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P54093

- VP2_CAV82

UniProt

P54093 - VP2_CAV82

Protein

Dual specificity protein phosphatase VP2

Gene

VP2

Organism
Chicken anemia virus (isolate Japan 82-2) (CAV)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    May act as a scaffold protein in virion assembly. May also play a role in intracellular signaling during viral replication By similarity.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei95 – 951Phosphocysteine intermediateBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Dual specificity protein phosphatase VP2 (EC:3.1.3.16, EC:3.1.3.48)
    Gene namesi
    Name:VP2
    OrganismiChicken anemia virus (isolate Japan 82-2) (CAV)
    Taxonomic identifieri73476 [NCBI]
    Taxonomic lineageiVirusesssDNA virusesCircoviridaeGyrovirus
    Virus hostiGallus gallus (Chicken) [TaxID: 9031]
    ProteomesiUP000008443: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 216216Dual specificity protein phosphatase VP2PRO_0000223003Add
    BLAST

    Expressioni

    Inductioni

    VP1 and VP2 are detected 12 hours post infection, while VP3 only after 24 hours.

    Keywords - Developmental stagei

    Early protein

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the gyrovirus protein VP2 family.Curated

    Family and domain databases

    InterProiIPR004118. HEV_TT_virus_Orf2/Gyrovir_Vp2.
    [Graphical view]
    PfamiPF02957. TT_ORF2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P54093-1 [UniParc]FASTAAdd to Basket

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    MHGNGGQPAA GGSESALSRE GQPGPSGAAQ GQVISNERSP RRYSTRTING    50
    VQATNKFTAV GNPSLQRDPD WYRWNYNHSI AVWLRECSRS HAKICNCGQF 100
    RKHWFQECAG LEDRSTQASL EEAILRPLRV QGKRAKRKLD YHYSQPTPNR 150
    KKVYKTVRWK DELADREADF TPSEEDGGTT SSDFDEDINF DIGGDSGIVD 200
    ELLGRPFTTP APVRIV 216
    Length:216
    Mass (Da):24,139
    Last modified:October 1, 1996 - v1
    Checksum:iE23169F592BDDE52
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D31965 Genomic DNA. Translation: BAA06732.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D31965 Genomic DNA. Translation: BAA06732.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR004118. HEV_TT_virus_Orf2/Gyrovir_Vp2.
    [Graphical view ]
    Pfami PF02957. TT_ORF2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiVP2_CAV82
    AccessioniPrimary (citable) accession number: P54093
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3