    1. endonuclease activity Source: UniProtKB-KW
    2. exonuclease activity Source: UniProtKB-KW
    3. metal ion binding Source: UniProtKB-KW
    4. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. rRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Exonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    rRNA processing

    Keywords - Ligandi

    Metal-binding, RNA-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease JUniRule annotation (EC:3.1.-.-UniRule annotation)
    Short name:
    RNase JUniRule annotation
    Gene namesi
    Name:rnjUniRule annotation
    Ordered Locus Names:slr0551
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 640640Ribonuclease JPRO_0000215273Add
    BLAST

    Proteomic databases

    PaxDbiP54123.

    Interactioni

    Subunit structurei

    Homodimer, may be a subunit of the RNA degradosome.UniRule annotation

    Protein-protein interaction databases

    IntActiP54123. 4 interactions.
    STRINGi1148.slr0551.

    Structurei

    3D structure databases

    ProteinModelPortaliP54123.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni368 – 3725Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0595.
    KOiK12574.
    OMAiKDEKHLI.
    OrthoDBiEOG6P5ZDC.
    PhylomeDBiP54123.

    Family and domain databases

    Gene3Di3.60.15.10. 1 hit.
    HAMAPiMF_01491. RNase_J_bact.
    InterProiIPR001279. Beta-lactamas-like.
    IPR011108. RMMBL.
    IPR004613. RNase_J.
    IPR001587. RNase_J_CS.
    [Graphical view]
    PANTHERiPTHR11203:SF22. PTHR11203:SF22. 1 hit.
    PfamiPF00753. Lactamase_B. 1 hit.
    PF07521. RMMBL. 1 hit.
    [Graphical view]
    PIRSFiPIRSF004803. RnjA. 1 hit.
    SMARTiSM00849. Lactamase_B. 1 hit.
    [Graphical view]
    SUPFAMiSSF56281. SSF56281. 1 hit.
    TIGRFAMsiTIGR00649. MG423. 1 hit.
    PROSITEiPS01292. UPF0036. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P54123-1 [UniParc]FASTAAdd to Basket

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    MAKNTQTQAL KILPLGGLHE IGKNTCVFEY DDEILLLDAG LAFPTDDMHG    50
    VNVVLPDMTY LRENREKIKG MVVTHGHEDH IGGIAYHLKQ FDIPIIYGPR 100
    LAMALLRDKL EEAGMLERTN LQTVSPREMV RLGKSFVVEF IRNTHSIADS 150
    YCLAIHTPLG VVMHSGDFKI DHTPIDGEFF DLQKVAEYGE KGVLCLLSDS 200
    TNAEVPGITP SEASVIPNLD RVFSQAEGRL MVTTFASSVH RVNIILSLAQ 250
    KHQRKVAVVG RSMLNVIAHA RKLGYIKCPD NLFVPLKAAR NLPDQQQLIL 300
    TTGSQGEPLA AMTRISNGEH PQIKIRQGDT VVFSANPIPG NTIAVVNTID 350
    RLMMQGANVI YGKHQGIHVS GHASQEEHKM LLALTRPKFF VPVHGEHRML 400
    VKHSQMAQAQ GIPSENIVIV NNGDVIELTG DRIRVAGQVP SGIELVDQAG 450
    IVHESTMAER QQMAEDGLVT VAAALSKTGT LLAYPEVHCR GVVMTIQPKL 500
    LEELIVRTIE NFLTERWSEF THGSNGSTEV SWNALQKELE SSLQRLIKRE 550
    LQSSPMVLLM LQTDTPIELD QVPQNVSTVS ATSATPAPRK KVVLTKTPEP 600
    KVKAKPEKKV VTTAEPSAQP VSTTKVYRRS RKRSTTSVSS 640
    Length:640
    Mass (Da):70,427
    Last modified:October 1, 1996 - v1
    Checksum:iF4D1CC23EA656E6D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA10871.1.
    PIRiS76024.
    RefSeqiNP_442800.1. NC_000911.1.
    YP_005652861.1. NC_017277.1.
    YP_007452676.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA10871; BAA10871; BAA10871.
    GeneIDi952079.
    KEGGisyn:slr0551.
    syy:SYNGTS_2908.
    syz:MYO_129360.
    PATRICi23843368. VBISynSp132158_3220.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA10871.1 .
    PIRi S76024.
    RefSeqi NP_442800.1. NC_000911.1.
    YP_005652861.1. NC_017277.1.
    YP_007452676.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P54123.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P54123. 4 interactions.
    STRINGi 1148.slr0551.

    Proteomic databases

    PaxDbi P54123.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA10871 ; BAA10871 ; BAA10871 .
    GeneIDi 952079.
    KEGGi syn:slr0551.
    syy:SYNGTS_2908.
    syz:MYO_129360.
    PATRICi 23843368. VBISynSp132158_3220.

    Phylogenomic databases

    eggNOGi COG0595.
    KOi K12574.
    OMAi KDEKHLI.
    OrthoDBi EOG6P5ZDC.
    PhylomeDBi P54123.

    Family and domain databases

    Gene3Di 3.60.15.10. 1 hit.
    HAMAPi MF_01491. RNase_J_bact.
    InterProi IPR001279. Beta-lactamas-like.
    IPR011108. RMMBL.
    IPR004613. RNase_J.
    IPR001587. RNase_J_CS.
    [Graphical view ]
    PANTHERi PTHR11203:SF22. PTHR11203:SF22. 1 hit.
    Pfami PF00753. Lactamase_B. 1 hit.
    PF07521. RMMBL. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF004803. RnjA. 1 hit.
    SMARTi SM00849. Lactamase_B. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56281. SSF56281. 1 hit.
    TIGRFAMsi TIGR00649. MG423. 1 hit.
    PROSITEi PS01292. UPF0036. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
      Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
      DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27184 / PCC 6803 / N-1.
    2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiRNJ_SYNY3
    AccessioniPrimary (citable) accession number: P54123
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3