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P54123

- RNJ_SYNY3

UniProt

P54123 - RNJ_SYNY3

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Protein

Ribonuclease J

Gene

rnj

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).By similarity

Cofactori

Zn2+UniRule annotationNote: Binds up to 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi75 – 751Zinc 1; catalyticUniRule annotation
Metal bindingi77 – 771Zinc 1; catalyticUniRule annotation
Metal bindingi79 – 791Zinc 2; catalyticUniRule annotation
Metal bindingi80 – 801Zinc 2; catalyticUniRule annotation
Metal bindingi145 – 1451Zinc 1; catalyticUniRule annotation
Metal bindingi167 – 1671Zinc 1; catalyticUniRule annotation
Metal bindingi167 – 1671Zinc 2; catalyticUniRule annotation
Metal bindingi394 – 3941Zinc 2; catalyticUniRule annotation

GO - Molecular functioni

  1. endonuclease activity Source: UniProtKB-KW
  2. exonuclease activity Source: UniProtKB-KW
  3. metal ion binding Source: UniProtKB-KW
  4. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Exonuclease, Hydrolase, Nuclease

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

Metal-binding, RNA-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease JUniRule annotation (EC:3.1.-.-UniRule annotation)
Short name:
RNase JUniRule annotation
Gene namesi
Name:rnjUniRule annotation
Ordered Locus Names:slr0551
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 640640Ribonuclease JPRO_0000215273Add
BLAST

Proteomic databases

PaxDbiP54123.

Interactioni

Subunit structurei

Homodimer, may be a subunit of the RNA degradosome.UniRule annotation

Protein-protein interaction databases

IntActiP54123. 4 interactions.
STRINGi1148.slr0551.

Structurei

3D structure databases

ProteinModelPortaliP54123.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni368 – 3725Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0595.
InParanoidiP54123.
KOiK12574.
OMAiKDEKHLI.
OrthoDBiEOG6P5ZDC.
PhylomeDBiP54123.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
HAMAPiMF_01491. RNase_J_bact.
InterProiIPR001279. Beta-lactamas-like.
IPR011108. RMMBL.
IPR004613. RNase_J.
IPR001587. RNase_J_CS.
[Graphical view]
PANTHERiPTHR11203:SF22. PTHR11203:SF22. 1 hit.
PfamiPF00753. Lactamase_B. 1 hit.
PF07521. RMMBL. 1 hit.
[Graphical view]
PIRSFiPIRSF004803. RnjA. 1 hit.
SMARTiSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMiSSF56281. SSF56281. 1 hit.
TIGRFAMsiTIGR00649. MG423. 1 hit.
PROSITEiPS01292. UPF0036. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P54123-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKNTQTQAL KILPLGGLHE IGKNTCVFEY DDEILLLDAG LAFPTDDMHG
60 70 80 90 100
VNVVLPDMTY LRENREKIKG MVVTHGHEDH IGGIAYHLKQ FDIPIIYGPR
110 120 130 140 150
LAMALLRDKL EEAGMLERTN LQTVSPREMV RLGKSFVVEF IRNTHSIADS
160 170 180 190 200
YCLAIHTPLG VVMHSGDFKI DHTPIDGEFF DLQKVAEYGE KGVLCLLSDS
210 220 230 240 250
TNAEVPGITP SEASVIPNLD RVFSQAEGRL MVTTFASSVH RVNIILSLAQ
260 270 280 290 300
KHQRKVAVVG RSMLNVIAHA RKLGYIKCPD NLFVPLKAAR NLPDQQQLIL
310 320 330 340 350
TTGSQGEPLA AMTRISNGEH PQIKIRQGDT VVFSANPIPG NTIAVVNTID
360 370 380 390 400
RLMMQGANVI YGKHQGIHVS GHASQEEHKM LLALTRPKFF VPVHGEHRML
410 420 430 440 450
VKHSQMAQAQ GIPSENIVIV NNGDVIELTG DRIRVAGQVP SGIELVDQAG
460 470 480 490 500
IVHESTMAER QQMAEDGLVT VAAALSKTGT LLAYPEVHCR GVVMTIQPKL
510 520 530 540 550
LEELIVRTIE NFLTERWSEF THGSNGSTEV SWNALQKELE SSLQRLIKRE
560 570 580 590 600
LQSSPMVLLM LQTDTPIELD QVPQNVSTVS ATSATPAPRK KVVLTKTPEP
610 620 630 640
KVKAKPEKKV VTTAEPSAQP VSTTKVYRRS RKRSTTSVSS
Length:640
Mass (Da):70,427
Last modified:October 1, 1996 - v1
Checksum:iF4D1CC23EA656E6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10871.1.
PIRiS76024.
RefSeqiNP_442800.1. NC_000911.1.
YP_005652861.1. NC_017277.1.
YP_007452676.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA10871; BAA10871; BAA10871.
GeneIDi952079.
KEGGisyn:slr0551.
PATRICi23843368. VBISynSp132158_3220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10871.1 .
PIRi S76024.
RefSeqi NP_442800.1. NC_000911.1.
YP_005652861.1. NC_017277.1.
YP_007452676.1. NC_020286.1.

3D structure databases

ProteinModelPortali P54123.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P54123. 4 interactions.
STRINGi 1148.slr0551.

Proteomic databases

PaxDbi P54123.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA10871 ; BAA10871 ; BAA10871 .
GeneIDi 952079.
KEGGi syn:slr0551.
PATRICi 23843368. VBISynSp132158_3220.

Phylogenomic databases

eggNOGi COG0595.
InParanoidi P54123.
KOi K12574.
OMAi KDEKHLI.
OrthoDBi EOG6P5ZDC.
PhylomeDBi P54123.

Family and domain databases

Gene3Di 3.60.15.10. 1 hit.
HAMAPi MF_01491. RNase_J_bact.
InterProi IPR001279. Beta-lactamas-like.
IPR011108. RMMBL.
IPR004613. RNase_J.
IPR001587. RNase_J_CS.
[Graphical view ]
PANTHERi PTHR11203:SF22. PTHR11203:SF22. 1 hit.
Pfami PF00753. Lactamase_B. 1 hit.
PF07521. RMMBL. 1 hit.
[Graphical view ]
PIRSFi PIRSF004803. RnjA. 1 hit.
SMARTi SM00849. Lactamase_B. 1 hit.
[Graphical view ]
SUPFAMi SSF56281. SSF56281. 1 hit.
TIGRFAMsi TIGR00649. MG423. 1 hit.
PROSITEi PS01292. UPF0036. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
    Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
    DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27184 / PCC 6803 / N-1.
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiRNJ_SYNY3
AccessioniPrimary (citable) accession number: P54123
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 26, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3