Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribonuclease J

Gene

rnj

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).By similarity

Cofactori

Zn2+UniRule annotationNote: Binds up to 2 Zn2+ ions per subunit. It is not clear if Zn2+ or Mg2+ is physiologically important.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi75Zinc 1; catalyticUniRule annotation1
Metal bindingi77Zinc 1; catalyticUniRule annotation1
Metal bindingi79Zinc 2; catalyticUniRule annotation1
Metal bindingi80Zinc 2; catalyticUniRule annotation1
Metal bindingi145Zinc 1; catalyticUniRule annotation1
Metal bindingi167Zinc 1; catalyticUniRule annotation1
Metal bindingi167Zinc 2; catalyticUniRule annotation1
Metal bindingi394Zinc 2; catalyticUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Exonuclease, Hydrolase, Nuclease

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

Metal-binding, RNA-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease JUniRule annotation (EC:3.1.-.-UniRule annotation)
Short name:
RNase JUniRule annotation
Gene namesi
Name:rnjUniRule annotation
Ordered Locus Names:slr0551
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002152731 – 640Ribonuclease JAdd BLAST640

Proteomic databases

PRIDEiP54123.

Interactioni

Subunit structurei

Homodimer, may be a subunit of the RNA degradosome.UniRule annotation

Protein-protein interaction databases

IntActiP54123. 4 interactors.

Structurei

3D structure databases

ProteinModelPortaliP54123.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni368 – 372Substrate bindingUniRule annotation5

Sequence similaritiesi

Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.UniRule annotation

Phylogenomic databases

InParanoidiP54123.
KOiK12574.
OMAiKNTCVFE.
PhylomeDBiP54123.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
HAMAPiMF_01491. RNase_J_bact. 1 hit.
InterProiIPR001279. Metallo-B-lactamas.
IPR011108. RMMBL.
IPR004613. RNase_J.
IPR030854. RNase_J_bac.
IPR001587. RNase_J_CS.
[Graphical view]
PANTHERiPTHR11203:SF22. PTHR11203:SF22. 1 hit.
PfamiPF00753. Lactamase_B. 1 hit.
PF07521. RMMBL. 1 hit.
[Graphical view]
PIRSFiPIRSF004803. RnjA. 1 hit.
SMARTiSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMiSSF56281. SSF56281. 1 hit.
TIGRFAMsiTIGR00649. MG423. 1 hit.
PROSITEiPS01292. UPF0036. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P54123-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKNTQTQAL KILPLGGLHE IGKNTCVFEY DDEILLLDAG LAFPTDDMHG
60 70 80 90 100
VNVVLPDMTY LRENREKIKG MVVTHGHEDH IGGIAYHLKQ FDIPIIYGPR
110 120 130 140 150
LAMALLRDKL EEAGMLERTN LQTVSPREMV RLGKSFVVEF IRNTHSIADS
160 170 180 190 200
YCLAIHTPLG VVMHSGDFKI DHTPIDGEFF DLQKVAEYGE KGVLCLLSDS
210 220 230 240 250
TNAEVPGITP SEASVIPNLD RVFSQAEGRL MVTTFASSVH RVNIILSLAQ
260 270 280 290 300
KHQRKVAVVG RSMLNVIAHA RKLGYIKCPD NLFVPLKAAR NLPDQQQLIL
310 320 330 340 350
TTGSQGEPLA AMTRISNGEH PQIKIRQGDT VVFSANPIPG NTIAVVNTID
360 370 380 390 400
RLMMQGANVI YGKHQGIHVS GHASQEEHKM LLALTRPKFF VPVHGEHRML
410 420 430 440 450
VKHSQMAQAQ GIPSENIVIV NNGDVIELTG DRIRVAGQVP SGIELVDQAG
460 470 480 490 500
IVHESTMAER QQMAEDGLVT VAAALSKTGT LLAYPEVHCR GVVMTIQPKL
510 520 530 540 550
LEELIVRTIE NFLTERWSEF THGSNGSTEV SWNALQKELE SSLQRLIKRE
560 570 580 590 600
LQSSPMVLLM LQTDTPIELD QVPQNVSTVS ATSATPAPRK KVVLTKTPEP
610 620 630 640
KVKAKPEKKV VTTAEPSAQP VSTTKVYRRS RKRSTTSVSS
Length:640
Mass (Da):70,427
Last modified:October 1, 1996 - v1
Checksum:iF4D1CC23EA656E6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10871.1.
PIRiS76024.

Genome annotation databases

EnsemblBacteriaiBAA10871; BAA10871; BAA10871.
KEGGisyn:slr0551.
PATRICi23843368. VBISynSp132158_3220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10871.1.
PIRiS76024.

3D structure databases

ProteinModelPortaliP54123.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP54123. 4 interactors.

Proteomic databases

PRIDEiP54123.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA10871; BAA10871; BAA10871.
KEGGisyn:slr0551.
PATRICi23843368. VBISynSp132158_3220.

Phylogenomic databases

InParanoidiP54123.
KOiK12574.
OMAiKNTCVFE.
PhylomeDBiP54123.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
HAMAPiMF_01491. RNase_J_bact. 1 hit.
InterProiIPR001279. Metallo-B-lactamas.
IPR011108. RMMBL.
IPR004613. RNase_J.
IPR030854. RNase_J_bac.
IPR001587. RNase_J_CS.
[Graphical view]
PANTHERiPTHR11203:SF22. PTHR11203:SF22. 1 hit.
PfamiPF00753. Lactamase_B. 1 hit.
PF07521. RMMBL. 1 hit.
[Graphical view]
PIRSFiPIRSF004803. RnjA. 1 hit.
SMARTiSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMiSSF56281. SSF56281. 1 hit.
TIGRFAMsiTIGR00649. MG423. 1 hit.
PROSITEiPS01292. UPF0036. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRNJ_SYNY3
AccessioniPrimary (citable) accession number: P54123
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.